Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2024-05-06Clinical Trial Update: Cognitive-Behavioral Therapy With Exercise Training in Adolescent Females With Elevated Depression Symptoms [NA]
This clinical trial is evaluating cognitive-behavioral therapy combined with exercise training for adolescent females with elevated depressi…
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CLINICAL_TRIALS trial_result · 2024-05-03Clinical Trial Update: A Trial of Online LGBTQ-affirmative Cognitive Behavioral Therapy to Reduce Depression and Associated Health Risks Among Young Adults [NA]
A completed clinical trial evaluated an online LGBTQ-affirmative cognitive behavioral therapy program to reduce depression and related healt…
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CLINICAL_TRIALS research · 2024-05-03Clinical Trial Update: Attachment Style and Reflective Functioning in CBASP [NA]
A completed clinical trial update examining attachment style and reflective functioning in CBASP for major depressive disorder.
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CLINICAL_TRIALS research · 2024-05-03Clinical Trial Update: Promoting Sustainable Return to Work Among Employees on Sick Leave Due to a Mental Health Condition: Evaluation of the HealthyMinds Online Group Intervention [NA]
A clinical trial evaluating the HealthyMinds Online Group Intervention to help employees on sick leave due to mental health conditions retur…
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CLINICAL_TRIALS withdrawal · 2024-05-03Clinical Trial Update: First-In-Human (FIH), Single Ascending Dose (SAD) Study of FluoroEthylNorMemantine (FENM) [Phase 1]
The first-in-human single ascending dose study of FluoroEthylNorMemantine (FENM) by ReST Therapeutics has been withdrawn; the listed conditi…
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CLINICAL_TRIALS trial_result · 2024-05-02Clinical Trial Update: Activating and Connecting Teens (ACT) Study [NA]
The Activating and Connecting Teens (ACT) study examining depression in adolescents has completed. Results were posted on 2024-05-02.
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FDA approval · 2024-05-02FDA Approved: FLUOXETINE — Supplemental Application (Aurobindo Pharma Limited)
The FDA approved a supplemental application for the generic fluoxetine from Aurobindo Pharma Limited (ANDA213265).
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CLINICAL_TRIALS research · 2024-05-02Clinical Trial Update: Adaptive Stress Response: The Hot Yoga Study [NA]
This clinical trial update reports the completion of a study on adaptive stress response using hot yoga, investigating effects on inflammati…
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CLINICAL_TRIALS research · 2024-05-02Clinical Trial Update: Physical Exercise for Treatment of Depression and Anxiety - RCT [NA]
Clinical trial update on a randomized controlled trial examining physical exercise as a treatment for depression and anxiety; the study stat…
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CLINICAL_TRIALS trial_result · 2024-05-01Clinical Trial Update: Development of Pregnenolone as a Treatment for Depression [Phase 1]
A Phase 1 clinical trial evaluating pregnenolone for major depressive disorder has been completed and results were posted in May 2024.
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CLINICAL_TRIALS research · 2024-05-01Clinical Trial Update: aiTBS for Relieving NSSI in Depressive Patients [NA]
ClinicalTrials.gov update describing a recruiting study evaluating accelerated intermittent theta-burst stimulation (aiTBS) to relieve non-s…
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CLINICAL_TRIALS trial_result · 2024-04-30Clinical Trial Update: Designing an Implementation Strategy for Delivering Routine Mental Health Screening and Treatment [NA]
A terminated clinical trial evaluated an implementation strategy for delivering routine mental health screening and treatment for patients w…
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CLINICAL_TRIALS research · 2024-04-30Clinical Trial Update: Exergames-acceptance and Commitment Therapy Program for Treatment of Major Depressive Disorder [NA]
A clinical trial investigating an exergames-acceptance and commitment therapy program for treating major depressive disorder; the study is c…
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CLINICAL_TRIALS trial_result · 2024-04-30Clinical Trial Update: Transcranial Direct Current Stimulation (tDCS) Therapy in Major Depression [NA]
Completed clinical trial evaluating transcranial direct current stimulation (tDCS) for major depressive disorder. The update summarizes safe…
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CLINICAL_TRIALS trial_result · 2024-04-30Clinical Trial Update: Cytokine-Induced Transcription in Depressed Inpatients Undergoing Psychotherapy
This entry reports a completed clinical trial investigating cytokine-induced transcription in depressed inpatients undergoing psychotherapy.
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CLINICAL_TRIALS research · 2024-04-30Clinical Trial Update: Clinical, Cognitive and Neural Effects of Potentiation of ECT by rTMS in Treatment-Resistant Depression [NA]
An upcoming clinical trial will evaluate whether potentiating electroconvulsive therapy (ECT) with repetitive transcranial magnetic stimulat…
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CLINICAL_TRIALS trial_result · 2024-04-30Clinical Trial Update: ALTO-300 in Depression [Phase 2]
ALTO-300's Phase 2 trial for Major Depressive Disorder has completed. The update does not include results in the provided snippet.
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CLINICAL_TRIALS research · 2024-04-30Clinical Trial Update: Reaching Out to Distressed Medical Residents, Fellows and Faculty [NA]
This entry notes an ongoing clinical trial hosted by Oregon Health and Science University to support distressed medical residents, fellows, …
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CLINICAL_TRIALS research · 2024-04-30Clinical Trial Update: Accelerated Intermittent Theta-Burst Stimulation (aiTBS) in Treatment-Resistant Depression of Bipolar II Disorder [NA]
Clinical trial evaluating accelerated intermittent theta-burst stimulation as a treatment for treatment-resistant depression in Bipolar II d…
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CLINICAL_TRIALS trial_result · 2024-04-29Clinical Trial Update: A Long-Term Study of Brexpiprazole in Patients With Major Depressive Disorder [Phase 3]
A Phase 3 long-term study of brexpiprazole in adults with major depressive disorder has completed, with results posted in April 2024.
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CLINICAL_TRIALS trial_result · 2024-04-29Clinical Trial Update: Efficacy and Safety of Toludesvenlafaxine Hydrochloride Sustained-release Tablets Versus Desvenlafaxine Succinate Sustained-release Tablets Targeting Anhedonia in Patients With Major Depression Disorder [NA]
This clinical trial compares toludesvenlafaxine hydrochloride sustained-release tablets against desvenlafaxine succinate sustained-release t…
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CLINICAL_TRIALS research · 2024-04-29Clinical Trial Update: Online Brief CBT Intervention for Women With PCOS [NA]
This is an update on a clinical trial evaluating an online brief CBT intervention for women with polycystic ovary syndrome with depressive a…
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CLINICAL_TRIALS trial_result · 2024-04-26Clinical Trial Update: ALTO-300 in Depression (ALTO-300-004) [Phase 2]
ALTO-300-004, a Phase 2 trial in Major Depressive Disorder, has completed enrollment and its study status.
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CLINICAL_TRIALS research · 2024-04-26Clinical Trial Update: A Scalable Psychological Intervention to Reduce Psychological Distress Among Workers of Assisted Living Facilities [NA]
This clinical trial update describes a scalable psychological intervention aimed at reducing depression, anxiety, and psychological distress…
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CLINICAL_TRIALS research · 2024-04-25Clinical Trial Update: Thoughts and Health - Preventing Depression in Adolescents [NA]
A Vastra Gotaland Region-sponsored clinical trial aimed at preventing depression in adolescents is currently recruiting.