Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2016-11-23Clinical Trial Update: Acoustical Properties of Speech as Indicators of Suicidal Risk
A completed clinical study evaluating whether acoustical properties of speech can indicate suicidal risk in people with depression.
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CLINICAL_TRIALS trial_result · 2016-11-23Clinical Trial Update: Prevention of Mood Disorders by Folic Acid Supplementation [NA]
A completed University of Oxford clinical trial evaluating whether folic acid supplementation can prevent mood disorders, including major de…
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CLINICAL_TRIALS withdrawal · 2016-11-21Clinical Trial Update: Neuroimaging Predictors of Antidepressant Treatment Outcome [Phase 2]
A Phase 2 clinical trial from the University of Michigan investigating whether neuroimaging can predict antidepressant treatment outcomes fo…
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CLINICAL_TRIALS trial_result · 2016-11-18Clinical Trial Update: IV Ibuprofen for Post-Electroconvulsive Therapy Myalgia [Phase 4]
A Phase 4 trial evaluating intravenous ibuprofen for post-electroconvulsive therapy myalgia was terminated, and results were posted in 2016.
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CLINICAL_TRIALS trial_result · 2016-11-18Clinical Trial Update: Study of Genetic Differences in People With Depression
A UCLA-sponsored study investigating genetic differences in people with major depressive disorder has completed.
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CLINICAL_TRIALS trial_result · 2016-11-17Clinical Trial Update: Effectiveness of Story-Centred Care Intervention Program in Older Persons Living in Long-term Care Facilities [NA]
This update reports the completion of a clinical trial assessing the effectiveness of a story-centered care intervention for depression in o…
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CLINICAL_TRIALS research · 2016-11-15Clinical Trial Update: The Effect of Group Treatment for Depression: A Study of Metacognitive Therapy, Mindfulness and Support Groups [NA]
This document notes an ongoing study evaluating group treatments for depression, including metacognitive therapy, mindfulness, and support g…
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CLINICAL_TRIALS research · 2016-11-15Clinical Trial Update: Effect of a Self-care Intervention on Depression in People With Age-related Macular Degeneration or Diabetic Retinopathy [NA]
A completed clinical trial evaluated whether a self-care intervention can reduce depressive symptoms in people with age-related macular dege…
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CLINICAL_TRIALS trial_result · 2016-11-11Clinical Trial Update: Is Narrative Reformulation During Cognitive Analytic Therapy Helpful? [Phase 2, Phase 3]
This update summarizes completed Phase 2 and Phase 3 trials evaluating whether narrative reformulation during cognitive analytic therapy imp…
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CLINICAL_TRIALS trial_result · 2016-11-10Clinical Trial Update: Computer-Assisted Cognitive-Behavioral Therapy for Adolescent Depression [NA]
This document reports the completion of a clinical trial evaluating computer-assisted cognitive-behavioral therapy for adolescent depression…
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CLINICAL_TRIALS research · 2016-11-10Clinical Trial Update: tDCS for Treatment of Depression in Parkinson's Disease [NA]
Clinical trial evaluating transcranial direct current stimulation (tDCS) for depression in Parkinson's disease; the current status of the tr…
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CLINICAL_TRIALS trial_result · 2016-11-08Clinical Trial Update: Dose-finding Study With Lu AA24530 in Major Depressive Disorder [Phase 2]
Phase 2 dose-finding trial of Lu AA24530 (vortioxetine) for major depressive disorder has been completed.
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CLINICAL_TRIALS trial_result · 2016-11-08Clinical Trial Update: Efficacy and Tolerability of Escitalopram and Duloxetine in Outpatients With Major Depressive Disorder [Phase 4]
Phase 4 clinical trial update evaluating the efficacy and tolerability of escitalopram and duloxetine in outpatients with major depressive d…
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CLINICAL_TRIALS trial_result · 2016-11-08Clinical Trial Update: Contingency Management of Psychostimulant Abuse in the Severely Mentally Ill [NA]
A completed clinical trial evaluating contingency management for stimulant use disorder in individuals with severe mental illness.
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CLINICAL_TRIALS withdrawal · 2016-11-08Clinical Trial Update: Mood and Behavior Changes Among Overweight Adolescent Females
A University of Kentucky trial evaluating mood and behavior changes in overweight adolescent females has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2016-11-08Clinical Trial Update: The Effects of Vilazodone on Glutamate in the Anterior Cingulate Cortex in Anxious Unipolar Depressives [Phase 4]
A Phase 4 trial evaluating vilazodone's effect on glutamate in the anterior cingulate cortex for patients with anxious major depressive diso…
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CLINICAL_TRIALS trial_result · 2016-11-07Clinical Trial Update: Light Therapy for Bipolar Disorder. Efficacy of Light Therapy for Bipolar Depression: A Randomized Controlled Trial [Phase 3]
Phase 3 randomized controlled trial evaluating the efficacy of light therapy for bipolar depression. Results were posted in 2016.
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CLINICAL_TRIALS trial_result · 2016-11-07Clinical Trial Update: Safety and Efficacy of MK-6096 as Adjunctive Therapy in Participants With Major Depressive Disorder And Partial Response to Antidepressant Monotherapy (MK-6096-022) [Phase 2]
Phase 2 clinical trial update for MK-6096 as adjunctive therapy in participants with major depressive disorder and partial response to antid…
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CLINICAL_TRIALS trial_result · 2016-11-07Clinical Trial Update: Study of Medication and Placebo Response in Major Depression [Phase 4]
A Phase 4 study comparing a medication to placebo in major depressive disorder has completed.
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CLINICAL_TRIALS trial_result · 2016-11-02Clinical Trial Update: A Study of RO4917523 in Patients With Treatment Resistant Depression [Phase 2]
Phase 2 study of RO4917523 for treatment-resistant depression has completed.
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CLINICAL_TRIALS trial_result · 2016-11-02Clinical Trial Update: ARTDeCo Study: A Study of RO4995819 in Patients With Major Depressive Disorder And Inadequate Response to Ongoing Antidepressant Treatment [Phase 2]
The ARTDeCo Phase 2 study of RO4995819 in adults with major depressive disorder who have inadequate response to ongoing antidepressant treat…
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CLINICAL_TRIALS trial_result · 2016-11-02Clinical Trial Update: A Study of the Safety, Tolerability, and Pharmacokinetics of Multiple-Ascending Dose Basimglurant in Healthy Subjects and in Patients With Major Depressive Disorder (MDD) [Phase 1]
Phase 1 study evaluating the safety, tolerability, and pharmacokinetics of escalating doses of basimglurant in healthy volunteers and patien…
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CLINICAL_TRIALS trial_result · 2016-11-02Clinical Trial Update: MARIGOLD Study: A Study of RO4917523 Versus Placebo as Adjunctive Therapy in Patients With Major Depressive Disorder and an Inadequate Response to Ongoing Antidepressant Therapy [Phase 2]
MARIGOLD is a Phase 2 trial comparing RO4917523 to placebo as adjunctive therapy for major depressive disorder with inadequate response to o…
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FDA approval · 2016-11-01FDA Approved: QUETIAPINE FUMARATE — Original Application (Accord Healthcare Inc.)
The FDA approved Accord Healthcare Inc.'s original application for quetiapine fumarate, granting marketing authorization for a generic versi…
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CLINICAL_TRIALS trial_result · 2016-11-01Clinical Trial Update: Treating Depression With Physical Exercise [NA]
A completed clinical trial from Umeå University investigated physical exercise as a treatment for Depression.