Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS withdrawal · 2025-04-27Clinical Trial Update: A Study of Esketamine Nasal Spray Plus a New Standard-of-care Oral Antidepressant or Placebo Nasal Spray Plus a New Standard-of-care Oral Antidepressant in Adult and Elderly Participants With Treatment-resistant Depression [Phase 3]
A Phase 3 study of esketamine nasal spray plus a standard antidepressant for treatment-resistant depression has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2025-04-27Clinical Trial Update: New Mothers Alpha-Stim [NA]
A clinical trial (NCT04770181) evaluating New Mothers Alpha-Stim for anxiety, depression, insomnia, and sleep quality has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2025-04-16Clinical Trial Update: Humanoid Robot vs Treatment as Usual for Loneliness [NA]
A trial comparing a humanoid robot intervention to treatment as usual for loneliness and depression has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2025-02-28Clinical Trial Update: Intervention for Rural Cancer Patients [NA]
The clinical trial NCT05091593, evaluating an intervention for rural cancer patients with outcomes related to depression and quality of life…
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CLINICAL_TRIALS withdrawal · 2025-02-07Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of REL-1017 As Adjunctive Treatment of Major Depressive Disorder (MDD) [Phase 3]
A Phase 3 study evaluating REL-1017 as an adjunctive treatment for major depressive disorder has been withdrawn. The sponsor is MGGM LLC.
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CLINICAL_TRIALS withdrawal · 2025-02-06Clinical Trial Update: Clinical Investigation of Syndi [NA]
The clinical investigation of Syndi, sponsored by Newcastle University, has been withdrawn; the trial targeted depression and anxiety-relate…
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CLINICAL_TRIALS withdrawal · 2025-02-05Clinical Trial Update: Immediate Effects of DLPFC tDCS on Attention Bias [NA]
A Johns Hopkins University-sponsored trial evaluating the immediate effects of dorsolateral prefrontal cortex transcranial direct current st…
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CLINICAL_TRIALS withdrawal · 2025-02-03Clinical Trial Update: Pilot Study: Investigating Mood Changes After Slow-wave Enhancement [NA]
This clinical trial update notes that the pilot study on mood changes after slow-wave enhancement has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2024-12-04Clinical Trial Update: 30-Minutes of Listening to Calming Music on Attendees of a Workshop Session at a Local Conference [NA]
A University of Florida-sponsored trial evaluating 30 minutes of calming music for conference attendees with depression and anxiety has been…
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CLINICAL_TRIALS withdrawal · 2024-12-02Clinical Trial Update: Does rTMS Induce Synaptic Plasticity? [Phase 1]
Phase 1 trial investigating whether repetitive transcranial magnetic stimulation (rTMS) induces synaptic plasticity in Major Depressive Diso…
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CLINICAL_TRIALS withdrawal · 2024-09-23Clinical Trial Update: Quantifying tACS-driven Improvement of Working Memory in Depression [NA]
A clinical trial evaluating whether transcranial alternating current stimulation (tACS) improves working memory in people with major depress…
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CLINICAL_TRIALS withdrawal · 2024-09-19Clinical Trial Update: Lithium Versus Paroxetine in Major Depression [Phase 4]
A Phase 4 trial comparing lithium versus paroxetine for major depressive disorder has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2024-09-19Clinical Trial Update: Creatine Monohydrate Use for Preventing Altitude Induced Depression [Phase 4]
A Phase 4 clinical trial evaluating creatine monohydrate to prevent altitude-induced depression has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2024-08-23Clinical Trial Update: Program AACTIVE: African Americans Coming Together to Increase Vital Exercise [NA]
A clinical trial titled Program AACTIVE evaluating an exercise program for African Americans with Type 2 Diabetes and Depression has been wi…
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CLINICAL_TRIALS withdrawal · 2024-07-25Clinical Trial Update: Psilocybin for Major Depressive Disorder [Phase 2]
Phase 2 study evaluating psilocybin for Major Depressive Disorder has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2024-07-19Clinical Trial Update: PREGBRAIN - Magnetic Stimulation of the Brain in Depressed Pregnant Women [NA]
The PREGBRAIN trial assessing magnetic stimulation for depression in pregnant women has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2024-07-16Clinical Trial Update: Accelerated Intermittent Theta-Burst Stimulation for Opiate Use Disorder [NA]
The clinical trial NCT03804619 evaluating accelerated intermittent theta-burst stimulation for opioid use disorder has been withdrawn. The s…
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CLINICAL_TRIALS withdrawal · 2024-07-16Clinical Trial Update: aTBS for Treatment of Depression in AUD [NA]
A clinical trial investigating aTBS for treatment of depression in individuals with Alcohol Use Disorder was withdrawn.
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CLINICAL_TRIALS withdrawal · 2024-06-25Clinical Trial Update: Using EEG to Predict Depression Treatment Response to rTMS in Patients With Major Depression
A clinical trial evaluating EEG predictors of response to repetitive transcranial magnetic stimulation in major depressive disorder has been…
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CLINICAL_TRIALS withdrawal · 2024-06-11Clinical Trial Update: Creatine for Treatment of Depression Associated With Type 2 Diabetes [Phase 4]
A Phase 4 clinical trial evaluating creatine for depression in patients with type 2 diabetes has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2024-05-16Clinical Trial Update: Augmentation of Standard Psychotherapy With a Habit Change App [NA]
The trial evaluating augmentation of standard psychotherapy with a habit-change app has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2024-05-07Clinical Trial Update: Targeted Group-based Psychotherapy to Address Emotional Stress in at Risk ICU Survivors [NA]
A clinical trial studying targeted group-based psychotherapy for emotional stress in at-risk ICU survivors has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2024-05-03Clinical Trial Update: First-In-Human (FIH), Single Ascending Dose (SAD) Study of FluoroEthylNorMemantine (FENM) [Phase 1]
The first-in-human single ascending dose study of FluoroEthylNorMemantine (FENM) by ReST Therapeutics has been withdrawn; the listed conditi…
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CLINICAL_TRIALS withdrawal · 2024-01-05Clinical Trial Update: VA Aripiprazole vs Esketamine for Treatment Resistant Depression [Phase 4]
A Phase 4 trial comparing aripiprazole vs esketamine for treatment-resistant depression was withdrawn.
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CLINICAL_TRIALS withdrawal · 2023-11-14Clinical Trial Update: Anti-suicidal Effects of Buprenorphine In Depressed Individuals [Phase 3]
A Phase 3 trial evaluating buprenorphine for anti-suicidal effects in depressed individuals has been withdrawn.