Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-02-13Clinical Trial Update: Rapid Antidepressant Improvement Secondary to Excitatory Brain Responses [Phase 4]
A Phase 4 clinical trial examining rapid antidepressant improvements linked to excitatory brain responses in major depressive disorder has c…
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CLINICAL_TRIALS trial_result · 2026-02-13Clinical Trial Update: Specialized Pro-resolving Lipid Mediators and Treatment Resistant Depression [Phase 2]
A Phase 2 clinical trial evaluating specialized pro-resolving lipid mediators for treatment-resistant depression is active but not recruitin…
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CLINICAL_TRIALS trial_result · 2026-02-13Clinical Trial Update: Individualized Neuromodulation for Anhedonic Depression [NA]
A clinical trial evaluating individualized neuromodulation for anhedonic depression has completed.
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CLINICAL_TRIALS trial_result · 2026-02-13Clinical Trial Update: Enhanced Spatial Targeting in ECT Utilizing FEAST [NA]
A clinical trial update indicates that the University of Minnesota's study on Enhanced Spatial Targeting in ECT utilizing FEAST for treatmen…
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CLINICAL_TRIALS trial_result · 2026-02-13Clinical Trial Update: Frequency and E-field Enhancement of ITBS for Depression (FREED) [NA]
A clinical trial (FREED) evaluating frequency and electric-field enhancement of intermittent theta-burst stimulation for major depressive di…
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CLINICAL_TRIALS trial_result · 2026-02-12Clinical Trial Update: ACTing Minds: An ACT-based Videogame for Mental Health [NA]
Swansea University reports a completed trial of ACTing Minds, an ACT-based videogame for mental health, assessing its impact on depression a…
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CLINICAL_TRIALS trial_result · 2026-02-11Clinical Trial Update: Concurrent fMRI-guided rTMS and Cognitive Therapy for the Treatment of Major Depressive Episodes [NA]
A completed clinical trial examining concurrent fMRI-guided rTMS and cognitive therapy for major depressive disorder.
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CLINICAL_TRIALS trial_result · 2026-02-10Clinical Trial Update: Evaluating the Effectiveness of a School-based Stepped Care Treatment Model for Adolescent Depression in Pakistan [NA]
The trial update reports completion of an evaluation of a school-based stepped care treatment model for adolescent depression in Pakistan.
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CLINICAL_TRIALS trial_result · 2026-02-10Clinical Trial Update: Predicting SSRI Efficacy in Veterans With PTSD [Phase 4]
Phase 4 clinical trial evaluating whether SSRIs predict efficacy in veterans with PTSD (with major depressive disorder) has been terminated.
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CLINICAL_TRIALS trial_result · 2026-02-10Clinical Trial Update: My Coach Connect: An Automated Telephone-based Reporting System for Patients With Mental Illness [NA]
This trial update notes the completion of the study evaluating My Coach Connect, an automated telephone-based reporting system for patients …
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CLINICAL_TRIALS trial_result · 2026-02-09Clinical Trial Update: Feasibility Pilot of Accelerated Stimulation With TMS for Treatment of Major Depressive Disorder (FAST-MDD) [EARLY_Phase 1]
This is an early-phase (Phase 1) feasibility pilot that completed evaluation of accelerated stimulation with transcranial magnetic stimulati…
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CLINICAL_TRIALS trial_result · 2026-02-09Clinical Trial Update: Digital Mental Health Service for Non-Treatment Seeking Young Adults [NA]
A completed clinical trial from Northwestern University evaluating a digital mental health service for young adults not seeking treatment; r…
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CLINICAL_TRIALS trial_result · 2026-02-09Clinical Trial Update: Effect of Awareness-Based Stress Reducatıon Program Applıed to Parents Wıth A Chıld Wıth Autısm [NA]
A completed clinical trial evaluating an awareness-based stress reduction program for parents of children with autism. The study targeted mo…
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CLINICAL_TRIALS trial_result · 2026-02-06Clinical Trial Update: Pharmacogenomic-Guided Antidepressant Drug Prescribing in Cancer Patients [NA]
A clinical trial update describing pharmacogenomic-guided antidepressant prescribing for cancer patients. The study status is completed.
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CLINICAL_TRIALS trial_result · 2026-02-05Clinical Trial Update: The Effect of Laughter Therapy on Hemodialysis Patients [NA]
A completed clinical trial investigated laughter therapy for managing depression, anxiety, and quality of life in patients undergoing hemodi…
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CLINICAL_TRIALS trial_result · 2026-02-05Clinical Trial Update: A Behavioral Activation Prenatal and Postpartum Intervention for Depressed Pregnant Smokers [NA]
Update on a clinical trial evaluating a behavioral activation intervention for pregnant and postpartum individuals who are depressed and smo…
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CLINICAL_TRIALS trial_result · 2026-02-05Clinical Trial Update: A Group Therapy Based on the Bio-psycho-social Treatment Approach for Women With Chronic Pelvic and Chronic Belly Pain
This entry reports the termination of a clinical trial evaluating a group therapy based on a bio-psycho-social approach for women with chron…
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CLINICAL_TRIALS trial_result · 2026-02-04Clinical Trial Update: The Effect of IPS-MA- A Modified Early Supported Employment Intervention for Individuals With Mood or Anxiety Disorders [NA]
A completed clinical trial evaluated IPS-MA, a Modified Early Supported Employment program, for individuals with mood and anxiety disorders.
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CLINICAL_TRIALS trial_result · 2026-02-04Clinical Trial Update: Mental Health App for Cancer Survivors Study [NA]
A clinical trial evaluating a mental health app for head and neck cancer survivors with depression was terminated, according to the Universi…
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CLINICAL_TRIALS trial_result · 2026-02-04Clinical Trial Update: Integrated Mental Health Care and Vocational Rehabilitation to People With to Common Mental Disorders [NA]
A completed clinical trial evaluating integrated mental health care combined with vocational rehabilitation for people with common mental di…
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CLINICAL_TRIALS trial_result · 2026-02-04Clinical Trial Update: Integrated Mental Health Care and Vocational Rehabilitation to Individuals on Sick Leave Due to Anxiety and Depression [NA]
Completed clinical trial assessing integrated mental health care and vocational rehabilitation for individuals on sick leave due to anxiety …
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CLINICAL_TRIALS trial_result · 2026-02-03Clinical Trial Update: Study on the Antidepressant Effects and Mechanism of Action of Cang-ai Volatile Oil Based on Near-Infrared Functional Brain Imaging and the NT-Trk Signalling Pathway [NA]
This completed clinical trial evaluated the antidepressant effects and mechanism of action of Cang-ai volatile oil for depression. The study…
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CLINICAL_TRIALS trial_result · 2026-01-30Clinical Trial Update: Internet-Based Group CBT for Anxiety and Depression Among International Students [NA]
An update on a clinical trial testing internet-based group cognitive-behavioral therapy for anxiety and depression in international students…
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CLINICAL_TRIALS trial_result · 2026-01-29Clinical Trial Update: MOSAIC (MOthers' AdvocateS In the Community) for Pregnant Women and Mothers of Children Under 5 With Experience of Intimate Partner Violence (MOSAIC Plus) Open Trial [NA]
Completed open trial (MOSAIC Plus) evaluating an intervention for pregnant women and mothers with exposure to intimate partner violence and …
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CLINICAL_TRIALS trial_result · 2026-01-28Clinical Trial Update: Depression Prevention in Older Spousally-bereaved Adults [NA]
A completed clinical trial assessing depression prevention in older adults who recently experienced spousal bereavement; results have been p…