Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-04-18Clinical Trial Update: Treatment of Patients With Major Depressive Disorder With MK0869 (0869-061) [Phase 3]
A Phase 3 clinical trial of MK0869 for Major Depressive Disorder has completed.
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FDA approval · 2017-04-17FDA Approved: BUPROPION HYDROCHLORIDE SR — Supplemental Application (Dr. Reddys Laboratories Inc.)
The FDA approved a supplemental application for Bupropion hydrochloride SR from Dr. Reddy's Laboratories Inc., enabling marketing of this ge…
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CLINICAL_TRIALS trial_result · 2017-04-14Clinical Trial Update: N-methyl-D-aspartate Antagonist (Ketamine) Augmentation of Electroconvulsive Treatment for Severe Major Depression [Phase 4]
A Phase 4 trial evaluated whether ketamine augmentation of electroconvulsive therapy improves outcomes in severe major depressive disorder. …
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CLINICAL_TRIALS trial_result · 2017-04-14Clinical Trial Update: Neurobiological Bases of Placebo Response in Major Depressive Disorder [Phase 4]
Phase 4 clinical trial studying the neurobiological bases of placebo response in major depressive disorder; the study was terminated with re…
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CLINICAL_TRIALS trial_result · 2017-04-13Clinical Trial Update: rTMS for Motor and Mood Symptoms of Parkinson's Disease [NA]
This clinical trial evaluated repetitive transcranial magnetic stimulation (rTMS) for motor and mood symptoms in Parkinson's disease; result…
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CLINICAL_TRIALS trial_result · 2017-04-13Clinical Trial Update: Preventing Post-Operative Delirium in Patients Undergoing a Pneumonectomy, Esophagectomy or Thoracotomy [Phase 4]
Indiana University completed a Phase 4 trial evaluating interventions to prevent post-operative delirium in patients undergoing pneumonectom…
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CLINICAL_TRIALS trial_result · 2017-04-13Clinical Trial Update: Treatment of Depression in Nursing Homes [NA]
A completed clinical trial evaluating treatment for depression in nursing homes.
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CLINICAL_TRIALS trial_result · 2017-04-13Clinical Trial Update: Self-guided Depression Treatment on Long-duration Spaceflights: A Continuation Study [NA]
This document reports a completed continuation study evaluating self-guided depression treatment for long-duration spaceflight missions.
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CLINICAL_TRIALS trial_result · 2017-04-13Clinical Trial Update: The Implantable Cardioverter-defibrillators (ICD)/Device Expectations, Adaptations, and Successes Study
The ICD/device expectations, adaptations, and successes study has completed, reporting outcomes related to depression, anxiety, and post-tra…
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CLINICAL_TRIALS trial_result · 2017-04-13Clinical Trial Update: Evaluating a Behavioral Activities Treatment Program for Depressed Nursing Home Residents [NA]
This clinical trial update reports completion of a study evaluating a behavioral activities treatment program for depressed nursing home res…
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CLINICAL_TRIALS trial_result · 2017-04-12Clinical Trial Update: Depakote ER in Bipolar Depression [Phase 4]
Phase 4 trial results for Depakote ER in bipolar depression have been completed and results posted.
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FDA approval · 2017-04-12FDA Approved: BUPROPION HYDROCHLORIDE (XL) — Original Application (ScieGen Pharmaceuticals,Inc.)
FDA approved ScieGen Pharmaceuticals' generic bupropion hydrochloride extended-release (XL) for the same indications as the reference produc…
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CLINICAL_TRIALS trial_result · 2017-04-11Clinical Trial Update: A Study to Assess the Effect and Safety of AZD6765 in Patients With Major Depressive Disorder [Phase 2]
A phase 2 study evaluating the efficacy and safety of AZD6765 (lanicemine) in adults with Major Depressive Disorder has completed, with resu…
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FDA label_change · 2017-04-11FDA Approved: TRINTELLIX — Supplemental Application (Takeda Pharmaceuticals America, Inc.)
The FDA approved a supplemental application for Trintellix (vortioxetine) from Takeda Pharmaceuticals America, updating the product labeling…
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CLINICAL_TRIALS trial_result · 2017-04-11Clinical Trial Update: Iloperidone Augmentation of SSRIs for Patients With Major Depressive Disorder With Residual Anger and Irritability [Phase 4]
Phase 4 trial evaluating augmentation of SSRIs with iloperidone in adults with major depressive disorder and residual anger/irritability. Re…
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CLINICAL_TRIALS trial_result · 2017-04-11Clinical Trial Update: Depression in Alzheimer's Disease-2 [Phase 2, Phase 3]
The Depression in Alzheimer's Disease-2 trial, covering Phase 2 and Phase 3, has completed with results posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-04-11Clinical Trial Update: Dynamic Measures of Neurochemistry in Mood Disorders [Phase 4]
A completed Phase 4 clinical trial from Vanderbilt University Medical Center studying dynamic neurochemical measures in mood disorders (depr…
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CLINICAL_TRIALS trial_result · 2017-04-11Clinical Trial Update: Prolonging Remission in Depressed Elderly (PRIDE) [Phase 4]
This Phase 4 study completed evaluating strategies to prolong remission in elderly patients with depression.
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CLINICAL_TRIALS trial_result · 2017-04-11Clinical Trial Update: Aerobic Exercise as add-on Treatment for Inpatients With Depression [NA]
The clinical trial examining aerobic exercise as an add-on treatment for inpatients with depression has completed.
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CLINICAL_TRIALS trial_result · 2017-04-10Clinical Trial Update: Decreasing Risk of Coronary Artery Disease in Schizophrenia by Omega-3 Fatty Acid Supplementation [Phase 2]
Phase 2 trial evaluating whether omega-3 fatty acid supplementation lowers coronary artery disease risk in people with schizophrenia or schi…
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CLINICAL_TRIALS trial_result · 2017-04-10Clinical Trial Update: Cognitive Behavioral vs. Interpersonal Therapy (IPT) Prevention of Depression in Adolescents [NA]
This completed clinical trial compared Cognitive Behavioral Therapy (CBT) to Interpersonal Therapy (IPT) for preventing depression in adoles…
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CLINICAL_TRIALS trial_result · 2017-04-10Clinical Trial Update: The Fibrosis-Lymphedema Continuum in Head and Neck Cancer
A completed clinical trial update examining the relationship between fibrosis and lymphedema in head and neck cancer. The report highlights …
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CLINICAL_TRIALS trial_result · 2017-04-10Clinical Trial Update: Detecting Depression and Bipolar Disorder in Adolescents Using a Biomarker Panel
The clinical trial evaluating a serum biomarker panel to detect major depressive disorder and bipolar disorder in adolescents was terminated…
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CLINICAL_TRIALS trial_result · 2017-04-07Clinical Trial Update: Sleep to Activate Mood Promotion [NA]
The University of Michigan conducted a completed clinical trial evaluating sleep-based strategies to improve mood in people with depression;…
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FDA approval · 2017-04-06FDA Approved: DULOXETINE — Supplemental Application (Zydus Lifesciences Limited)
The FDA approved a supplemental application for duloxetine submitted by Zydus Lifesciences Limited, advancing the regulatory status of the g…