Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2022-02-14Clinical Trial Update: Comparison of Vortioxetine and Desvenlafaxine in Adult Patients Suffering From Depression [Phase 4]
Phase 4 trial comparing vortioxetine and desvenlafaxine in adults with Major Depressive Disorder has completed.
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CLINICAL_TRIALS trial_result · 2022-02-10Clinical Trial Update: COVID-19 and the Healthy Minds Program for Educators [NA]
A completed clinical trial evaluating the Healthy Minds Program for Educators in the context of COVID-19, addressing anxiety and depression,…
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CLINICAL_TRIALS trial_result · 2022-02-07Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of JNJ-42847922 as Adjunctive Therapy to Antidepressants in Adult Participants With Major Depressive Disorder Who Have Responded Inadequately to Antidepressant Therapy [Phase 2]
A Phase 2 study evaluating JNJ-42847922 as an adjunct to antidepressants in adults with major depressive disorder who had an inadequate resp…
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CLINICAL_TRIALS trial_result · 2022-01-26Clinical Trial Update: Pathophysiology of Neurodegeneration in Late-life Depression (AV45+THK) [Phase 2]
Phase 2 trial investigating pathophysiology of neurodegeneration in late-life depression using AV45+THK.
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CLINICAL_TRIALS trial_result · 2022-01-20Clinical Trial Update: THINC-it Vortioxetine - Sensitivity to Change [Phase 2, Phase 3]
This entry reports results from Phase 2 and Phase 3 trials of vortioxetine evaluating sensitivity to cognitive change in adults with Major D…
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CLINICAL_TRIALS trial_result · 2022-01-19Clinical Trial Update: rTMS for Depressed Teens: A Sham-Controlled Trial, Part 2 [NA]
A sham-controlled trial update on repetitive transcranial magnetic stimulation (rTMS) for adolescents with major depressive disorder; the st…
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CLINICAL_TRIALS trial_result · 2022-01-19Clinical Trial Update: rTMS for Depressed Teens: A Sham-Controlled Trial, Part 1 [NA]
A sham-controlled trial of repetitive transcranial magnetic stimulation (rTMS) for adolescents with major depressive disorder was terminated…
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CLINICAL_TRIALS trial_result · 2022-01-10Clinical Trial Update: Adjunctive D-Cycloserine in Major Depressive Disorder [Phase 2]
A Phase 2 trial evaluating adjunctive D-Cycloserine for major depressive disorder has completed.
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CLINICAL_TRIALS trial_result · 2022-01-04Clinical Trial Update: Modulating Default Mode Network Function: A Transcranial Direct Current Stimulation (TDCS) Pilot Study [NA]
Pilot study evaluating transcranial direct current stimulation (TDCS) to modulate default mode network function in depression and anxiety; s…
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CLINICAL_TRIALS trial_result · 2021-12-22Clinical Trial Update: To Assess the Safety and Tolerability of an Oral Aripiprazole/Escitalopram Combination Therapy in Participants With Major Depressive Disorder (MDD) [Phase 3]
A Phase 3 trial assessing safety and tolerability of an oral aripiprazole/escitalopram combination in adults with major depressive disorder …
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CLINICAL_TRIALS trial_result · 2021-12-21Clinical Trial Update: Study to Evaluate the Efficacy, Safety and Tolerability of an Oral Aripiprazole/Escitalopram Combination Therapy in Participants With Major Depressive Disorder (MDD) [Phase 3]
Phase 3 study evaluating an oral aripiprazole/escitalopram combination for major depressive disorder was terminated; results posted in 2021.
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CLINICAL_TRIALS trial_result · 2021-12-15Clinical Trial Update: Effects of Psilocybin in Major Depressive Disorder [Phase 2]
Phase 2 trial results for psilocybin in major depressive disorder have been completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-12-13Clinical Trial Update: A CBT-based Mobile Intervention as First Line Treatment for Adolescent Depression During COVID-19 [NA]
A completed clinical trial evaluating a CBT-based mobile intervention as first-line treatment for adolescent depression during COVID-19; res…
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CLINICAL_TRIALS trial_result · 2021-12-08Clinical Trial Update: A Pilot Study on Effect of add-on Sulforaphane to SSRIs and Application of Niacin Skin Flush Response Test in Major Depressive Disorder [Phase 4]
Pilot Phase 4 study examining add-on sulforaphane to SSRIs with niacin skin flush test in major depressive disorder.
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CLINICAL_TRIALS trial_result · 2021-12-06Clinical Trial Update: A Comparative Study on Efficacy and Safety of add-on Sulforaphane or rTMS to Escitalopram for Major Depressive Disorder With Poor Response to Initial Treatment [Phase 4]
A Phase 4 clinical trial comparing add-on sulforaphane or rTMS to escitalopram for major depressive disorder with poor initial treatment res…
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CLINICAL_TRIALS trial_result · 2021-12-03Clinical Trial Update: Study of Desvenlafaxine in Treating Major Depressive Disorder. [Phase 3]
A Phase 3 clinical trial evaluating desvenlafaxine for major depressive disorder has completed.
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CLINICAL_TRIALS trial_result · 2021-12-03Clinical Trial Update: Support for Perinatal Adherence and Depression [NA]
A completed clinical trial at Massachusetts General Hospital evaluated perinatal adherence and depression in people with HIV, with results p…
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CLINICAL_TRIALS trial_result · 2021-12-01Clinical Trial Update: Remote Training in Evidence-based Practices for Clinicians Who Work With Migrant Workers [NA]
A terminated clinical trial evaluating remote training in evidence-based practices for clinicians working with migrant workers, focusing on …
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CLINICAL_TRIALS trial_result · 2021-11-30Clinical Trial Update: iTBS for Adolescent Depression: An Open Label Study Evaluating Safety and Efficacy of Treatment [NA]
Open-label study evaluating the safety and efficacy of intermittent theta-burst stimulation (iTBS) for adolescent depression; completed with…
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CLINICAL_TRIALS trial_result · 2021-11-18Clinical Trial Update: Vortioxetine as a Novel Anti-depressant With Improvement in Cognitive Abilities [Phase 3]
Phase 3 clinical trial update for vortioxetine as a novel antidepressant showing improvement in cognitive abilities.
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CLINICAL_TRIALS trial_result · 2021-11-17Clinical Trial Update: Adjunctive Pimavanserin in Subjects With Major Depressive Disorder and Inadequate Response to Antidepressant Treatment [Phase 3]
Phase 3 trial evaluating adjunctive pimavanserin for major depressive disorder with inadequate response to antidepressants has completed and…
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CLINICAL_TRIALS trial_result · 2021-11-15Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Ansofaxine Hydrochloride Extended-release Tablets in the Treatment of Major Depressive Disorder (MDD) [Phase 3]
Phase 3 trial evaluating the efficacy and safety of Ansofaxine hydrochloride extended-release tablets for major depressive disorder has been…
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CLINICAL_TRIALS trial_result · 2021-11-15Clinical Trial Update: A Trauma-Informed Approach for Positive Youth Development for Montana Students [NA]
A completed clinical trial from Montana State University investigating a trauma-informed approach to positive youth development for Montana …
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CLINICAL_TRIALS trial_result · 2021-11-12Clinical Trial Update: Study of Ammoxetine Hydrochloride Enteric-coated Tablets in Subjects With Depression [Phase 2]
Phase 2 trial update for Ammoxetine hydrochloride enteric-coated tablets in major depressive disorder is reported with unknown status.
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CLINICAL_TRIALS trial_result · 2021-11-10Clinical Trial Update: Internet-based CBT After Stroke Pilot [NA]
A completed pilot trial evaluating internet-based cognitive behavioral therapy after stroke for depression.