Major Depressive Disorder
📧 Sign up to get email alerts when something new happens for Major Depressive Disorder.
Sign up freeTop drugs studied for this disease
-
FDA label_change · 2023-10-10FDA Approved: BUPROPION HYDROCHLORIDE — Supplemental Application (Apnar Pharma LP)
The FDA approved a supplemental application for bupropion hydrochloride from Apnar Pharma LP, indicating an approved change to an existing p…
-
FDA approval · 2023-10-06FDA Approved: IMIPRAMINE HYDROCHLORIDE — Supplemental Application (Leading Pharma, LLC)
The FDA approved a supplemental application for imipramine hydrochloride from Leading Pharma, LLC under the ANDA process.
-
CLINICAL_TRIALS trial_result · 2023-10-06Clinical Trial Update: Transcranial Direct Current Stimulation for the Treatment of Deficits After Traumatic Brain Injury [NA]
Clinical trial update for transcranial direct current stimulation in traumatic brain injury and related symptoms; status completed with resu…
-
CLINICAL_TRIALS trial_result · 2023-10-05Clinical Trial Update: Intraoperative Ketamine Versus Saline in Depressed Patients Undergoing Anesthesia for Non-cardiac Surgery [Phase 4]
Phase 4 trial comparing intraoperative ketamine to saline in depressed patients undergoing non-cardiac surgery; results have been posted aft…
-
CLINICAL_TRIALS trial_result · 2023-10-02Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Fremanezumab for Preventive Treatment of Migraine in Patients With Major Depressive Disorder [Phase 4]
Phase 4 trial evaluating fremanezumab for preventative treatment of migraine in patients with major depressive disorder has completed; resul…
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
CLINICAL_TRIALS trial_result · 2023-10-02Clinical Trial Update: PEA vs. Placebo for Major Depression [Phase 2]
Phase 2 clinical trial evaluating PEA versus placebo for major depression, with bipolar depression and major depressive disorder as conditio…
-
CLINICAL_TRIALS trial_result · 2023-10-02Clinical Trial Update: Stress and Inflammation in Late-Life Depression [Phase 4]
Phase 4 clinical trial update on stress and inflammation in late-life depression has completed with results posted.
-
CLINICAL_TRIALS trial_result · 2023-09-28Clinical Trial Update: A Study of SLS-002 (Intranasal Racemic Ketamine) in Adults With Major Depressive Disorder at Imminent Risk of Suicide [Phase 2]
Phase 2 clinical trial of intranasal racemic ketamine (SLS-002) in adults with major depressive disorder at imminent risk of suicide has com…
-
CLINICAL_TRIALS trial_result · 2023-09-28Clinical Trial Update: A Cariprazine Study in the Prevention of Relapse in Bipolar I Disorder Patients Whose Current Episode is Manic or Depressive, With or Without Mixed Features [Phase 3]
A Phase 3 trial evaluating cariprazine for preventing relapse in Bipolar I Disorder patients currently in manic or depressive episodes (with…
-
CLINICAL_TRIALS trial_result · 2023-09-28Clinical Trial Update: Ketamine or Placebo in Patients With Major Depression and Advanced Cancer [Phase 1, Phase 2]
A clinical trial evaluating ketamine versus placebo for major depression in patients with advanced cancer has completed Phase 1 and Phase 2.
-
FDA approval · 2023-09-22FDA Approved: EXXUA — Original Application (Aytu Therapeutics, LLC)
The FDA approved EXXUA (gepirone) as a new drug for major depressive disorder.
-
FDA approval · 2023-09-22FDA Approved: SERTRALINE HYDROCHLORIDE — Supplemental Application (Granules Pharmaceuticals Inc.)
FDA approved a supplemental application for sertraline hydrochloride from Granules Pharmaceuticals Inc. The action confirms continued approv…
-
CLINICAL_TRIALS trial_result · 2023-09-22Clinical Trial Update: The Effect of Probiotics on Depression Syndrome and Risk Factors of Cardiovascular Disease in Hemodialysis Patients [Phase 4]
Phase 4 trial evaluating the effect of probiotics on depression symptoms and cardiovascular risk factors in hemodialysis patients has been c…
-
CLINICAL_TRIALS trial_result · 2023-09-21Clinical Trial Update: Chronic Sleep Deprivation Among the Poor: A Lab-in-the-field Approach [NA]
Completed clinical trial investigating chronic sleep deprivation effects on blood pressure and depression; results posted.
-
CLINICAL_TRIALS trial_result · 2023-09-21Clinical Trial Update: Effects of Erythropoietin for Cognitive Side-effects of ECT [Phase 2]
Phase 2 trial evaluating erythropoietin for cognitive side-effects associated with electroconvulsive therapy; study completed.
-
FDA approval · 2023-09-21FDA Approved: CLOMIPRAMINE HYDROCHLORIDE — Supplemental Application (Lifestar Pharma LLC)
FDA approved a supplemental application for clomipramine hydrochloride from Lifestar Pharma LLC, resulting in a generic version of the antid…
-
FDA approval · 2023-09-19FDA Approved: FLUOXETINE — Supplemental Application (Aurobindo Pharma Limited)
The FDA approved a supplemental application for fluoxetine submitted by Aurobindo Pharma Limited. This action updates the regulatory status …
-
FDA approval · 2023-09-19FDA Approved: QUETIAPINE FUMARATE — Supplemental Application (Accord Healthcare Inc.)
FDA approves Accord Healthcare's supplemental application to market quetiapine fumarate as a generic drug.
-
CLINICAL_TRIALS trial_result · 2023-09-18Clinical Trial Update: Open Label Ketamine Treatment for Major Depressive Disorder in Veterans [Phase 2]
Phase 2 open-label trial evaluating ketamine treatment for major depressive disorder in veterans has completed.
-
CLINICAL_TRIALS trial_result · 2023-09-15Clinical Trial Update: C-STRESS: A Mental Health App for College Students With Depression [EARLY_Phase 1]
Early-phase trial updates for a mental health app (C-STRESS) targeting college students with depression and anxiety; study terminated per re…
-
CLINICAL_TRIALS trial_result · 2023-09-14Clinical Trial Update: Major Depressive Disorder - Understanding The Link Between The Brain And The Heart [Phase 4]
Phase 4 clinical trial exploring connections between brain and heart in major depressive disorder has completed.
-
CLINICAL_TRIALS trial_result · 2023-09-14Clinical Trial Update: An Expanded Access Protocol for Esketamine Treatment in Participants With Treatment Resistant Depression (TRD) Who do Not Have Other Treatment Alternatives [Phase 3]
Expanded access protocol for esketamine in treatment-resistant depression completed.
-
CLINICAL_TRIALS trial_result · 2023-09-06Clinical Trial Update: Enhancing Well-Being Through Exercise During Old Age [NA]
A completed clinical trial investigating how exercise affects well-being in older adults with depression and osteoarthritis; results posted …
-
CLINICAL_TRIALS trial_result · 2023-09-01Clinical Trial Update: Ketamine Versus Electroconvulsive Therapy in Depression [Phase 3]
Phase 3 trial comparing Ketamine to Electroconvulsive Therapy for depression is suspended.
-
CLINICAL_TRIALS trial_result · 2023-08-28Clinical Trial Update: Trial to Test Effectiveness of Depression Intervention for Mistreated Older Adults [NA]
Completed clinical trial assessing a depression intervention for mistreated older adults; results posted in 2023.