Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-07-13Clinical Trial Update: GSK372475 PK Study in Healthy Volunteers [Phase 1]
Phase 1 pharmacokinetic study of GSK372475 in healthy volunteers has been completed, providing PK data for potential depressive disorder tre…
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CLINICAL_TRIALS trial_result · 2017-07-11Clinical Trial Update: Venlafaxine to Reduce Cocaine Dependence in Depressed Individuals [Phase 2]
Phase 2 clinical trial evaluated venlafaxine for reducing cocaine dependence in individuals with depression. The study status is completed.
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CLINICAL_TRIALS trial_result · 2017-07-07Clinical Trial Update: Developing New Clinical Management Strategies [Phase 4]
Phase 4 clinical trial update on new clinical management strategies for major depressive disorder; study completed with results posted in 20…
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CLINICAL_TRIALS trial_result · 2017-07-07Clinical Trial Update: Smoking Cessation for Depression and Anxiety Treatment [Phase 1]
A Phase 1 trial evaluating a smoking cessation treatment in adults with anxiety disorders and major depressive disorder has completed.
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CLINICAL_TRIALS trial_result · 2017-07-06Clinical Trial Update: CBT Depression Intervention for Co-Occurring Chronic Headache [NA]
The clinical trial update notes completion of a study evaluating a cognitive-behavioral therapy intervention for individuals with co-occurri…
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CLINICAL_TRIALS trial_result · 2017-07-05Clinical Trial Update: Creatine Augmentation Treatment in Major Depressive Disorder Subjects [NA]
A status update on a completed clinical trial evaluating creatine augmentation as a treatment for Major Depressive Disorder.
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: PET Whole Body Distribution Studies Using [11C]CUMI
A completed PET imaging study evaluated the whole-body distribution of the radioligand [11C]CUMI. The study involved individuals with depres…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Brain Imaging in Depression
A brain imaging clinical trial sponsored by the National Institute of Mental Health has completed, studying participants with depression and…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Serotonin Function During Depression
This completed NIH-sponsored trial examined serotonin function in individuals with depression (including involutional depression) and in hea…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Dopamine Receptor Imaging in Mood Disorders
The NIMH-sponsored clinical trial evaluating dopamine receptor imaging in mood disorders has completed, with conditions including major depr…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Brain Chemical Receptor Effects in Patients With Panic Disorder and Post-Traumatic Stress Disorder
This clinical trial update reports on brain chemical receptor effects in patients with Panic Disorder and Posttraumatic Stress Disorder. Maj…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Bone Mineral Density in Women With Major Depression
Completed clinical trial evaluating bone mineral density in women with major depressive disorder, with relevance to osteoporosis risk.
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Brain Regulation of Emotions in People With Depression and Anhedonia
This completed clinical trial from the National Institute of Mental Health investigates brain regulation of emotions in adults with major de…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Bone Loss in Premenopausal Women With Depression [Phase 4]
Phase 4 clinical trial update from NIMH reporting completion of a study on bone loss in premenopausal women with depression, examining osteo…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Evaluating Brain Responses to Facial Expressions in Major Depressive Disorder
Clinical trial update on brain responses to facial expressions in individuals with current or remitted major depressive disorder and healthy…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Function of Catecholamines in the Brain During Depression
This completed clinical trial from the National Institute of Mental Health investigated the role of catecholamines in brain function during …
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Neurocardiac Control in Major Depression
The National Institute of Mental Health-sponsored trial on neurocardiac control in major depressive disorder has completed.
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CLINICAL_TRIALS trial_result · 2017-06-26Clinical Trial Update: Evaluation of the Safety of Adjunct Brexpiprazole in Elderly Patients With Major Depressive Disorder and an Inadequate Response to Antidepressant Treatment [Phase 3]
Phase 3 trial update evaluating the safety of adjunct brexpiprazole in elderly patients with major depressive disorder who had an inadequate…
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CLINICAL_TRIALS trial_result · 2017-06-26Clinical Trial Update: Evaluation of a Mental Health Physician Support Program in Nova Scotia [NA]
Completed clinical trial evaluating a Mental Health Physician Support Program in Nova Scotia; results posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-06-22Clinical Trial Update: Depression, Adversity, and Stress Hormones (DASH) Study [NA]
The DASH study on depression, adversity, and stress hormones has completed. The update notes completion of the trial, with no efficacy resul…
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CLINICAL_TRIALS trial_result · 2017-06-21Clinical Trial Update: Dexamethasone and Ketamine on Change of Postoperative Mood [Phase 4]
Phase 4 clinical trial evaluating the combined effects of dexamethasone and ketamine on postoperative mood in patients with depressive sympt…
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CLINICAL_TRIALS trial_result · 2017-06-20Clinical Trial Update: Impact of an Eight Week Exercise Intervention in Treating Major Depressive Disorder [NA]
An eight-week exercise intervention is being studied for Major Depressive Disorder in a clinical trial, with the status currently UNKNOWN.
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CLINICAL_TRIALS trial_result · 2017-06-16Clinical Trial Update: A Randomized Controlled Trial of In-Home Tele-Behavioral Health Care Utilizing Behavioral Activation for Depression [NA]
This ClinicalTrials.gov entry reports the completion of a randomized controlled trial evaluating in-home tele-behavioral health care using B…
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CLINICAL_TRIALS trial_result · 2017-06-16Clinical Trial Update: Shared Decision-Making for Elderly Depressed Primary Care Patients [NA]
A completed clinical trial evaluated shared decision-making for elderly depressed patients in primary care. Results were posted on 2017-06-1…
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CLINICAL_TRIALS trial_result · 2017-06-12Clinical Trial Update: Omega 3 for Treatment of Depression in Patients With Heart Failure [Phase 3]
Phase 3 trial results for omega-3 fatty acids in treating depression among patients with heart failure have been posted.