Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS withdrawal · 2023-04-24Clinical Trial Update: Neurobiology of Treatment Responses in MDD [Phase 3]
A Phase 3 clinical trial for major depressive disorder has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2023-04-03Clinical Trial Update: A Comparative Trial of TMS Approaches to Treating Depression [Phase 4]
Clinical trial in Phase 4 comparing transcranial magnetic stimulation approaches for depression was withdrawn.
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CLINICAL_TRIALS withdrawal · 2023-02-09Clinical Trial Update: Optimal Duration of Olanzapine Add-on Therapy in Major Depression [Phase 3]
A Phase 3 trial evaluating the optimal duration of add-on olanzapine therapy in major depressive disorder was withdrawn.
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CLINICAL_TRIALS withdrawal · 2023-01-30Clinical Trial Update: Open-label Brexpiprazole fMRI Trial in Adults With Major Depressive Disorder and Anxiety [Phase 4]
Open-label Phase 4 trial of brexpiprazole in adults with major depressive disorder and anxiety was withdrawn.
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CLINICAL_TRIALS withdrawal · 2022-11-29Clinical Trial Update: Vortioxetine Monotherapy for Major Depressive Disorder in Type 2 Diabetes [Phase 4]
A Phase 4 trial of vortioxetine monotherapy for major depressive disorder in patients with type 2 diabetes was withdrawn.
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CLINICAL_TRIALS withdrawal · 2022-08-05Clinical Trial Update: ECT vs. Esketamine [Phase 3]
A Phase 3 clinical trial comparing electroconvulsive therapy (ECT) versus esketamine for treatment resistant depression and major depressive…
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CLINICAL_TRIALS withdrawal · 2021-08-20Clinical Trial Update: Study Evaluating Effexor XR in Chinese Subjects With Major Depressive Disorder [Phase 4]
Phase 4 trial evaluating Effexor XR in Chinese subjects with major depressive disorder has been withdrawn.
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EMA withdrawal · 2021-06-22EMA Withdrawn: Nodetrip (previously Xeristar) (duloxetine) — Esteve Pharmaceuticals, S.A.
The EMA has withdrawn Nodetrip (duloxetine) from Esteve Pharmaceuticals, covering indications in anxiety disorders, major depressive disorde…
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CLINICAL_TRIALS withdrawal · 2020-10-19Clinical Trial Update: Leveraging EEG for Antidepressant Prediction With Duloxetine and Bupropion [Phase 4]
Phase 4 trial exploring EEG-based prediction for antidepressant response with duloxetine and bupropion was withdrawn.
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CLINICAL_TRIALS withdrawal · 2020-10-19Clinical Trial Update: Leveraging EEG for Antidepressant Prediction With Sertraline and Escitalopram [Phase 4]
Phase 4 clinical trial investigating EEG-based prediction for antidepressant response to sertraline and escitalopram has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2020-03-20Clinical Trial Update: Treatment for Cognitive Impairment in Depression [Phase 3]
A Phase 3 clinical trial for cognitive impairment in major depressive disorder was withdrawn.
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CLINICAL_TRIALS withdrawal · 2020-02-11Clinical Trial Update: Single-dose Ketamine for the Reduction of Pain and Depression in the Emergency Department [Phase 2, Phase 3]
A clinical trial investigating single-dose ketamine for acute pain and depression in the emergency department was withdrawn.
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CLINICAL_TRIALS withdrawal · 2020-01-28Clinical Trial Update: Endogenous Opioid Modulation by Ketamine [Phase 3]
Phase 3 clinical trial on endogenous opioid modulation by ketamine for major depressive disorder has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2019-07-19Clinical Trial Update: Study of Rapastinel as Monotherapy in Major Depressive Disorder (MDD) [Phase 3]
Phase 3 study of rapastinel monotherapy for major depressive disorder has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2019-04-18Clinical Trial Update: A Comparison of Medication Augmentation and PST in the Treatment of Depression in Older Adults [Phase 4]
Phase 4 trial comparing medication augmentation versus PST for depression in older adults was withdrawn.
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CLINICAL_TRIALS withdrawal · 2019-02-07Clinical Trial Update: Effectiveness and Satisfaction With Brief Synchronous Tele-psychiatry Consult [NA]
A Mayo Clinic study evaluating the effectiveness and satisfaction of brief synchronous tele-psychiatry for depression has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2019-02-05Clinical Trial Update: Electronic-Measurement Based Care for Major Depressive Disorder [NA]
The clinical trial NCT01583998 on electronic-measurement based care for Major Depressive Disorder has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2018-07-03Clinical Trial Update: Health-eBrain Study [NA]
A clinical trial investigating depression and caregiver burden (Health-eBrain) has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2018-03-29Clinical Trial Update: fMRI-neuronavigated rTMS for the Treatment of Major Depression Associated With TBI [Phase 2]
A Phase 2 clinical trial investigating fMRI-neuronavigated repetitive transcranial magnetic stimulation for major depressive disorder associ…
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CLINICAL_TRIALS withdrawal · 2018-03-09Clinical Trial Update: Examining the Feasibility and Effectiveness of Case Manager Delivered Problem Solving Therapy on Late Life Depression [NA]
This clinical trial update notes that the study evaluating case manager-delivered problem-solving therapy for late-life depression has been …
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CLINICAL_TRIALS withdrawal · 2018-02-28Clinical Trial Update: Using the LENA System in Early Intervention [NA]
The UNC Chapel Hill–sponsored trial evaluating the LENA System in early intervention for depression has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2017-11-29Clinical Trial Update: The Antidepressant Efficacy of Low Frequency rTMS as add-on [NA]
The clinical trial evaluating low-frequency rTMS as an add-on treatment for depression has been withdrawn from clinicaltrials.gov.
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CLINICAL_TRIALS withdrawal · 2017-11-20Clinical Trial Update: Evaluating the Efficacy of Magnetic Seizure Therapy in Treatment Resistant Depression. [NA]
The clinical trial evaluating Magnetic Seizure Therapy for treatment-resistant depression has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2017-10-27Clinical Trial Update: Family Focused Nursing for Elderly Medical Patients [NA]
A clinical trial evaluating family-focused nursing for elderly medical patients with depression has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2017-08-17Clinical Trial Update: Mobile Phone App for Depression and Anxiety in Young Men Who Are Attracted to Men [Phase 1, Phase 2]
A Phase 1/2 clinical trial of a mobile phone app for depressive symptoms and generalized anxiety in young men who have sex with men was with…