Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2021-04-28Clinical Trial Update: Thinking Healthy Program Peer Delivered Plus [NA]
Completed clinical trial assessing Thinking Healthy Program Peer Delivered Plus for depression; results posted in 2021.
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CLINICAL_TRIALS trial_result · 2021-04-20Clinical Trial Update: Vortioxetine in Patients With Depression Coexisting With General Anxiety Disorder (GAD) [Phase 4]
Phase 4 trial update evaluating vortioxetine in patients with major depressive disorder coexisting with generalized anxiety disorder has bee…
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CLINICAL_TRIALS trial_result · 2021-04-08Clinical Trial Update: Nitrous Oxide for Major Depressive Disorder [Phase 2]
Phase 2 clinical trial update for nitrous oxide targeting major depressive disorder has completed.
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CLINICAL_TRIALS trial_result · 2021-04-01Clinical Trial Update: Telehealth Cognitive Behavioral Therapy for Depression in Parkinson's Disease (PD) [NA]
A completed clinical trial evaluating telehealth-based cognitive behavioral therapy for depression in Parkinson's disease with results poste…
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CLINICAL_TRIALS trial_result · 2021-04-01Clinical Trial Update: Study of a Transdiagnostic, Emotion-focused Group Intervention for Young Adults With Substance Use Disorders [NA]
A completed clinical trial assessing a transdiagnostic, emotion-focused group intervention for young adults with substance use disorders, wi…
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CLINICAL_TRIALS trial_result · 2021-03-26Clinical Trial Update: Vortioxetine in the Treatment of Depression Associated With Head and Neck Cancers Undergoing Radiotherapy [Phase 3]
Phase 3 trial evaluating vortioxetine for depression associated with radiation injuries in patients with head and neck cancer undergoing rad…
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CLINICAL_TRIALS trial_result · 2021-03-24Clinical Trial Update: A Study to Assess the Efficacy and Safety of AXS-05 in Subjects With Treatment Resistant Major Depressive Disorder [Phase 3]
Phase 3 trial assessing efficacy and safety of AXS-05 in treatment-resistant major depressive disorder has completed.
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CLINICAL_TRIALS trial_result · 2021-03-23Clinical Trial Update: Neural Changes Associated With a Mindfulness-based Intervention for Young Adults With Childhood Maltreatment [NA]
Completed clinical trial evaluating neural changes associated with a mindfulness-based intervention in young adults with a history of childh…
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CLINICAL_TRIALS trial_result · 2021-03-18Clinical Trial Update: Wake Therapy in the Treatment of Depression [NA]
Clinical trial update for wake therapy in depression completed; results posted in 2021.
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CLINICAL_TRIALS trial_result · 2021-03-17Clinical Trial Update: Safety, Tolerability, PK Profile, and Symptom Response of a 7-Day Dosing With 25 mg or 50 mg Daily of REL-1017 in MDD [Phase 2]
Phase 2 trial update for REL-1017 in major depressive disorder shows safety, tolerability, pharmacokinetics, and symptom response with 7-day…
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CLINICAL_TRIALS trial_result · 2021-03-17Clinical Trial Update: Cognitive Behavioural Therapy Software for the Treatment of Depression in People With Multiple Sclerosis [NA]
A completed clinical trial evaluating cognitive behavioural therapy software for treating depression in people with multiple sclerosis; resu…
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CLINICAL_TRIALS trial_result · 2021-03-15Clinical Trial Update: A Study of ALKS 5461 for Treatment Refractory Major Depressive Disorder (MDD) [Phase 3]
Phase 3 trial update for ALKS 5461 in treatment-refractory major depressive disorder completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-03-10Clinical Trial Update: Meru Health Ascend Mobile Intervention for Depression in Middle Aged and Older Adults [Phase 2, Phase 3]
A clinical trial update for Meru Health Ascend mobile intervention targeting depression in middle-aged and older adults, completed phases 2 …
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CLINICAL_TRIALS trial_result · 2021-02-23Clinical Trial Update: The Antidepressive Effect of rTMS as add-on to ECT [NA]
A terminated clinical trial investigating the antidepressive effect of rTMS as an add-on to ECT in depression.
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CLINICAL_TRIALS trial_result · 2021-02-16Clinical Trial Update: The Influence of Probiotic Supplementation on Depressive Symptoms, Inflammation and Oxidative Stress Parameters and Faecal Microbiota in Patients With Depression Depending on Metabolic Syndrome Comorbidity [Phase 3]
Phase 3 clinical trial investigating the effects of probiotic supplementation on depressive symptoms, inflammation, oxidative stress, and gu…
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CLINICAL_TRIALS trial_result · 2021-02-12Clinical Trial Update: Title: Evaluation of a Novel PET Radioligand for Phosphodiesterase-4D (PDE4D) [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating a novel PET radioligand targeting PDE4D for depression; study completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-02-09Clinical Trial Update: Metformin, Vitamin D, and Depression in Polycystic Ovary Syndrome (PCOS) Trial [Phase 4]
Phase 4 trial investigating metformin, vitamin D, and depression in polycystic ovary syndrome was terminated; results posted previously.
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CLINICAL_TRIALS trial_result · 2021-02-09Clinical Trial Update: Korean Post Marketing Surveillance to Observe Effectiveness and Safety of PRISTIQ
Post-marketing surveillance study assessing effectiveness and safety of Pristiq (desvenlafaxine) in major depressive disorder completed with…
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CLINICAL_TRIALS trial_result · 2021-02-04Clinical Trial Update: Focal Electrically-Administered Seizure Therapy (FEAST) Studies at Two Enrolling Sites to Further Test and Refine the Treatment [Phase 2, Phase 3]
Phase 2/3 FEAST trial updates completed at two sites evaluating Focal Electrically-Administered Seizure Therapy for depression.
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CLINICAL_TRIALS trial_result · 2021-01-29Clinical Trial Update: Lithium Versus Paroxetine in Patients With Major Depression Who Have a Family History of Bipolar Disorder or Suicide [Phase 3]
A Phase 3 trial comparing lithium to paroxetine in patients with major depressive disorder and a family history of bipolar disorder or suici…
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CLINICAL_TRIALS trial_result · 2021-01-28Clinical Trial Update: A Comparison of Sertraline-reboxetine Combination Therapy Versus Sertraline or Reboxetine Monotherapy in the Treatment of Major Depression. [Phase 2]
Phase 2 trial comparing sertraline-reboxetine combination to sertraline or reboxetine monotherapy for major depressive disorder has complete…
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CLINICAL_TRIALS trial_result · 2021-01-27Clinical Trial Update: A Comparison of Sertraline Versus Venlafaxine XR in the Treatment of Major Depression [Phase 4]
Phase 4 trial comparing sertraline to venlafaxine XR in adults with major depressive disorder has completed.
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CLINICAL_TRIALS trial_result · 2021-01-26Clinical Trial Update: Quality of Life and Self-esteem After Botox® Injections in Depressed and Non-depressed Patients [Phase 4]
Phase 4 clinical trial evaluating quality of life and self-esteem after Botox injections in depressed and non-depressed patients.
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CLINICAL_TRIALS trial_result · 2021-01-13Clinical Trial Update: Antidepressant Response in the Treatment of Depressive Symptoms and Frailty Characteristics in Older Adults [Phase 4]
A Phase 4 clinical trial assessing antidepressant response for depressive symptoms and frailty in older adults has been completed with resul…
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CLINICAL_TRIALS trial_result · 2021-01-07Clinical Trial Update: Psilocybin-assisted Group Therapy for Demoralization in Long-term AIDS Survivors [Phase 1]
Phase 1 clinical trial evaluating psilocybin-assisted group therapy for demoralization in long-term AIDS survivors; completed with results p…