Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2022-11-29Clinical Trial Update: Pharmacogenetics Informed Tricyclic Antidepressant Dosing (PITA) [Phase 4]
Phase 4 trial update for pharmacogenetics-informed dosing of tricyclic antidepressants in major depressive disorder.
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CLINICAL_TRIALS trial_result · 2022-11-22Clinical Trial Update: Fixed Dose Intervention Trial of New England Enhancing Survival in SMI Patients [Phase 4]
A Phase 4 trial evaluating a fixed-dose intervention to enhance survival in patients with serious mental illness, including schizophrenia an…
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CLINICAL_TRIALS trial_result · 2022-11-10Clinical Trial Update: A Study to Evaluate the Efficacy of SAGE-217 in the Treatment of Adult Participants With Major Depressive Disorder [Phase 3]
Phase 3 trial evaluating SAGE-217 for treatment of adult major depressive disorder has completed; results posted in 2022.
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CLINICAL_TRIALS trial_result · 2022-11-03Clinical Trial Update: Study of Neural Responses Induced by Antidepressant Effects [Phase 2, Phase 3]
Phase 2/3 clinical trial investigating neural responses induced by antidepressant effects in major depressive disorder has completed with re…
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CLINICAL_TRIALS trial_result · 2022-11-03Clinical Trial Update: Reducing Health Risk Behavior and Improving Health in Adolescents With Depression [Phase 1, Phase 2]
A Phase 1/2 clinical trial aimed at reducing health risk behaviors and improving health in adolescents with depression has completed.
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CLINICAL_TRIALS trial_result · 2022-11-03Clinical Trial Update: 7-day Simvastatin and Emotional Processing [Phase 1, Phase 2]
Clinical trial update for a 7-day simvastatin intervention in depression and inflammation, completed phases 1 and 2.
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CLINICAL_TRIALS trial_result · 2022-10-25Clinical Trial Update: Efficacy, Safety and Tolerability of Cariprazine as an Adjunctive Treatment to Antidepressant Therapy (ADT) in Patients With Major Depressive Disorder (MDD) Who Have Had an Inadequate Response to Antidepressants Alone [Phase 3]
Phase 3 trial evaluating cariprazine as an adjunct to antidepressant therapy in adults with major depressive disorder after inadequate respo…
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CLINICAL_TRIALS trial_result · 2022-10-20Clinical Trial Update: A Study to Evaluate the Safety, Tolerability, and Efficacy of SAGE-217 Compared to Placebo in Adult Participants With Comorbid Major Depressive Disorder (MDD) and Insomnia [Phase 3]
Phase 3 trial for SAGE-217 in adults with comorbid Major Depressive Disorder and Insomnia was terminated; results posted in 2022.
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CLINICAL_TRIALS trial_result · 2022-10-20Clinical Trial Update: Mobile Mental Health Apps for Suicide Prevention [NA]
Completed clinical trial of mobile mental health apps for suicide prevention; results posted in 2022.
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CLINICAL_TRIALS trial_result · 2022-10-12Clinical Trial Update: A Trial of AXS-05 in Patients With Major Depressive Disorder [Phase 3]
Phase 3 trial results for AXS-05 in major depressive disorder have been completed with results posted in 2022.
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CLINICAL_TRIALS trial_result · 2022-10-12Clinical Trial Update: Open-Label Safety Study of AXS-05 in Subjects With Depression [Phase 3]
Open-label safety study of AXS-05 in subjects with depression completed; results posted in 2022.
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CLINICAL_TRIALS trial_result · 2022-10-03Clinical Trial Update: A Study to Evaluate SAGE-217 for Prevention of Relapse in Adult Participants With Major Depressive Disorder [Phase 3]
Phase 3 trial evaluating SAGE-217 (zuranolone) for prevention of relapse in adults with major depressive disorder was terminated; results po…
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CLINICAL_TRIALS trial_result · 2022-09-28Clinical Trial Update: Targeted Self-Management for Epilepsy and Serious Mental Illness (TIME) [NA]
Completed clinical trial TIME studied targeted self-management for epilepsy and serious mental illness; results posted in 2022.
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CLINICAL_TRIALS trial_result · 2022-09-27Clinical Trial Update: Screening Wizard- Phase 2 [NA]
Phase 2 clinical trial update for Screening Wizard investigating depression and suicidal ideation; study completed with results posted.
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CLINICAL_TRIALS trial_result · 2022-09-22Clinical Trial Update: Active Reference (Fluoxetine) Fixed-dose Study of Vortioxetine in Paediatric Participants Aged 7 to 11 Years With Major Depressive Disorder (MDD) [Phase 3]
Phase 3 pediatric trial updating active reference study of fixed-dose vortioxetine with fluoxetine in children aged 7-11 with major depressi…
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CLINICAL_TRIALS trial_result · 2022-09-22Clinical Trial Update: Effectiveness of a Telephone-Delivered Behavioral Treatment to Improve the Quality of Life of Older Adults With HIV [Phase 2, Phase 3]
Phase 2/3 trial assessing a telephone-delivered behavioral treatment to improve quality of life in older adults with HIV and depression; stu…
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CLINICAL_TRIALS trial_result · 2022-09-21Clinical Trial Update: The Objective of This Study is to Evaluate the Efficacy, Safety and Tolerability of Cariprazine as an Adjunctive Treatment to Antidepressant Therapy (ADT) in Patients With Major Depressive Disorder (MDD) Who Have Had an Inadequate Response to Antidepressants Alone [Phase 3]
Phase 3 trial assessing cariprazine as an adjunctive treatment to antidepressants in adults with major depressive disorder who had an inadeq…
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CLINICAL_TRIALS trial_result · 2022-09-16Clinical Trial Update: Adapting Behavioral Activation to Technology Platform [NA]
Clinical trial on adapting Behavioral Activation to a technology platform for depression has completed with results posted.
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CLINICAL_TRIALS trial_result · 2022-09-13Clinical Trial Update: Zambia Common Elements Treatment Approach Pilot Study [NA]
A pilot study update for the Zambia Common Elements Treatment Approach was terminated; results posted in 2022, investigating treatment for c…
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CLINICAL_TRIALS trial_result · 2022-09-09Clinical Trial Update: Microbiotherapy in Characterized Depressive Disorder [Phase 2]
Phase 2 clinical trial update for microbiotherapy in characterized depressive disorder is in early status with unspecified results.
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CLINICAL_TRIALS trial_result · 2022-09-08Clinical Trial Update: A Computer-Assisted CBT Tool to Enhance Fidelity in CBOCs [NA]
A completed clinical trial evaluating a computer-assisted CBT tool to improve treatment fidelity in community-based outpatient clinics for d…
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CLINICAL_TRIALS trial_result · 2022-09-08Clinical Trial Update: Ketamine and Epigenetic Aging [Phase 2]
Phase 2 clinical trial update exploring ketamine and epigenetic aging for depression and PTSD.
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CLINICAL_TRIALS trial_result · 2022-09-07Clinical Trial Update: Pentoxifylline for Treatment of Resistant Major Depression [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating pentoxifylline for treatment of resistant major depression has completed.
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CLINICAL_TRIALS trial_result · 2022-09-07Clinical Trial Update: Pentoxifylline as an Adjunct to Citalopram in Adult Patients With Major Depressive Disorder [Phase 1, Phase 2]
A clinical trial investigating pentoxifylline as an adjunct to citalopram in adults with major depressive disorder has completed phase 1 and…
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CLINICAL_TRIALS trial_result · 2022-09-07Clinical Trial Update: Multi-factor Model Constraction for Early Warning and Diagnosis of MDD [Phase 4]
Phase 4 clinical trial update on a multi-factor model for early warning and diagnosis of major depressive disorder and bipolar disorder, inc…