Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-03-09Clinical Trial Update: The Effect of Mobile Application-Based Education Given to Patients With Tracheostomy on Depression, Social Adaptation and Quality of Recovery [NA]
This completed clinical trial assessed the effect of mobile app-based education for patients with tracheostomies on depression, social adapt…
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CLINICAL_TRIALS trial_result · 2026-03-06Clinical Trial Update: Transcranial Direct Current Stimulation (tDCS) in Different Psychiatric Disorders [NA]
This update notes the completion of a study evaluating transcranial direct current stimulation (tDCS) across multiple psychiatric disorders.…
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CLINICAL_TRIALS trial_result · 2026-03-06Clinical Trial Update: The Relationship of Occupational Competence and Activity Role Participation to Life Satisfaction and Depression Severity in Women Exposed to Domestic Physical Violence at a Social Service Institution
A completed clinical trial evaluated how occupational competence and participation in daily activities relate to life satisfaction and depre…
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CLINICAL_TRIALS trial_result · 2026-03-04Clinical Trial Update: Probing the Dorsolateral Prefrontal Cortex and Central Executive Network for Improving Neuromodulation in Depression [NA]
Clinical trial update from Stanford University evaluating stimulation targeting the dorsolateral prefrontal cortex and central executive net…
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CLINICAL_TRIALS trial_result · 2026-03-03Clinical Trial Update: Teen Brain Training (TBT) [Phase 1]
A Phase 1 trial of Teen Brain Training (TBT) in adolescents has completed, with results posted. The study examined suicidality (suicidal ide…
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CLINICAL_TRIALS trial_result · 2026-03-03Clinical Trial Update: Prevention of Anhedonia in Children [NA]
The document reports the completed status of a clinical trial focused on preventing anhedonia in children, related to depression.
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CLINICAL_TRIALS trial_result · 2026-02-27Clinical Trial Update: The Efficacy and Safty of FMT in Patients With CID [Phase 1, Phase 2]
A Phase 1/2 clinical trial update assessing the efficacy and safety of fecal microbiota transplantation for chronic insomnia disorder, with …
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CLINICAL_TRIALS trial_result · 2026-02-27Clinical Trial Update: Adolescent Depression Screening and Treatment in Mozambican Primary Care [NA]
This entry reports the completion of a clinical trial evaluating adolescent depression screening and treatment in Mozambican primary care, w…
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CLINICAL_TRIALS trial_result · 2026-02-27Clinical Trial Update: CBTpro: Scaling up CBT for Psychosis Using Simulated Patients and Spoken Language Technologies [NA]
The CBTpro trial, scaling up CBT for psychosis using simulated patients and spoken language technologies, has completed and posted results. …
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CLINICAL_TRIALS trial_result · 2026-02-27Clinical Trial Update: Evaluation of Efficacy and Safety of Milsaperidone as Adjunctive Therapy in Patients With Major Depressive Disorder [Phase 3]
Phase 3 clinical trial evaluating the efficacy and safety of Milsaperidone as adjunctive therapy for Major Depressive Disorder; currently re…
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CLINICAL_TRIALS trial_result · 2026-02-27Clinical Trial Update: Esketamine for Prevention of Depression After Cytoreductive Surgery in Ovarian Cancer [NA]
This completed clinical trial assesses esketamine for prevention of depressive symptoms after cytoreductive surgery in patients with ovarian…
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CLINICAL_TRIALS trial_result · 2026-02-27Clinical Trial Update: Pain, Reward, Attention and Neurocircuitry: Biomarkers of Suicidality
A completed clinical trial examining biomarkers of suicidality in patients with major depressive disorder, focusing on pain, reward, attenti…
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CLINICAL_TRIALS trial_result · 2026-02-27Clinical Trial Update: A Brain Imaging Study to Assess the Binding of MSP-2020 to Serotonin 5-HT2A Receptors in Healthy Male Adults [Phase 1]
Phase 1 brain imaging study to evaluate MSP-2020 binding to serotonin 5-HT2A receptors in healthy male adults; the trial relates to incomple…
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CLINICAL_TRIALS trial_result · 2026-02-25Clinical Trial Update: Determine the Bioavailability of Selegiline TDS 6mg/24 Hours vs EMSAM in Healthy Subjects
A Phase 1 bioavailability study comparing Selegiline Transdermal System 6 mg/24 hours with EMSAM in healthy subjects has completed.
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CLINICAL_TRIALS trial_result · 2026-02-25Clinical Trial Update: Treatment of Psoriasis With Depression and/or Anxiety With Methotrexate vs Combined Methotrexate and Antidepressant [Phase 4]
Phase 4 trial comparing methotrexate alone versus methotrexate plus an antidepressant for patients with psoriasis and comorbid depression or…
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CLINICAL_TRIALS trial_result · 2026-02-25Clinical Trial Update: ROOM-LIGHT: Effect of a Dynamic Lighting System in Depressed Inpatients [NA]
The ROOM-LIGHT trial evaluated a dynamic lighting system for inpatients with major depressive disorder. The study has completed.
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CLINICAL_TRIALS trial_result · 2026-02-25Clinical Trial Update: ROOM-LIGHT: Dynamic LED-light as Treatment for Depressed Patients in Inpatient Wards [NA]
The ROOM-LIGHT trial evaluated dynamic LED-light therapy as a treatment for depressed inpatients; the study has completed.
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CLINICAL_TRIALS trial_result · 2026-02-25Clinical Trial Update: Electronic Self-monitoring on Regulation of the Sleep-wake Cycle to Reduce Relapse of Depression After Discharge [NA]
The clinical trial evaluating electronic self-monitoring of the sleep-wake cycle to reduce relapse of depression after discharge has complet…
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CLINICAL_TRIALS trial_result · 2026-02-24Clinical Trial Update: ENHANCE-EvideNce Led Co-created HeAlth Systems interventioNs for MLTCs CarE [NA]
This ClinicalTrials.gov entry indicates that the ENHANCE-EvideNce Led Co-created Health Systems interventions for MLTCs Care trial conducted…
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CLINICAL_TRIALS trial_result · 2026-02-20Clinical Trial Update: Virtual Reality-Enhanced Behavioral Activation for Older Adults With Depression [NA]
Stanford University is recruiting for a clinical trial evaluating virtual reality-enhanced behavioral activation to treat major depressive d…
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CLINICAL_TRIALS trial_result · 2026-02-18Clinical Trial Update: A Trial of the Safety and Efficacy of SEP-363856 in the Treatment of Adults With Major Depressive Disorder [Phase 2]
This document reports the completion of a Phase 2 trial evaluating the safety and efficacy of SEP-363856 in adults with major depressive dis…
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CLINICAL_TRIALS trial_result · 2026-02-18Clinical Trial Update: Preventing Psychological Distress and Suicidal Behaviours: a Web-based and Mobile Suicide Prevention Intervention in the General Population [NA]
The document reports the completion of a web-based and mobile suicide prevention intervention tested in the general population. It lists the…
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CLINICAL_TRIALS trial_result · 2026-02-17Clinical Trial Update: Effectiveness and Implementation of eScreening in Post 9/11 Transition Programs [NA]
This clinical trial update reports on the effectiveness and implementation of electronic screening (eScreening) in VA Post-9/11 transition p…
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CLINICAL_TRIALS trial_result · 2026-02-17Clinical Trial Update: Feasibility and Acceptability of an Online ACT Intervention for Disorders of Gut-Brain Interaction - Beta Trial [NA]
This completed beta trial assessed the feasibility and acceptability of an online Acceptance and Commitment Therapy (ACT) intervention for d…
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CLINICAL_TRIALS trial_result · 2026-02-17Clinical Trial Update: A Study of Aticaprant 10 mg as Adjunctive Therapy in Adult Participants With Major Depressive Disorder (MDD) With Moderate-to-severe Anhedonia and Inadequate Response to Current Antidepressant Therapy and Long-term Extension Treatment With Aticaprant [Phase 3]
A Phase 3 trial evaluating aticaprant 10 mg as adjunctive therapy for adults with major depressive disorder and moderate-to-severe anhedonia…