Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-10-04Clinical Trial Update: Does Dual Therapy Hasten Antidepressant Response? [Phase 4]
Phase 4 clinical trial assessing whether dual therapy accelerates antidepressant response in major depressive disorder; results posted after…
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CLINICAL_TRIALS trial_result · 2017-10-02Clinical Trial Update: Adjunctive Vitamin D in the Treatment of Non-remitted Depression [Phase 3]
Phase 3 trial of adjunctive vitamin D for non-remitted depression was terminated.
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CLINICAL_TRIALS trial_result · 2017-10-02Clinical Trial Update: An Efficacy and Safety Study of Escitalopram Long-Term Treatment in Major Depressive Disorder With Associated Anxiety Symptoms [Phase 4]
Phase 4 clinical trial update evaluating long-term efficacy and safety of escitalopram in major depressive disorder with associated anxiety …
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CLINICAL_TRIALS trial_result · 2017-10-02Clinical Trial Update: Using Peer Mentors to Deliver Depression Care [NA]
Clinical trial evaluating peer mentors to deliver depression care has completed; results posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-09-29Clinical Trial Update: Peer to Peer Delivery of Behavioral Activation [NA]
Clinical trial completed assessing peer-to-peer delivery of behavioral activation for depression; results posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-09-28Clinical Trial Update: A Study of Intermittent Doses of CERC-301 in MDD [Phase 2]
Phase 2 trial updating intermittent dosing of CERC-301 in major depressive disorder has completed.
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CLINICAL_TRIALS trial_result · 2017-09-28Clinical Trial Update: Effectiveness Trial of the French Blues Indicated Depression Prevention Program [Phase 4]
Phase 4 effectiveness trial update for the French Blues indicated depression prevention program shows completed status.
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FDA approval · 2017-09-26FDA Approved: BUPROPION HYDROCHLORIDE — Supplemental Application (Amneal Pharmaceuticals of New York LLC)
FDA approved a supplemental application for a generic Bupropion hydrochloride product from Amneal Pharmaceuticals of New York LLC.
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FDA approval · 2017-09-26FDA Approved: QUETIAPINE FUMARATE — Supplemental Application (Sun Pharmaceutical Industries, Inc.)
FDA approved a supplemental application for quetiapine fumarate from Sun Pharmaceutical Industries, Inc., approving updates to the generic's…
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FDA approval · 2017-09-26FDA Approved: QUETIAPINE FUMARATE — Supplemental Application (Aurobindo Pharma Limited)
FDA approved a supplemental application to market a generic quetiapine fumarate product from Aurobindo Pharma Limited.
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CLINICAL_TRIALS trial_result · 2017-09-25Clinical Trial Update: Effect of Amygdala Neurofeedback on Depressive Symptoms and Processing Biases [NA]
A completed clinical trial assessing the effect of amygdala neurofeedback on depressive symptoms and processing biases in individuals with m…
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CLINICAL_TRIALS trial_result · 2017-09-25Clinical Trial Update: A One Year Open Label Study Assessing the Safety and Tolerability of Vilazodone in Patients With Major Depressive Disorder (MDD) [Phase 3]
Phase 3 open-label study assessing safety and tolerability of vilazodone in major depressive disorder completed with results posted.
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CLINICAL_TRIALS trial_result · 2017-09-18Clinical Trial Update: Epidural Cortical Stimulation for Depression [NA]
This clinical trial update notes that results for epidural cortical stimulation in treatment-resistant depression were posted in 2017. The s…
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CLINICAL_TRIALS trial_result · 2017-09-14Clinical Trial Update: Comparison of Venlafaxine and Fluoxetine in the Treatment of Postmenopausal Women With Major Depression [Phase 4]
Phase 4 trial comparing venlafaxine to fluoxetine in postmenopausal women with major depression completed.
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CLINICAL_TRIALS trial_result · 2017-09-12Clinical Trial Update: Glutamatergic and GABAergic Mediators of Antidepressant Response in Major Depression [Phase 4]
Phase 4 trial update evaluating glutamatergic and GABAergic mediators of antidepressant response in major depression, completed with posted …
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CLINICAL_TRIALS trial_result · 2017-09-12Clinical Trial Update: A Randomized, Double-Blind, Parallel-Group, Placebo-Controlled, Fixed Dose Study Evaluating the Efficacy and Safety of Orvepitant in Subjects With Major Depressive Disorder [Phase 2]
Phase 2 trial evaluating orvepitant for major depressive disorder was terminated; results posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-09-11Clinical Trial Update: Memory Flexibility Training for Depression [Phase 1, Phase 2]
A clinical trial update on memory flexibility training for major depressive disorder, covering Phase 1 and Phase 2, with completed status.
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CLINICAL_TRIALS trial_result · 2017-09-11Clinical Trial Update: Major Depressive Disorder Study In Adults [Phase 4]
Phase 4 trial update for adults with Major Depressive Disorder. The study has completed.
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FDA approval · 2017-09-08FDA Approved: TRAZODONE HYDROCHLORIDE — Original Application (Accord Healthcare, Inc.)
FDA approved Accord Healthcare's original application for trazodone hydrochloride tablets, establishing a generic version of trazodone hydro…
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CLINICAL_TRIALS trial_result · 2017-09-01Clinical Trial Update: The Neurobiology of Approach Avoidance Training in Depression [NA]
A UC San Diego study investigates the neurobiology of approach-avoidance training in Major Depressive Disorder and has completed.
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CLINICAL_TRIALS trial_result · 2017-09-01Clinical Trial Update: TMS Treatment for Depression in the National Health Service [NA]
A NHS-based clinical trial evaluating transcranial magnetic stimulation (TMS) for depression has completed.
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CLINICAL_TRIALS trial_result · 2017-08-31Clinical Trial Update: Effectiveness Study of Mirtazapine Combined With Paroxetine in Major Depressive Patients Without Early Improvement [Phase 4]
An update on a Phase 4 study evaluating the effectiveness of combining mirtazapine with paroxetine in adults with major depressive disorder …
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CLINICAL_TRIALS research · 2017-08-31Clinical Trial Update: Deep-brain Magnetic Stimulation (DMS) in the Treatment of Major Depressive Disorder [NA]
Clinical trial update indicating completion of a study evaluating Deep-brain Magnetic Stimulation for major depressive disorder.
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CLINICAL_TRIALS trial_result · 2017-08-29Clinical Trial Update: Enhancing Outcomes, Reducing Costs: Evaluating Peer Support for Mood Disorders
A completed clinical trial from Massachusetts General Hospital evaluating the effectiveness and cost impact of peer support for mood disorde…
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CLINICAL_TRIALS trial_result · 2017-08-29Clinical Trial Update: Out-patient Wake Therapy, Light Therapy and Sleep Phase Advance for Depression [NA]
This document reports a completed clinical trial evaluating non-pharmacologic therapies—out-patient wake therapy, light therapy, and sleep p…