Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-05-23Clinical Trial Update: Lisdexamfetamine Dimesylate in Residual Symptoms and Cognitive Impairment in Major Depressive Disorder. [Phase 4]
Phase 4 trial update investigates lisdexamfetamine dimesylate for residual symptoms and cognitive impairment in major depressive disorder; r…
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CLINICAL_TRIALS research · 2017-05-23Clinical Trial Update: Epidural Stimulation for Resistant Depression Treatment [Phase 2]
This entry reports a Phase 2 clinical trial evaluating epidural electrical stimulation for treatment-resistant major depressive disorder. Th…
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CLINICAL_TRIALS trial_result · 2017-05-22Clinical Trial Update: Trial of Citalopram for the Prevention of Depression [Phase 3]
Phase 3 trial assessing whether citalopram can prevent depression in individuals with HIV infection or Hepatitis C; the study has completed.
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CLINICAL_TRIALS trial_result · 2017-05-19Clinical Trial Update: A Pilot Trial of Interpersonal Psychotherapy for the Treatment of Depression in Patients With Prostate, Colorectal, Lung and Pancreatic Cancer [NA]
A pilot trial evaluating interpersonal psychotherapy for depression in patients with prostate, colorectal, lung, and pancreatic cancer was t…
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CLINICAL_TRIALS trial_result · 2017-05-19Clinical Trial Update: Use of Multiple Brain Imaging Modalities (PET and MRS) to Identify Metabolic Abnormalities in Major Depression
This clinical trial update reports on a study using PET and magnetic resonance spectroscopy to identify metabolic abnormalities in major dep…
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CLINICAL_TRIALS trial_result · 2017-05-18Clinical Trial Update: Internet Delivered Intervention Program for the Prevention and Treatment of Depression [NA]
A completed clinical trial evaluating an internet-delivered intervention program for the prevention and treatment of depression.
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FDA approval · 2017-05-18FDA Approved: DULOXETINE — Original Application (Solco Healthcare US, LLC)
FDA approved Solco Healthcare US, LLC's original application for duloxetine, enabling the marketing of a generic duloxetine product.
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CLINICAL_TRIALS trial_result · 2017-05-17Clinical Trial Update: Study of Lurasidone in Treating Antipsychotic Naive or Quasi-Naive Children and Adolescents [Phase 2]
Phase 2 study evaluating lurasidone in antipsychotic-naive or quasi-naive children and adolescents with schizophrenia-spectrum and mood diso…
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FDA approval · 2017-05-17FDA Approved: ESCITALOPRAM OXALATE — Original Application (Amneal Pharmaceuticals LLC)
FDA approved Amneal Pharmaceuticals' original application for escitalopram oxalate, a generic version of escitalopram used to treat major de…
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CLINICAL_TRIALS safety_alert · 2017-05-17Clinical Trial Update: Intravenous Iron May Increase Depression Among Hemodialysis Patients
A completed clinical trial suggests intravenous iron in hemodialysis patients may be associated with an increased risk of depression. The fi…
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FDA approval · 2017-05-17FDA Approved: QUETIAPINE — Original Application (Lupin Pharmaceuticals, Inc.)
FDA approves Lupin Pharmaceuticals' generic quetiapine (quetiapine) for the treatment of schizophrenia and bipolar disorder, expanding acces…
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CLINICAL_TRIALS trial_result · 2017-05-16Clinical Trial Update: Imaging the Nucleus Accumbens in Major Depressed Patients 'Treated With Pramipexole [Phase 4]
A Phase 4 trial investigating pramipexole for major depressive disorder focused on nucleus accumbens imaging and was terminated; results wer…
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CLINICAL_TRIALS trial_result · 2017-05-15Clinical Trial Update: Efficacy, Safety, and Tolerability Study of AVP-786 as an Adjunctive Therapy in Patients With Major Depressive Disorder With an Inadequate Response to Antidepressant Treatment [Phase 2]
This document reports the completion of a Phase 2 trial evaluating AVP-786 as an adjunctive treatment for major depressive disorder in patie…
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CLINICAL_TRIALS trial_result · 2017-05-12Clinical Trial Update: Aging Brain Changes, Executive Dysfunction and Depression [Phase 4]
Phase 4 trial results have been completed and posted, led by Weill Medical College of Cornell University, examining aging-related brain chan…
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CLINICAL_TRIALS trial_result · 2017-05-12Clinical Trial Update: ADAPT: Addressing Depression and Pain Together [Phase 4]
A Phase 4 trial evaluating a combined approach to treating depression and back pain completed, with results posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-05-12Clinical Trial Update: Open Treatment of Minocycline in Geriatric Depression [NA]
This clinical trial update reports on open treatment with minocycline in geriatric depression and notes that results were posted in May 2017…
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CLINICAL_TRIALS research · 2017-05-12Clinical Trial Update: Patient Decision Aid for Antidepressant Use in Pregnancy [NA]
This record notes the completion of a clinical trial evaluating a patient decision aid for antidepressant use during pregnancy.
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CLINICAL_TRIALS trial_result · 2017-05-12Clinical Trial Update: A Study of Diagnosis and Treatment of Depression Based on Biological Evidence of Dopamine Reward Pathway [Phase 4]
This document provides an update on a Phase 4 clinical study evaluating diagnosis and treatment of depression based on biological evidence r…
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CLINICAL_TRIALS trial_result · 2017-05-12Clinical Trial Update: Mother Matters Online Postpartum Support [NA]
Clinical trial update indicating completion of the Mother Matters Online Postpartum Support program study, which targeted depression.
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CLINICAL_TRIALS trial_result · 2017-05-10Clinical Trial Update: Pioglitazone in Patients With Mood Disorders [Phase 4]
A Phase 4 clinical trial evaluated pioglitazone in patients with mood disorders, including major depressive disorder and insulin resistance.…
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FDA approval · 2017-05-09FDA Approved: QUETIAPINE FUMARATE — Original Application (Accord Healthcare Inc.)
FDA approved Accord Healthcare's generic quetiapine fumarate under Original Application (ANDA090681) to bring a quetiapine fumarate product …
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CLINICAL_TRIALS trial_result · 2017-05-09Clinical Trial Update: Stepped Care for Depression and Musculoskeletal Pain [Phase 4]
Phase 4 trial update on a stepped-care approach for depression and musculoskeletal pain; results have been posted.
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CLINICAL_TRIALS trial_result · 2017-05-09Clinical Trial Update: Vilazodone for Treatment of Geriatric Depression [Phase 4]
Phase 4 trial update evaluating vilazodone for geriatric depression (major depressive disorder); study completed with results posted on 2017…
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CLINICAL_TRIALS trial_result · 2017-05-08Clinical Trial Update: Rapid Antidepressant Effects of ATP and Phosphocreatine [Phase 2]
This clinical trial update describes a Phase 2 study evaluating whether ATP and phosphocreatine can produce rapid antidepressant effects in …
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CLINICAL_TRIALS trial_result · 2017-05-05Clinical Trial Update: Double-blind Pilot Trial of Mirtazapine for the Treatment of Co-occurring AD/MDD. [Phase 2]
A double-blind Phase 2 pilot trial evaluated mirtazapine for co-occurring Major Depressive Disorder and Alcohol Use Disorder. The study has …