Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2024-08-02Clinical Trial Update: Using Electrophysiology to Index Non-invasive Brain Stimulation Effects on Reward System Functioning in Depression [NA]
This clinical trial investigates how electrophysiology can index the effects of non-invasive brain stimulation on reward system functioning …
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CLINICAL_TRIALS research · 2024-08-02Clinical Trial Update: The Cerebral and Cognitive Changes After Intermittent Theta Burst Stimulation (iTBS) Treatment for Depression [NA]
An ongoing clinical trial is evaluating cerebral and cognitive changes after intermittent theta burst stimulation for depression, currently …
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CLINICAL_TRIALS trial_result · 2024-08-01Clinical Trial Update: Symptom-specific TMS Targets for Depression and Anxiety [Phase 2]
Phase 2 trial updating on symptom-specific transcranial magnetic stimulation targets for depression and anxiety has completed.
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CLINICAL_TRIALS trial_result · 2024-08-01Clinical Trial Update: Online and Shared Decision-Making Interventions to Engage Service Men and Women in Post-Deployment Mental Health Care [NA]
Completed clinical trial evaluating online and shared decision-making interventions to engage service members in post-deployment mental heal…
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CLINICAL_TRIALS trial_result · 2024-08-01Clinical Trial Update: Transcranial Direct Current Stimulation Therapy for Major Depression [NA]
A completed clinical trial from the University of East London evaluating transcranial direct current stimulation for Major Depressive Disord…
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CLINICAL_TRIALS research · 2024-08-01Clinical Trial Update: A Novel Individualized Connectome-guided Approach for Precision Intermittent Theta Burst Stimulation for Depression [NA]
This entry describes an ongoing clinical trial at the Institute of Mental Health, Singapore evaluating a personalized connectome-guided inte…
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CLINICAL_TRIALS trial_result · 2024-07-31Clinical Trial Update: Study to Evaluate the Efficacy and Safety of Once-Weekly Oral NBI-1065846 in the Treatment of Anhedonia in MDD [Phase 2]
Phase 2 trial evaluating the efficacy and safety of once-weekly oral NBI-1065846 for anhedonia in major depressive disorder has completed, w…
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CLINICAL_TRIALS trial_result · 2024-07-31Clinical Trial Update: Integrating a Suite of Mental Health Apps for Depression in a Healthcare Setting [NA]
A completed clinical trial evaluated integrating a suite of mental health apps for depression and anxiety in a healthcare setting.
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CLINICAL_TRIALS trial_result · 2024-07-31Clinical Trial Update: A Trial to Assess a Wearable Patch's Functioning to Detect Medication Ingestion [NA]
This clinical trial update reports on a completed study evaluating a wearable patch's ability to detect medication ingestion in people with …
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CLINICAL_TRIALS trial_result · 2024-07-31Clinical Trial Update: New Moms Mood Tracking & Wellbeing [NA]
The UCLA-sponsored clinical trial New Moms Mood Tracking & Wellbeing (NCT05056454) has completed; the update does not report trial results.
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CLINICAL_TRIALS research · 2024-07-30Clinical Trial Update: Process-based Therapy for Difficult-to-treat Anxiety Disorders and Depression [NA]
Goethe University is conducting a clinical trial of a process-based therapy for depression and anxiety disorders, and the study is currently…
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FDA approval · 2024-07-29FDA Approved: CITALOPRAM — Supplemental Application (Aurobindo Pharma Limited)
FDA approved a supplemental application for a citalopram hydrobromide product manufactured by Aurobindo Pharma Limited.
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CLINICAL_TRIALS trial_result · 2024-07-29Clinical Trial Update: Establishing Efficacy of a Functional-Restoration Based CAM Pain Management Program in Post-9/11 Veterans [NA]
A clinical trial examined the efficacy of a functional-restoration based CAM pain management program in post-9/11 veterans with chronic pain…
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CLINICAL_TRIALS trial_result · 2024-07-29Clinical Trial Update: Collaborative Stepped Care and Peer Support Programme for Older People At-Risk of or With Depression [NA]
A completed clinical trial evaluating a collaborative stepped care and peer-support program for older adults at risk of or with depression.
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CLINICAL_TRIALS trial_result · 2024-07-26Clinical Trial Update: Sleep Modulation as Antidepressant Randomized Trial [NA]
A completed randomized trial evaluating sleep modulation as an antidepressant strategy in participants with depression.
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CLINICAL_TRIALS research · 2024-07-25Clinical Trial Update: Combining mHealth and Nurse-delivered Care to Improve the Outcomes of People With Serious Mental Illness in West Africa [NA]
This clinical trial update describes a study combining mobile health tools with nurse-delivered care to improve outcomes for people with ser…
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FDA approval · 2024-07-25FDA Approved: DOXEPIN — Original Application (Aurobindo Pharma Limited)
FDA approved the original ANDA for doxepin from Aurobindo Pharma Limited, granting approval for a generic doxepin product.
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CLINICAL_TRIALS trial_result · 2024-07-25Clinical Trial Update: Augmenting Internet-Based Cognitive Behavioral Therapy for Major Depressive Disorder With Low-Level Light Therapy [NA]
A terminated clinical trial evaluated whether adding low-level light therapy to internet-based cognitive behavioral therapy affects outcomes…
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CLINICAL_TRIALS withdrawal · 2024-07-25Clinical Trial Update: Psilocybin for Major Depressive Disorder [Phase 2]
Phase 2 study evaluating psilocybin for Major Depressive Disorder has been withdrawn.
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CLINICAL_TRIALS trial_result · 2024-07-24Clinical Trial Update: e-Mindfulness for Depression in Older Adults [NA]
The document notes the completion of a clinical trial evaluating e-Mindfulness for depression in older adults, sponsored by Washington Unive…
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CLINICAL_TRIALS trial_result · 2024-07-23Clinical Trial Update: 5-HTP and Creatine for Depression [Phase 2]
A Phase 2 study investigating the combination of 5-HTP and creatine for major depressive disorder has completed enrollment and posted result…
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CLINICAL_TRIALS research · 2024-07-23Clinical Trial Update: A Biological Signature for the Early Differential Diagnosis of Psychosis
This clinical trial update describes a study to identify a biological signature for early differential diagnosis of psychosis, including sch…
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CLINICAL_TRIALS research · 2024-07-23Clinical Trial Update: Sleep Modulation to Treat Depression [NA]
This clinical trial update describes a study on sleep modulation as a potential treatment for Major Depressive Disorder, currently recruitin…
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CLINICAL_TRIALS trial_result · 2024-07-22Clinical Trial Update: Outcomes of a Self-guided Versus Therapist-guided Online Mental Health Treatment [NA]
A completed clinical trial by Duke University comparing self-guided versus therapist-guided online treatment for depression and anxiety, rep…
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CLINICAL_TRIALS research · 2024-07-22Clinical Trial Update: Effect of Esketamine on Postoperative Depression、Gut Microbiota、Bispectral Index Data of Depression Patients Undergoing Breast Cancer Operation (ESPOD-BI) [Phase 4]
Phase 4 study ESPOD-BI assesses esketamine's impact on postoperative depression, gut microbiota changes, and BIS readings in patients with d…