Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2023-03-30Clinical Trial Update: Understanding How Anaesthesia Affects ECT Outcomes [Phase 3]
Phase 3 clinical trial update examining how anesthesia affects outcomes of electroconvulsive therapy for depression; study completed.
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CLINICAL_TRIALS trial_result · 2023-03-28Clinical Trial Update: CBT Enhanced With Social Cognitive Training [NA]
A completed clinical trial evaluating CBT enhanced with social cognitive training for depression; results posted in 2023.
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CLINICAL_TRIALS trial_result · 2023-03-22Clinical Trial Update: The Safety and Efficacy of MoodElite T-4003-1 on Improving Mood in a Healthy Adult Population With Mild to Moderate Depressive Symptoms Not Eligible for Therapeutic Intervention [Phase 1, Phase 2]
A completed Phase 1/2 trial assessing safety and efficacy of MoodElite T-4003-1 for improving mood in adults with mild to moderate depressiv…
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CLINICAL_TRIALS trial_result · 2023-03-21Clinical Trial Update: PET Imaging of the Dopaminergic and Serotonergic Systems in Treated HIV Positive Subjects [Phase 1]
Phase 1 clinical trial assessing PET imaging of dopaminergic and serotonergic systems in HIV-positive individuals treated for depression; re…
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CLINICAL_TRIALS trial_result · 2023-03-21Clinical Trial Update: Low Frequency TMS for Depression in Epilepsy [NA]
Clinical trial update reporting completed study on low frequency transcranial magnetic stimulation for depression in epilepsy, with results …
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CLINICAL_TRIALS trial_result · 2023-03-14Clinical Trial Update: VITAL-DEP: Depression Endpoint Prevention in the VITamin D and OmegA-3 TriaL [NA]
VITAL-DEP reported the completion of the depression endpoint prevention analysis within the VITAL trial and posted the results. The study ev…
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CLINICAL_TRIALS trial_result · 2023-03-09Clinical Trial Update: The Study of Ammoxetine Hydrochloride Enteric-coated Tablets in Subjects With Depression [Phase 2]
Phase 2 study update for Ammoxetine Hydrochloride Enteric-coated Tablets in Major Depressive Disorder is in progress with status currently u…
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CLINICAL_TRIALS trial_result · 2023-03-02Clinical Trial Update: Canadian Biomarker Integration Network for Depression (CAN-BIND) - Validation Study [Phase 3]
Phase 3 validation study update from CAN-BIND focusing on biomarkers in major depressive disorder.
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CLINICAL_TRIALS trial_result · 2023-03-01Clinical Trial Update: Trial of the Rapid Antisuicidal Effects of Intranasal Ketamine in Comorbid Depression and Alcohol Abuse [Phase 3]
Phase 3 trial assessing rapid antisuicidal effects of intranasal ketamine in individuals with comorbid depression and alcohol use disorder c…
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CLINICAL_TRIALS trial_result · 2023-03-01Clinical Trial Update: The Sub-Saharan Africa Regional Partnership for Mental Health Capacity Building [NA]
Clinical trial update on a Sub-Saharan Africa mental health capacity-building partnership focused on depression; status completed with resul…
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CLINICAL_TRIALS trial_result · 2023-02-27Clinical Trial Update: tDCS for Increasing Exercise Adherence in Depressed Individuals [NA]
A completed clinical trial evaluating transcranial direct current stimulation (tDCS) to increase exercise adherence in individuals with depr…
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CLINICAL_TRIALS trial_result · 2023-02-24Clinical Trial Update: A Behavioral Intervention for Depression and Chronic Pain in Primary Care [NA]
A completed clinical trial evaluating a behavioral intervention for depression and chronic pain in primary care; results posted in 2023.
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CLINICAL_TRIALS trial_result · 2023-02-15Clinical Trial Update: A Long-term Comparison of Esketamine Nasal Spray Versus Quetiapine Extended Release, Both in Combination With a Selective Serotonin Reuptake Inhibitor/Serotonin-Norepinephrine Reuptake Inhibitor, in Participants With Treatment Resistant Major Depressive Disorder [Phase 3]
A Phase 3 long-term comparison of esketamine nasal spray versus quetiapine extended-release, both added to an SSRI/SNRI, in adults with trea…
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CLINICAL_TRIALS trial_result · 2023-02-10Clinical Trial Update: Stepped Care for Depression in Heart Failure [NA]
A completed clinical trial evaluating stepped care for depression in patients with heart failure; results posted in 2023.
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CLINICAL_TRIALS trial_result · 2023-02-08Clinical Trial Update: Ketamine for Older Adults Pilot [Phase 4]
Pilot Phase 4 trial investigating ketamine for treatment resistant depression in older adults has completed with results posted.
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CLINICAL_TRIALS trial_result · 2023-02-08Clinical Trial Update: A Clinical Trial of Intravenous (IV) Ganaxolone in Women With Postpartum Depression [Phase 2]
Phase 2 clinical trial of intravenous ganaxolone in women with postpartum depression has completed and results were posted.
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CLINICAL_TRIALS trial_result · 2023-02-08Clinical Trial Update: The Influence of Probiotic Supplementation on the Severity of Anxiety and Depressive Symptoms, as Well as the Function and Composition of Gut Microbiota, Metabolic, Inflammation, and Oxidative Stress Markers in Patients With Depression [Phase 2]
Phase 2 clinical trial evaluating the effects of probiotic supplementation on anxiety and depressive symptoms, gut microbiota, metabolic, in…
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CLINICAL_TRIALS trial_result · 2023-02-06Clinical Trial Update: Designing a Mental Health Model for Latina Women [NA]
A completed clinical trial focused on designing a mental health model for Latina women, with conditions including Mental Health Wellness 1 a…
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CLINICAL_TRIALS trial_result · 2023-02-01Clinical Trial Update: Does an Occupational Therapy Program Enhance Mental Health Outcomes for Veterans Who Scuba Dive [NA]
Completed clinical trial evaluating an occupational therapy program for mental health outcomes in veterans who scuba dive, with listed condi…
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CLINICAL_TRIALS trial_result · 2023-01-30Clinical Trial Update: A Clinical Trial of Oral Ganaxolone in Women With Postpartum Depression [Phase 2]
Phase 2 clinical trial of oral ganaxolone in women with postpartum depression has completed with results posted.
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CLINICAL_TRIALS trial_result · 2023-01-26Clinical Trial Update: Rapid Antidepressant Effects of Leucine [Phase 2]
Phase 2 trial investigating rapid antidepressant effects of leucine in adults with major depressive disorder; study terminated with results …
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CLINICAL_TRIALS trial_result · 2023-01-25Clinical Trial Update: A Problem Solving Intervention for Hospice Caregivers [NA]
Clinical trial on a problem-solving intervention for hospice caregivers has completed with posted results.
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CLINICAL_TRIALS trial_result · 2023-01-13Clinical Trial Update: Mindful Breathing and tDCS for Depression [NA]
A completed clinical trial investigating mindful breathing and transcranial direct current stimulation for depression; results posted in 202…
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CLINICAL_TRIALS trial_result · 2023-01-05Clinical Trial Update: Vortioxetine to Prevent Return of Symptoms in Children With Depression [Phase 3]
Phase 3 trial investigating vortioxetine to prevent relapse of depressive symptoms in children with depression; study terminated with posted…
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CLINICAL_TRIALS trial_result · 2023-01-04Clinical Trial Update: Maintenance Transcranial Magnetic Stimulation in Major Depressive Disorder [NA]
A completed clinical trial on maintenance transcranial magnetic stimulation for major depressive disorder has posted results.