Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-02-28Clinical Trial Update: Pharmacovigilance in Gerontopsychiatric Patients [Phase 3]
A Phase 3 pharmacovigilance trial in gerontopsychiatric patients has been terminated; the study focused on dementia and depression with rela…
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CLINICAL_TRIALS withdrawal · 2018-02-28Clinical Trial Update: Using the LENA System in Early Intervention [NA]
The UNC Chapel Hill–sponsored trial evaluating the LENA System in early intervention for depression has been withdrawn.
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CLINICAL_TRIALS trial_result · 2018-02-27Clinical Trial Update: Study of Neuroplasticity on Depressed Patients : Modulation of MEP Induced by Theta Burst Stimulation [NA]
A completed clinical trial studied neuroplasticity in patients with major depressive disorder by modulating motor-evoked potentials with The…
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CLINICAL_TRIALS trial_result · 2018-02-23Clinical Trial Update: Study of Ibuprofen Effects on Brain Function [Phase 2, Phase 3]
A Phase 2/Phase 3 study evaluating ibuprofen effects on brain function in adults with major depressive disorder has completed and posted res…
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CLINICAL_TRIALS trial_result · 2018-02-19Clinical Trial Update: Antidepressant Treatment at an Inner City Asthma Clinic [Phase 4]
Phase 4 trial update on antidepressant treatment for patients with depression at an inner-city asthma clinic; the study has completed and re…
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CLINICAL_TRIALS trial_result · 2018-02-15Clinical Trial Update: Omega-3 Fatty Acids in Adolescent Depression [Phase 2]
A Phase 2 trial evaluating omega-3 fatty acids for adolescent depression has completed, with results posted February 2018.
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CLINICAL_TRIALS trial_result · 2018-02-15Clinical Trial Update: Effects of Low Dose Ketamine Given at Induction of Anesthesia on Postoperative Mood in Patients With Depressive Symptoms [NA]
A terminated clinical trial evaluating whether low-dose ketamine given at induction of anesthesia affects postoperative mood in patients wit…
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CLINICAL_TRIALS trial_result · 2018-02-15Clinical Trial Update: Efficacy of Extended-release Quetiapine (Seroquel XR) as Adjunctive Therapy to Cognitive Behavioral Therapy in the Treat [NA]
Clinical trial assessing extended-release quetiapine as an adjunct to cognitive behavioral therapy for major depressive disorder and general…
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CLINICAL_TRIALS trial_result · 2018-02-14Clinical Trial Update: Ketamine as a Rapid Treatment for Post-traumatic Stress Disorder (PTSD) [Phase 2]
Phase 2 clinical trial investigating ketamine as a rapid-acting treatment for post-traumatic stress disorder (PTSD) has completed and result…
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CLINICAL_TRIALS trial_result · 2018-02-08Clinical Trial Update: Efficacy and Tolerability of Riluzole in Treatment Resistant Depression [Phase 2]
Phase 2 clinical trial update on riluzole for treatment-resistant depression, reporting efficacy and tolerability with completed results.
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CLINICAL_TRIALS trial_result · 2018-02-07Clinical Trial Update: The Effectiveness of rTMS in Depressed VA Patients [NA]
This clinical trial update reports results from a completed VA study evaluating the effectiveness of repetitive transcranial magnetic stimul…
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FDA approval · 2018-02-06FDA Approved: PRISTIQ EXTENDED-RELEASE — Supplemental Application (Wyeth Pharmaceuticals LLC, a subsidiary of Pfizer Inc.)
FDA approved a supplemental NDA for PRISTIQ EXTENDED-RELEASE (desvenlafaxine succinate) from Wyeth Pharmaceuticals (Pfizer), approving the e…
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CLINICAL_TRIALS trial_result · 2018-02-06Clinical Trial Update: Attachment Based Family Therapy for Suicidal Adolescents [NA]
Completed clinical trial evaluating Attachment Based Family Therapy for suicidal adolescents; results posted in 2018.
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CLINICAL_TRIALS research · 2018-02-05Clinical Trial Update: 5 Alpha Reductase Inhibitors And The Risk Of Suicide And Depression
A completed clinical trial evaluating the risk of suicide and depression with 5-alpha-reductase inhibitors in cases related to benign prosta…
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CLINICAL_TRIALS trial_result · 2018-01-31Clinical Trial Update: Medication Treatment for Depression in Nursing Home Residents
A completed clinical trial investigating medication treatment for depression in nursing home residents; results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-01-31Clinical Trial Update: Venlafaxine for Depression in Alzheimer's Disease (DIADs-3) [NA]
Clinical trial update for venlafaxine in Alzheimer's disease with comorbid depression; study completed and results posted.
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CLINICAL_TRIALS trial_result · 2018-01-30Clinical Trial Update: Chronic Kidney Disease Antidepressant Sertraline Trial [Phase 3]
A Phase 3 trial evaluating sertraline for depression in adults with chronic kidney disease has completed, with results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-01-30Clinical Trial Update: Assessment in Work Productivity and the Relationship With Cognitive Symptoms in Patients With MDD Taking Vortioxetine [Phase 4]
Phase 4 trial assessing work productivity and cognitive symptoms in patients with major depressive disorder treated with vortioxetine.
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CLINICAL_TRIALS trial_result · 2018-01-29Clinical Trial Update: Therapy for Depressed Elders With Thought Problems [Phase 3]
Phase 3 trial update for a therapy aimed at depression in elderly with cognitive problems; study completed.
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CLINICAL_TRIALS trial_result · 2018-01-18Clinical Trial Update: The Effects of Dopamine on Reward Processing [Phase 1]
Phase 1 trial examining the effects of dopamine on reward processing in adults with major depressive disorder has completed; results were po…
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CLINICAL_TRIALS trial_result · 2018-01-16Clinical Trial Update: Using Affective Differences to Predict Response to Behavioral Treatment for Major Depressive Disorder
This clinical trial update reports on using affective differences to predict how people with major depressive disorder respond to behavioral…
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CLINICAL_TRIALS trial_result · 2018-01-12Clinical Trial Update: Comparison of Anodal Transcranial Direct Current Stimulation (t-DCS) and Sham Stimulation in Patients With Treatment-resistant Depression [Phase 4]
A Phase 4 clinical trial comparing anodal t-DCS to sham in treatment-resistant depression has completed.
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CLINICAL_TRIALS trial_result · 2018-01-10Clinical Trial Update: Mobile Mindfulness to Improve Psychological Distress After Critical Illness [NA]
A completed study evaluating mobile mindfulness to reduce psychological distress in individuals after critical illness, with results posted …
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CLINICAL_TRIALS trial_result · 2018-01-08Clinical Trial Update: CBT for Adherence and Depression in Diabetes [NA]
A completed clinical trial evaluating cognitive-behavioral therapy for adherence and depression in patients with diabetes and co-morbid depr…
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CLINICAL_TRIALS trial_result · 2018-01-08Clinical Trial Update: Investigating Transcranial Ultrasound as a Potential Intervention for Depression [NA]
Completed clinical trial investigating transcranial ultrasound as an intervention for depression and anxiety disorders; results posted in 20…