Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2016-01-29Clinical Trial Update: Paliperidone and Lithium in the Treatment of Suicidality - Treatment Indication and Epigenetic Regulation [Phase 4]
Phase 4 clinical trial evaluating the combination of paliperidone and lithium for suicidality in adults with major depressive disorder. The …
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CLINICAL_TRIALS trial_result · 2016-01-29Clinical Trial Update: Development of an Insomnia Treatment for Depressed Adolescents [NA]
A clinical trial conducted by the University of Michigan to develop an insomnia treatment for adolescents with depression has completed.
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CLINICAL_TRIALS trial_result · 2016-01-28Clinical Trial Update: Serotonin Transporter Density in Late-life Depression With and Without Dementia [Phase 2]
This Phase 2 clinical trial update examines serotonin transporter density in older adults with depression, comparing those with and without …
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CLINICAL_TRIALS trial_result · 2016-01-28Clinical Trial Update: Neurorestorative Effects of Electroconvulsive Therapy (ECT) in Patients With Severe Late Life Depression [NA]
This completed clinical trial from KU Leuven evaluated the neurorestorative effects of electroconvulsive therapy in patients with severe lat…
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CLINICAL_TRIALS trial_result · 2016-01-28Clinical Trial Update: Antidepressants to Promote Recovery of Cardiac Patients Suffering From Depression [Phase 4]
Phase 4 trial evaluating antidepressants to promote recovery in patients with acute coronary syndrome and depression has been terminated.
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CLINICAL_TRIALS trial_result · 2016-01-22Clinical Trial Update: Life Goals Collaborative Care to Improve Health Outcomes in Mental Disorders [NA]
The Life Goals Collaborative Care trial evaluating health outcomes in mental disorders has completed, with results posted on Jan 22, 2016.
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CLINICAL_TRIALS trial_result · 2016-01-22Clinical Trial Update: Neuropsychobiological Correlates of Sex-steroid Hormone Manipulation in Healthy Women: a Risk Model for Depression [NA]
This entry notes the completion of a clinical trial investigating the neuropsychobiological correlates of sex-steroid hormone manipulation i…
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CLINICAL_TRIALS trial_result · 2016-01-21Clinical Trial Update: Magnesium Sulfate Versus 5% Dextrose With Treatment Resistant Depression [NA]
The trial comparing magnesium sulfate to 5% dextrose for treatment-resistant depression has completed; the summary does not include efficacy…
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CLINICAL_TRIALS trial_result · 2016-01-21Clinical Trial Update: Pain Processing in Anxiety and Depression
A completed clinical trial run by the Danish Pain Research Center examining how pain processing relates to anxiety and depression.
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CLINICAL_TRIALS trial_result · 2016-01-20Clinical Trial Update: Functional Neuroanatomy and Regional Metabolism Before and After Treatment With Duloxetine
This clinical trial update investigates functional neuroanatomy and regional metabolism in major depressive disorder before and after treatm…
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CLINICAL_TRIALS trial_result · 2016-01-20Clinical Trial Update: Transcranial Direct Current Stimulation as an Augmenting Intervention for Major Depression [Phase 2, Phase 3]
This entry summarizes a clinical trial update on using transcranial direct current stimulation as an augmenting therapy for Major depressive…
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CLINICAL_TRIALS trial_result · 2016-01-18Clinical Trial Update: Desvenlafaxine Succinate (Pristiq): Postmarketing Surveillance Study Among Filipino Patients
A postmarketing surveillance study of desvenlafaxine succinate (Pristiq) in Filipino patients with major depressive disorder and vasomotor s…
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CLINICAL_TRIALS trial_result · 2016-01-15Clinical Trial Update: Pharmacokinetics and Tolerability of Vortioxetine (Lu AA21004) in Child and Adolescent Patients With Depressive or Anxiety Disorder [Phase 2]
This Phase 2 study reports pharmacokinetics and tolerability of vortioxetine in children and adolescents with depressive or anxiety disorder…
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CLINICAL_TRIALS trial_result · 2016-01-15Clinical Trial Update: Pharmacotherapy in Depression With Panic Spectrum [Phase 4]
Phase 4 clinical trial update for pharmacotherapy in major depressive disorder with panic-spectrum; the study has completed. No specific dru…
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CLINICAL_TRIALS trial_result · 2016-01-15Clinical Trial Update: MOMCare: Culturally Relevant Treatment Services for Perinatal Depression [NA]
This completed clinical trial evaluated MOMCare, a culturally relevant treatment program for perinatal depression, sponsored by the Universi…
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CLINICAL_TRIALS trial_result · 2016-01-14Clinical Trial Update: Prediction of Quality of Life in Cardiovascular Disease
Completed clinical trial evaluating prediction of quality of life in patients with cardiovascular disease. The study encompassed conditions …
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CLINICAL_TRIALS trial_result · 2016-01-14Clinical Trial Update: Vigorous Exercise for Depressed Smokers [NA]
A Mayo Clinic-sponsored trial studied the effects of vigorous exercise on depression and nicotine dependence in smokers, and the study statu…
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CLINICAL_TRIALS trial_result · 2016-01-13Clinical Trial Update: Effectiveness of Interpersonal Psychotherapy (IPT) for Men and Women Prisoners With Major Depression [Phase 3]
Phase 3 trial assessing the effectiveness of interpersonal psychotherapy for major depressive disorder in male and female prisoners; study c…
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CLINICAL_TRIALS trial_result · 2016-01-13Clinical Trial Update: Group Interpersonal Psychotherapy for Treatment of Major Depressive Disorder Following Perinatal Loss [NA]
A completed clinical trial evaluated group interpersonal psychotherapy for treating major depressive disorder after perinatal loss (miscarri…
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CLINICAL_TRIALS trial_result · 2016-01-12Clinical Trial Update: Impact of Immune Challenge on Triple Network Connectivity in Humans [NA]
This clinical trial update reports on a study investigating how an immune challenge affects triple network connectivity in humans, with majo…
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CLINICAL_TRIALS trial_result · 2016-01-11Clinical Trial Update: Robust Evaluation to Measure Improvements in Nonadherence From Low-cost Devices [NA]
A completed clinical trial evaluated the effectiveness of low-cost devices in improving patient adherence across multiple conditions. The up…
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CLINICAL_TRIALS trial_result · 2016-01-11Clinical Trial Update: Health Promotion in Early Adolescence: Sleep, Activity, and Emotion Regulation [NA]
This completed clinical trial evaluated a health-promotion program in early adolescence focusing on sleep, physical activity, and emotion re…
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CLINICAL_TRIALS trial_result · 2016-01-08Clinical Trial Update: Efficacy and Safety Analyses of Mirtazapine in NSCLC Patients With Depression [Phase 2]
Phase 2 trial update analyzing the efficacy and safety of mirtazapine in patients with non-small cell lung cancer and depression.
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CLINICAL_TRIALS trial_result · 2016-01-07Clinical Trial Update: Study of Genes in Relation to Seasonal Affective Disorder and Major Depressive Disorder
A completed University of Pittsburgh study investigated genetic factors related to Seasonal Affective Disorder and Major Depressive Disorder…
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CLINICAL_TRIALS trial_result · 2016-01-01Clinical Trial Update: Study of the Safety and Efficacy of Two Fixed Doses of OPC-34712 as Adjunctive Therapy in the Treatment of Adults With Major Depressive Disorder (the Polaris Trial) [Phase 3]
Phase 3 study evaluating two fixed doses of OPC-34712 as adjunctive therapy for adults with major depressive disorder has completed. Results…