Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS withdrawal · 2016-10-13Clinical Trial Update: A Prospective Study of Body Image, Social Avoidance and Distress and Psychological Functioning in Burn Patients
The trial evaluating body image, social avoidance, distress, and psychological functioning in burn patients has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2016-10-07Clinical Trial Update: Primary Care iSBIRT to Reduce Serious Teen Health Risks [Phase 1, Phase 2]
Phase 1/2 trial of iSBIRT to reduce teen risk behaviors has been withdrawn.
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FDA approval · 2016-10-07FDA Approved: ARIPIPRAZOLE — Original Application (Macleods Pharmaceuticals Limited)
The FDA approved Macleods Pharmaceuticals Limited's generic aripiprazole (ANDA 204111) based on its original application.
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CLINICAL_TRIALS research · 2016-10-05Clinical Trial Update: The Investigation of the Depression in Osteoarthritis
Clinical trial update from Dalian Municipal Central Hospital studying depression in individuals with osteoarthritis. The current status of t…
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CLINICAL_TRIALS research · 2016-10-05Clinical Trial Update: Music Therapy for Major Depressive Disorder Residual Symptoms [NA]
A clinical trial update on music therapy for residual symptoms in Major Depressive Disorder; the current study status is not provided.
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CLINICAL_TRIALS trial_result · 2016-10-04Clinical Trial Update: Efficacy of an Online Program for the Treatment of Mild and Moderate Depression [NA]
A clinical trial update evaluating the efficacy of an online program for treating mild to moderate depression; no results or status details …
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CLINICAL_TRIALS trial_result · 2016-10-03Clinical Trial Update: Study of Brain Response to Emotional Pictures Using a fMRI While on Duloxetine [Phase 4]
Phase 4 study investigating how duloxetine affects brain responses to emotional pictures in people with major depressive disorder; the trial…
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CLINICAL_TRIALS trial_result · 2016-10-03Clinical Trial Update: Strategic Use of New Generation Antidepressants for Depression [Phase 4]
A Phase 4 clinical trial evaluating the strategic use of new-generation antidepressants for major depressive disorder has completed.
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CLINICAL_TRIALS trial_result · 2016-09-30Clinical Trial Update: Brain Imaging of Quetiapine Response in Anxious Depression [Phase 4]
Phase 4 brain imaging study evaluating quetiapine response in anxious depression has completed, with results posted in 2016.
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CLINICAL_TRIALS trial_result · 2016-09-30Clinical Trial Update: Telemedicine for Women With Anhedonia in Bipolar and Unipolar Disorder [NA]
ClinicalTrials.gov update indicates the completion of a telemedicine study examining anhedonia in women with bipolar and unipolar depression…
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CLINICAL_TRIALS withdrawal · 2016-09-30Clinical Trial Update: Vortioxetine for MDD, Cognition, and Systemic Inflammatory Biomarkers [Phase 4]
Phase 4 trial of vortioxetine for major depressive disorder, cognition, and systemic inflammatory biomarkers in breast cancer patients was w…
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CLINICAL_TRIALS trial_result · 2016-09-29Clinical Trial Update: Electrical Stimulation in Patients With Unipolar Major Depression [Phase 2]
A Phase 2 trial evaluating electrical stimulation for unipolar major depression has completed.
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CLINICAL_TRIALS trial_result · 2016-09-29Clinical Trial Update: Effectiveness of Nimodipine Plus Antidepressant Medication in Treating Vascular Depression [Phase 4]
This Phase 4 clinical trial update evaluated nimodipine added to an antidepressant for vascular depression. The study was terminated and res…
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CLINICAL_TRIALS trial_result · 2016-09-29Clinical Trial Update: Electrical Stimulation in Patients With Unipolar Major Depression [Phase 2]
A Phase 2 clinical trial evaluating electrical stimulation for unipolar major depression has completed.
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FDA approval · 2016-09-29FDA Approved: ARIPIPRAZOLE — Original Application (Dr.Reddys Laboratories Inc)
FDA approves Dr. Reddy's Laboratories' generic aripiprazole under an original ANDA application. This action provides a generic option for th…
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CLINICAL_TRIALS trial_result · 2016-09-27Clinical Trial Update: A Trial on Metacognitive Training for Depression (D-MCT) [NA]
The clinical trial evaluating metacognitive training for depression (D-MCT) has completed.
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CLINICAL_TRIALS research · 2016-09-27Clinical Trial Update: Electrodermal Hyporeactivity And Depression [NA]
An update on a study examining electrodermal hyporeactivity in individuals diagnosed with depression; the trial status is unknown.
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CLINICAL_TRIALS research · 2016-09-27Clinical Trial Update: Influence of Depressive Mood on Rehab Outcome [NA]
This entry notes an ongoing clinical trial funded by Johannes Kepler University of Linz evaluating how depressive mood affects rehabilitatio…
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FDA approval · 2016-09-23FDA Approved: REXULTI — Supplemental Application (Otsuka America Pharmaceutical, Inc.)
The FDA approved a supplemental application for Rexulti (brexpiprazole) from Otsuka America Pharmaceutical, Inc., under NDA 205422.
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CLINICAL_TRIALS research · 2016-09-22Clinical Trial Update: Prognosis of Depression in the Elderly (PRODE). A Multicentre, Longitudinal Study of Elderly Depressed Patients.
A completed multicentre longitudinal study investigating the prognosis of depression in elderly patients, including cases with dementia, wit…
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CLINICAL_TRIALS research · 2016-09-22Clinical Trial Update: Evaluating CBT Delivered by Community Health Workers on Maternal Mental Health and Infant Cognitive Development in Insecure Environments [NA]
This clinical trial evaluates cognitive behavioral therapy delivered by community health workers to address maternal anxiety and depression …
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CLINICAL_TRIALS research · 2016-09-21Clinical Trial Update: A Longitudinal Observational Cohort Study of NSI-189, With Out-Patients With Major Depressive Disorder
A longitudinal observational cohort study is being conducted to evaluate NSI-189 in outpatients with major depressive disorder. The current …
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CLINICAL_TRIALS research · 2016-09-21Clinical Trial Update: Clinical Trial of the Use of Ketamine in Treatment Resistant Depression [Phase 4]
This entry notes a Phase 4 clinical trial evaluating ketamine for treatment-resistant depression, with the trial status currently unknown.
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CLINICAL_TRIALS trial_result · 2016-09-16Clinical Trial Update: Enhancing Delivery of Problem Solving Therapy Using SmartPhone Technology [Phase 1, Phase 2]
Phase 1/Phase 2 trial evaluating the delivery of Problem Solving Therapy via smartphone technology for depression and anxiety completed with…
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CLINICAL_TRIALS research · 2016-09-16Clinical Trial Update: Predictors of Suicidal Behavior in Depression [NA]
A clinical trial update describing a study that investigates predictors of suicidal behavior in people with depression; status is not specif…