Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2023-11-13Clinical Trial Update: Ketamine Treatment Effects on Synaptic Plasticity in Depression [Phase 4]
Phase 4 trial examining ketamine's effects on synaptic plasticity in major depressive disorder has completed with results posted.
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CLINICAL_TRIALS trial_result · 2023-11-09Clinical Trial Update: Efficacy and Safety of Sertraline in the Treatment of Maintenance Hemodialysis Patients With Depression [Phase 4]
Phase 4 trial assessing sertraline for efficacy and safety in maintenance hemodialysis patients with depression has completed.
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CLINICAL_TRIALS trial_result · 2023-11-07Clinical Trial Update: A Comparative Study of Sage-217 Plus an Antidepressant (ADT) Versus Placebo Plus an ADT in Adults With Major Depressive Disorder [Phase 3]
Phase 3 trial comparing Sage-217 plus an antidepressant to placebo plus an antidepressant in adults with major depressive disorder; study co…
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CLINICAL_TRIALS trial_result · 2023-11-02Clinical Trial Update: eIMPACT-DM Pilot Trial: Depression Treatment to Reduce Diabetes Risk [Phase 2]
Phase 2 pilot trial evaluating depression treatment to reduce diabetes risk has completed with results posted.
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CLINICAL_TRIALS trial_result · 2023-11-01Clinical Trial Update: Intravenous Ketamine Plus Neurocognitive Training for Depression [Phase 1, Phase 2]
A combined intravenous ketamine treatment with neurocognitive training for depression has completed Phase 1 and Phase 2 studies; results pos…
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CLINICAL_TRIALS trial_result · 2023-10-23Clinical Trial Update: Study to Assess Clinical Response of Duloxetine in Patients Hospitalized for Severe Depression [Phase 4]
Phase 4 trial update assessing duloxetine in hospitalized patients with severe depression has completed with results posted.
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CLINICAL_TRIALS trial_result · 2023-10-19Clinical Trial Update: Assessing Dopamine Transporter Occupancy in the Patients With Depression Brain With Toludesvenlafaxine Hydrochloride Extended-Release Tablets Using 11C-CFT Positron Emission Tomography (PET) [Phase 4]
Phase 4 trial assessing dopamine transporter occupancy of toludesvenlafaxine hydrochloride extended-release in patients with major depressiv…
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CLINICAL_TRIALS trial_result · 2023-10-12Clinical Trial Update: A Trial to Evaluate the Efficacy, Safety & Tolerability of Brexpiprazole in the Maintenance Treatment of Adults With Major Depressive Disorder [Phase 3]
Phase 3 trial evaluating brexpiprazole as maintenance treatment in adults with major depressive disorder has completed; results posted in 20…
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CLINICAL_TRIALS trial_result · 2023-10-12Clinical Trial Update: Evaluating a Digital Peer Mentoring Platform With College Student Populations [NA]
A completed clinical trial evaluating a digital peer mentoring platform for college students focusing on well-being, psychological health, a…
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CLINICAL_TRIALS trial_result · 2023-10-06Clinical Trial Update: Transcranial Direct Current Stimulation for the Treatment of Deficits After Traumatic Brain Injury [NA]
Clinical trial update for transcranial direct current stimulation in traumatic brain injury and related symptoms; status completed with resu…
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CLINICAL_TRIALS trial_result · 2023-10-05Clinical Trial Update: Intraoperative Ketamine Versus Saline in Depressed Patients Undergoing Anesthesia for Non-cardiac Surgery [Phase 4]
Phase 4 trial comparing intraoperative ketamine to saline in depressed patients undergoing non-cardiac surgery; results have been posted aft…
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CLINICAL_TRIALS trial_result · 2023-10-02Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Fremanezumab for Preventive Treatment of Migraine in Patients With Major Depressive Disorder [Phase 4]
Phase 4 trial evaluating fremanezumab for preventative treatment of migraine in patients with major depressive disorder has completed; resul…
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CLINICAL_TRIALS trial_result · 2023-10-02Clinical Trial Update: PEA vs. Placebo for Major Depression [Phase 2]
Phase 2 clinical trial evaluating PEA versus placebo for major depression, with bipolar depression and major depressive disorder as conditio…
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CLINICAL_TRIALS trial_result · 2023-10-02Clinical Trial Update: Stress and Inflammation in Late-Life Depression [Phase 4]
Phase 4 clinical trial update on stress and inflammation in late-life depression has completed with results posted.
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CLINICAL_TRIALS trial_result · 2023-09-28Clinical Trial Update: A Study of SLS-002 (Intranasal Racemic Ketamine) in Adults With Major Depressive Disorder at Imminent Risk of Suicide [Phase 2]
Phase 2 clinical trial of intranasal racemic ketamine (SLS-002) in adults with major depressive disorder at imminent risk of suicide has com…
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CLINICAL_TRIALS trial_result · 2023-09-28Clinical Trial Update: A Cariprazine Study in the Prevention of Relapse in Bipolar I Disorder Patients Whose Current Episode is Manic or Depressive, With or Without Mixed Features [Phase 3]
A Phase 3 trial evaluating cariprazine for preventing relapse in Bipolar I Disorder patients currently in manic or depressive episodes (with…
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CLINICAL_TRIALS trial_result · 2023-09-28Clinical Trial Update: Ketamine or Placebo in Patients With Major Depression and Advanced Cancer [Phase 1, Phase 2]
A clinical trial evaluating ketamine versus placebo for major depression in patients with advanced cancer has completed Phase 1 and Phase 2.
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CLINICAL_TRIALS trial_result · 2023-09-22Clinical Trial Update: The Effect of Probiotics on Depression Syndrome and Risk Factors of Cardiovascular Disease in Hemodialysis Patients [Phase 4]
Phase 4 trial evaluating the effect of probiotics on depression symptoms and cardiovascular risk factors in hemodialysis patients has been c…
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CLINICAL_TRIALS trial_result · 2023-09-21Clinical Trial Update: Chronic Sleep Deprivation Among the Poor: A Lab-in-the-field Approach [NA]
Completed clinical trial investigating chronic sleep deprivation effects on blood pressure and depression; results posted.
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CLINICAL_TRIALS trial_result · 2023-09-21Clinical Trial Update: Effects of Erythropoietin for Cognitive Side-effects of ECT [Phase 2]
Phase 2 trial evaluating erythropoietin for cognitive side-effects associated with electroconvulsive therapy; study completed.
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CLINICAL_TRIALS trial_result · 2023-09-18Clinical Trial Update: Open Label Ketamine Treatment for Major Depressive Disorder in Veterans [Phase 2]
Phase 2 open-label trial evaluating ketamine treatment for major depressive disorder in veterans has completed.
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CLINICAL_TRIALS trial_result · 2023-09-15Clinical Trial Update: C-STRESS: A Mental Health App for College Students With Depression [EARLY_Phase 1]
Early-phase trial updates for a mental health app (C-STRESS) targeting college students with depression and anxiety; study terminated per re…
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CLINICAL_TRIALS trial_result · 2023-09-14Clinical Trial Update: Major Depressive Disorder - Understanding The Link Between The Brain And The Heart [Phase 4]
Phase 4 clinical trial exploring connections between brain and heart in major depressive disorder has completed.
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CLINICAL_TRIALS trial_result · 2023-09-14Clinical Trial Update: An Expanded Access Protocol for Esketamine Treatment in Participants With Treatment Resistant Depression (TRD) Who do Not Have Other Treatment Alternatives [Phase 3]
Expanded access protocol for esketamine in treatment-resistant depression completed.
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CLINICAL_TRIALS trial_result · 2023-09-06Clinical Trial Update: Enhancing Well-Being Through Exercise During Old Age [NA]
A completed clinical trial investigating how exercise affects well-being in older adults with depression and osteoarthritis; results posted …