Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-01-16Clinical Trial Update: Reducing Suicide Risk in Older Veterans Using Problem Solving Therapy [NA]
This clinical trial evaluating problem solving therapy to reduce suicide risk in older veterans has been terminated.
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CLINICAL_TRIALS trial_result · 2026-01-16Clinical Trial Update: SOVA Ambassadors Community Setting [NA]
University of Pittsburgh sponsored a trial for major depressive disorder that was terminated, with results posted on 2026-01-16.
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CLINICAL_TRIALS trial_result · 2026-01-15Clinical Trial Update: Cross-sectoral Collaboration in Multidisciplinary Treatment of Trauma-affected Refugees [NA]
Completed clinical trial evaluating cross-sectoral, multidisciplinary treatment for trauma-affected refugees, with outcomes related to post-…
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CLINICAL_TRIALS trial_result · 2026-01-15Clinical Trial Update: Improving Adherence to Homework During Therapy [NA]
A completed University of South Florida trial evaluated strategies to improve adherence to homework during therapy for anxiety and depressio…
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CLINICAL_TRIALS trial_result · 2026-01-14Clinical Trial Update: Clinical Trials to Evaluate Metformin to Treat Depression in People Living With HIV [Phase 2]
A Phase 2 clinical trial is evaluating metformin as a treatment for depression in people living with HIV. The study is not yet recruiting.
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CLINICAL_TRIALS trial_result · 2026-01-14Clinical Trial Update: Role Of Non-Specific Effects in The Treatment of Depression With Esketamine [NA]
A Yale-led trial evaluating non-specific effects in the treatment of depressive episodes with esketamine was terminated; results were posted…
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CLINICAL_TRIALS trial_result · 2026-01-13Clinical Trial Update: Testing the Effectiveness of Cognitive Training Among Depressed Patients Receiving Esketamine Treatment [NA]
A clinical trial evaluating cognitive training for patients with major depressive disorder receiving esketamine has been suspended, per the …
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CLINICAL_TRIALS trial_result · 2026-01-13Clinical Trial Update: Mindfulness-based Cognitive Therapy for the Chronic Pain-depression Co-morbidity Among Older Black Adults in the Community; The Quiet Focus Open Pilot [NA]
This completed open-pilot trial evaluated mindfulness-based cognitive therapy for the co-occurrence of chronic pain and depression among old…
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CLINICAL_TRIALS trial_result · 2026-01-12Clinical Trial Update: Intervention Effect of High Definition Transcranial Direct Current Stimulation (HD-tDCS) on Depressive Disorder [NA]
A completed clinical trial examined the effect of high-definition transcranial direct current stimulation (HD-tDCS) on depressive disorder, …
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CLINICAL_TRIALS trial_result · 2026-01-12Clinical Trial Update: Effectiveness of Exercise, Walking, and Education on Mental Health, Mobility and Quality of Life in Elderly Residents of Nursing Homes [NA]
This completed clinical trial evaluated whether a program combining exercise, walking, and education improves mental health, mobility, and q…
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CLINICAL_TRIALS trial_result · 2026-01-12Clinical Trial Update: Transcranial Magnetic Stimulation for Youth With Treatment-Resistant Major Depressive Disorder [Phase 2]
Phase 2 trial of transcranial magnetic stimulation for youths with treatment-resistant major depressive disorder has been suspended.
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CLINICAL_TRIALS trial_result · 2026-01-12Clinical Trial Update: The Effect of Mindfulness-based Stress Reduction Programme Given to Infertile Women [NA]
A completed clinical trial evaluating a mindfulness-based stress reduction program for infertile women. The study examines effects on depres…
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CLINICAL_TRIALS trial_result · 2026-01-09Clinical Trial Update: Allogeneic Human Mesenchymal Stem Cell Infusion vs Placebo in Alcohol Use Disorder and Major Depression. [Phase 1, Phase 2]
A completed Phase 1/2 clinical trial comparing allogeneic mesenchymal stem cell infusion to placebo in adults with major depressive disorder…
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CLINICAL_TRIALS trial_result · 2026-01-09Clinical Trial Update: Effect of Family-Based Prevention on Children of Depressed Parents [Phase 1]
A Phase 1 clinical trial evaluated a family-based prevention program for children of depressed parents to assess safety and feasibility. The…
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CLINICAL_TRIALS trial_result · 2026-01-09Clinical Trial Update: Effects of a 10-Week Zumba Program on Anxiety and Depression in Adults [NA]
This clinical trial reports the outcomes of a 10-week Zumba program on anxiety and depression in adults.
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CLINICAL_TRIALS trial_result · 2026-01-08Clinical Trial Update: Peer-Supported E-Health Intervention for College Student Weight Management and Mental Health [NA]
A completed clinical trial evaluated a peer-supported e-health intervention for weight management and mental health among college students.
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CLINICAL_TRIALS trial_result · 2026-01-08Clinical Trial Update: Impact of Ketamine On Depressive Symptoms In Patients Undergoing Lumbo-peritoneal Shunt Insertion [Phase 4]
Phase 4 study evaluating ketamine for depressive symptoms in patients undergoing lumbo-peritoneal shunt insertion has completed.
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CLINICAL_TRIALS trial_result · 2026-01-08Clinical Trial Update: Problem-Solving Therapy for Cancer Caregivers in Outpatient Palliative Care [NA]
This entry reports the completion of a clinical trial evaluating problem-solving therapy for caregivers of cancer patients in outpatient pal…
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CLINICAL_TRIALS trial_result · 2026-01-07Clinical Trial Update: Efficacy and Safety Study of BHV-7000 Monotherapy in Major Depression [Phase 2]
Phase 2 trial evaluating BHV-7000 as monotherapy for Major depressive disorder has completed, with efficacy and safety results reported in t…
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CLINICAL_TRIALS trial_result · 2026-01-07Clinical Trial Update: Multiple Ascending Dose Study of NH102 in Healthy Subjects [Phase 1]
Phase 1 multiple ascending dose study of NH102 in healthy subjects has completed, with depression listed as the condition.
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CLINICAL_TRIALS trial_result · 2026-01-06Clinical Trial Update: Objective Vascular Biomarkers as Triage for Depression in Chronic Atrophic Gastritis
This clinical trial update indicates a not-yet-recruiting study by the China Academy of Chinese Medical Sciences investigating objective vas…
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CLINICAL_TRIALS trial_result · 2026-01-05Clinical Trial Update: Progressing TAAR-1, Dopamine, and Norepinephrine in Depression Using Solriamfetol [Phase 3]
This Phase 3 trial by Axsome Therapeutics evaluates solriamfetol for major depressive disorder, targeting TAAR-1, dopamine, and norepinephri…
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CLINICAL_TRIALS trial_result · 2026-01-02Clinical Trial Update: A Study of Aticaprant 10 Milligrams (mg) as Adjunctive Therapy in Adult Participants With MDD With Moderate-to-severe Anhedonia and Inadequate Response to Current Antidepressant Therapy [Phase 3]
Phase 3 study of Aticaprant 10 mg as adjunctive therapy for adults with major depressive disorder and anhedonia has completed, with results …
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CLINICAL_TRIALS trial_result · 2026-01-02Clinical Trial Update: The Relationship Between Power Sleep and Sleep Quality, Depression, and Stress Levels in University Students [NA]
This completed clinical trial evaluates the relationship between power sleep and sleep quality, depression, and stress among university stud…
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CLINICAL_TRIALS trial_result · 2025-12-31Clinical Trial Update: Can Rumination-Focused Cognitive Behavioral Therapy Reduce the Risk of Cardio-vascular Disease? [NA]
This completed clinical trial from the University of Louisville examines whether rumination-focused cognitive behavioral therapy can reduce …