Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2016-11-08Clinical Trial Update: Contingency Management of Psychostimulant Abuse in the Severely Mentally Ill [NA]
A completed clinical trial evaluating contingency management for stimulant use disorder in individuals with severe mental illness.
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CLINICAL_TRIALS trial_result · 2016-11-07Clinical Trial Update: Light Therapy for Bipolar Disorder. Efficacy of Light Therapy for Bipolar Depression: A Randomized Controlled Trial [Phase 3]
Phase 3 randomized controlled trial evaluating the efficacy of light therapy for bipolar depression. Results were posted in 2016.
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CLINICAL_TRIALS trial_result · 2016-11-07Clinical Trial Update: Safety and Efficacy of MK-6096 as Adjunctive Therapy in Participants With Major Depressive Disorder And Partial Response to Antidepressant Monotherapy (MK-6096-022) [Phase 2]
Phase 2 clinical trial update for MK-6096 as adjunctive therapy in participants with major depressive disorder and partial response to antid…
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CLINICAL_TRIALS trial_result · 2016-11-07Clinical Trial Update: Study of Medication and Placebo Response in Major Depression [Phase 4]
A Phase 4 study comparing a medication to placebo in major depressive disorder has completed.
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CLINICAL_TRIALS trial_result · 2016-11-02Clinical Trial Update: A Study of RO4917523 in Patients With Treatment Resistant Depression [Phase 2]
Phase 2 study of RO4917523 for treatment-resistant depression has completed.
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CLINICAL_TRIALS trial_result · 2016-11-02Clinical Trial Update: ARTDeCo Study: A Study of RO4995819 in Patients With Major Depressive Disorder And Inadequate Response to Ongoing Antidepressant Treatment [Phase 2]
The ARTDeCo Phase 2 study of RO4995819 in adults with major depressive disorder who have inadequate response to ongoing antidepressant treat…
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CLINICAL_TRIALS trial_result · 2016-11-02Clinical Trial Update: A Study of the Safety, Tolerability, and Pharmacokinetics of Multiple-Ascending Dose Basimglurant in Healthy Subjects and in Patients With Major Depressive Disorder (MDD) [Phase 1]
Phase 1 study evaluating the safety, tolerability, and pharmacokinetics of escalating doses of basimglurant in healthy volunteers and patien…
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CLINICAL_TRIALS trial_result · 2016-11-02Clinical Trial Update: MARIGOLD Study: A Study of RO4917523 Versus Placebo as Adjunctive Therapy in Patients With Major Depressive Disorder and an Inadequate Response to Ongoing Antidepressant Therapy [Phase 2]
MARIGOLD is a Phase 2 trial comparing RO4917523 to placebo as adjunctive therapy for major depressive disorder with inadequate response to o…
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CLINICAL_TRIALS trial_result · 2016-11-01Clinical Trial Update: Treating Depression With Physical Exercise [NA]
A completed clinical trial from Umeå University investigated physical exercise as a treatment for Depression.
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CLINICAL_TRIALS trial_result · 2016-11-01Clinical Trial Update: Repetitive Transcranial Magnetic Stimulation (rTMS) for Treatment Resistant Depressive Disorder [NA]
The clinical trial update reports that a repetitive transcranial magnetic stimulation (rTMS) study for treatment-resistant major depressive …
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CLINICAL_TRIALS trial_result · 2016-10-31Clinical Trial Update: Wake and Light Therapy to In-patients With Major Depression: Efficacy, Predictors and Patient Experiences [NA]
A completed clinical trial evaluating wake and light therapy for in-patients with major depressive disorder, assessing efficacy, predictors …
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CLINICAL_TRIALS trial_result · 2016-10-31Clinical Trial Update: Neural, Genetic, and Peripheral Correlates of SSRI Pharmaco-Response [Phase 4]
Phase 4 trial investigating neural, genetic, and peripheral biomarkers associated with SSRI response in depression; the study has completed.
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CLINICAL_TRIALS trial_result · 2016-10-28Clinical Trial Update: Study Of The Effects Of A New Antidepressant Therapy In Patients With Major Depressive Disorder (MDD) [Phase 2]
A Phase 2 clinical trial evaluating a new antidepressant for major depressive disorder has completed enrollment/status; sponsor is GlaxoSmit…
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CLINICAL_TRIALS trial_result · 2016-10-28Clinical Trial Update: Task Sharing Counseling Intervention by Community Health Workers for Prenatal Depression in South Africa [NA]
Completed clinical trial evaluating task-sharing counseling by community health workers for prenatal depression in South Africa.
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CLINICAL_TRIALS trial_result · 2016-10-27Clinical Trial Update: Heart Failure Caregiver Study [NA]
UCLA's Heart Failure Caregiver Study (NCT01937936) has completed. The study examined caregiver stress and depression in the context of heart…
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CLINICAL_TRIALS trial_result · 2016-10-26Clinical Trial Update: Mental Health E-screening in Pregnant and Postpartum Women [NA]
This Clinical Trial Update reports the completed status of a study evaluating mental health e-screening for depression and anxiety in pregna…
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CLINICAL_TRIALS trial_result · 2016-10-25Clinical Trial Update: Dose-Ranging Trial of Creatine Augmentation for Adolescent Females With Treatment-Resistant Major Depressive Disorder [EARLY_Phase 1]
A dose-ranging Phase 1 trial evaluating creatine augmentation for adolescent females with treatment-resistant major depressive disorder has …
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CLINICAL_TRIALS trial_result · 2016-10-24Clinical Trial Update: Lexapro for the Treatment of Traumatic Brain Injury (TBI) Depression & Other Psychiatric Conditions [Phase 2]
Phase 2 trial of escitalopram (Lexapro) for traumatic brain injury–related depression and other psychiatric conditions completed; results we…
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CLINICAL_TRIALS trial_result · 2016-10-24Clinical Trial Update: Cardiovascular Biomarkers and Quetiapine in Depression and Anxiety Patients [Phase 4]
A Phase 4 study evaluated cardiovascular biomarkers in patients with depression and anxiety treated with quetiapine; results have been poste…
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CLINICAL_TRIALS trial_result · 2016-10-21Clinical Trial Update: Hyperventilation Combined With Etomidate or Ketamine Anesthesia in ECT Treatment of Major Depression [Phase 4]
A Phase 4 clinical trial update evaluating hyperventilation with etomidate or ketamine anesthesia during electroconvulsive therapy for major…
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CLINICAL_TRIALS trial_result · 2016-10-20Clinical Trial Update: Effects of Cerebral Hypoperfusion and Its Reversal on Late-Life Depression [Phase 4]
A Phase 4 clinical trial investigating the effect of cerebral hypoperfusion and its reversal on late-life depression was terminated, with re…
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CLINICAL_TRIALS trial_result · 2016-10-19Clinical Trial Update: Trial of Collaborative Depression Care Management for HIV Patients [NA]
A completed clinical trial evaluating collaborative depression care management for patients with HIV; results were posted in October 2016.
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CLINICAL_TRIALS trial_result · 2016-10-18Clinical Trial Update: Cognitive Behavioral Therapy, Guided Self Help Versus Individual Therapy [Phase 3]
This update reports the completion of a Phase 3 trial comparing guided self-help cognitive behavioral therapy with standard individual thera…
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CLINICAL_TRIALS trial_result · 2016-10-17Clinical Trial Update: Study of Brain Response to Emotional Pictures Using a Magnetic Resonance Imaging (fMRI) While on Escitalopram [Phase 4]
Phase 4 clinical trial evaluating brain response to emotional pictures with fMRI in patients with major depressive disorder while on escital…
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CLINICAL_TRIALS trial_result · 2016-10-17Clinical Trial Update: Early Improvement in Individual Symptoms and Response to Antidepressants in Patients With Major Depressive Disorder
A clinical trial update reports early improvement in individual depressive symptoms and overall response to antidepressants in patients with…