Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2016-08-03Clinical Trial Update: Tailored Implementation Intervention for Managing Depressed Elderly Patients in Primary Care [NA]
Completed clinical trial evaluating a tailored implementation intervention to manage depression in elderly patients in primary care.
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CLINICAL_TRIALS trial_result · 2016-08-02Clinical Trial Update: Depression Care for Hospitalized Coronary Heart Disease Patients: Prospective Cohort Study
This update reports results from a prospective cohort study on depression care for hospitalized patients with coronary heart disease, and no…
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FDA approval · 2016-08-01FDA Approved: PROZAC — Supplemental Application (Dista Products Company)
FDA approves a supplemental application for PROZAC (fluoxetine hydrochloride) submitted by Dista Products Company.
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FDA approval · 2016-07-29FDA Approved: DESVENLAFAXINE — Original Application (Actavis Pharma, Inc.)
FDA approved Actavis Pharma's original application for generic desvenlafaxine for the treatment of major depressive disorder.
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CLINICAL_TRIALS research · 2016-07-28Clinical Trial Update: Prevalence of and Factors Associated With Metabolic Syndrome in Schizophrenia
This completed study investigates how prevalent metabolic syndrome is among individuals with schizophrenia and examines factors associated w…
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CLINICAL_TRIALS trial_result · 2016-07-28Clinical Trial Update: Reliability and Validity of Thai Calgary Depression Scale of Schizophrenia (CDSS)
A completed clinical trial evaluating the reliability and validity of the Thai version of the Calgary Depression Scale for Schizophrenia (CD…
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CLINICAL_TRIALS trial_result · 2016-07-28Clinical Trial Update: Identifying Factors That Predict Antidepressant Treatment Response [NA]
Completed Emory University clinical trial investigating factors that predict response to antidepressant treatment in depression; results wer…
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CLINICAL_TRIALS research · 2016-07-28Clinical Trial Update: Predictive Nature of Total Cholesterol Threshold: Possible Link to Suicidal Behavior [NA]
This clinical trial update examines whether a total cholesterol threshold may predict suicidal behavior in individuals with major depressive…
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CLINICAL_TRIALS trial_result · 2016-07-28Clinical Trial Update: A Clinical Trial for the Treatment of Depression With Repetitive Transcranial Magnetic Stimulation (rTMS) [NA]
The clinical trial evaluating repetitive transcranial magnetic stimulation (rTMS) for major depressive disorder has completed.
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CLINICAL_TRIALS research · 2016-07-28Clinical Trial Update: Inflammatory Markers and Resistant Depression [NA]
This clinical trial update examines inflammatory markers in major depressive disorder and treatment-resistant depression, with the trial sta…
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CLINICAL_TRIALS trial_result · 2016-07-20Clinical Trial Update: Ability to Cope With Type 1 Diabetes
Completed clinical trial update examining coping with Type 1 diabetes, with depression as the studied condition.
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CLINICAL_TRIALS trial_result · 2016-07-18Clinical Trial Update: The Effects of Playing High School Football on Later Life Cognitive Functioning and Mental Health
An update on a completed clinical trial examining whether playing high school football affects cognitive function and mental health later in…
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FDA approval · 2016-07-15FDA Approved: BUPROPION HYDROCHLORIDE — Supplemental Application (Epic Pharma LLC)
FDA approved a Supplemental Application for bupropion hydrochloride (Epic Pharma LLC), signaling regulatory approval for this generic produc…
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FDA approval · 2016-07-15FDA Approved: DESVENLAFAXINE SUCCINATE — Supplemental Application (Lupin Pharmaceuticals, Inc.)
FDA approved Lupin Pharmaceuticals' supplemental application for desvenlafaxine succinate (generic) under an ANDA.
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CLINICAL_TRIALS trial_result · 2016-07-15Clinical Trial Update: Problem-Solving Therapy for People With Major Depression and Chronic Obstructive Pulmonary Disease [NA]
This clinical trial update notes the completion of a study evaluating problem-solving therapy for adults with major depressive disorder and …
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CLINICAL_TRIALS other · 2016-07-14Clinical Trial Update: Ability to Cope With Type 1 Diabetes
This entry reports a completed clinical trial (NCT00206349) focusing on coping with Type 1 diabetes in people with depression. The snippet o…
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CLINICAL_TRIALS trial_result · 2016-07-13Clinical Trial Update: SAM-e for the Treatment of Depression in Patients With Parkinson's Disease [Phase 2, Phase 3]
Clinical trial update reporting completed Phase 2 and Phase 3 results for SAM-e in treating depression in patients with Parkinson's disease;…
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CLINICAL_TRIALS research · 2016-07-13Clinical Trial Update: Evaluation of Emotional Status and Coronary Flow Characteristics by TIMI Frame Count Method [NA]
Clinical trial update evaluating how emotional status (anxiety and depression) relates to coronary flow characteristics measured by the TIMI…
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CLINICAL_TRIALS trial_result · 2016-07-13Clinical Trial Update: A Double Blind, Randomized Placebo Controlled Study of the Efficacy, Safety and of Quetiapine Fumarate (Seroquel®) as Potentiation SSRI's, and SNRI's Treatment in Major Depression With Anxiety [Phase 4]
This Phase 4 double-blind, randomized, placebo-controlled study evaluated quetiapine fumarate (Seroquel) as augmentation to SSRI/SNRI therap…
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CLINICAL_TRIALS research · 2016-07-12Clinical Trial Update: Behavioral and Immunological Factors in Coronary Disease
The NHLBI-sponsored trial investigated behavioral and immunological factors in coronary disease, and the study status is completed.
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CLINICAL_TRIALS trial_result · 2016-07-11Clinical Trial Update: A Study to Evaluate the Impact of Escitalopram on Quality of Life and Social Functionality in Patients With Major Depressive Disorder With Anxiety Symptom [Phase 4]
Phase 4 trial assessing escitalopram's impact on quality of life and social functioning in adults with major depressive disorder with anxiet…
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CLINICAL_TRIALS trial_result · 2016-07-11Clinical Trial Update: Effectiveness of a Training Intervention on Mental Health of Parents for Intellectually Disabled Children in Malawi [NA]
A completed clinical trial assessed the effectiveness of a training intervention on the mental health of parents of children with intellectu…
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CLINICAL_TRIALS trial_result · 2016-07-11Clinical Trial Update: Sudarshan Kriya Yoga and Cardiac Autonomic Control in Patients With Anxiety-Depression Disorders [NA]
This clinical trial update reports the completion of a study evaluating Sudarshan Kriya Yoga and its effect on cardiac autonomic control in …
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CLINICAL_TRIALS withdrawal · 2016-07-07Clinical Trial Update: Brexpiprazole (OPC 34712) Trial in the Treatment of Adults With Major Depressive Disorder and Irritability [Phase 3]
A Phase 3 clinical trial of brexpiprazole for adults with major depressive disorder and irritability has been withdrawn.
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CLINICAL_TRIALS research · 2016-07-06Clinical Trial Update: Neuroinflammation, Serotonin, Impulsivity and Suicide [NA]
This clinical trial update concerns research on neuroinflammation, serotonin, impulsivity, and suicide in individuals with major depressive …