Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2023-12-29Clinical Trial Update: Bupropion Versus Escitalopram on Reward Circuitry and Motivational Deficits [Phase 4]
A Phase 4 trial comparing bupropion vs escitalopram in major depression, focusing on reward circuitry and motivational deficits; study compl…
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CLINICAL_TRIALS trial_result · 2023-12-26Clinical Trial Update: Development of a Patient Centered Mental Health Intervention for Recent Veterans [NA]
Clinical trial update on a patient-centered mental health intervention for recent veterans; trial completed with results posted in 2023.
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CLINICAL_TRIALS trial_result · 2023-12-22Clinical Trial Update: Repurposing of Dextromethorphan as an Adjunct Therapy in Patients With Major Depressive Disorder [Phase 4]
A Phase 4 clinical trial evaluating repurposing dextromethorphan as an adjunct therapy for major depressive disorder has been completed.
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CLINICAL_TRIALS trial_result · 2023-12-20Clinical Trial Update: EaseVRx-8w+ for the Treatment of Chronic Lower Back Pain [NA]
Results for the EaseVRx-8w+ VR therapy trial in chronic low back pain (with associated anxiety and depression) have been posted; the study i…
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CLINICAL_TRIALS trial_result · 2023-12-19Clinical Trial Update: Prevention of Substance Use in At-Risk Students: A Family-Centered Web Program [NA]
Clinical trial completion for a family-centered web program aimed at preventing substance use in at-risk students; results posted in 2023.
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CLINICAL_TRIALS trial_result · 2023-12-18Clinical Trial Update: Toward Understanding Drivers of Patient Engagement With Digital Mental Health Interventions - Part I [NA]
A completed clinical trial update studying drivers of patient engagement with digital mental health interventions for depression and anxiety…
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CLINICAL_TRIALS trial_result · 2023-12-18Clinical Trial Update: Behavioral Activation and Medication Optimization for Perioperative Mental Health Feasibility Study [NA]
Feasibility study on behavioral activation and medication optimization to support perioperative mental health in older adults undergoing var…
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CLINICAL_TRIALS trial_result · 2023-12-15Clinical Trial Update: Summative Assessment of the BurntOut 3D Simulation With Medical Students [NA]
A completed clinical trial investigating a 3D simulation tool (BurntOut 3D) for medical students addressing burnout and related factors, wit…
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CLINICAL_TRIALS trial_result · 2023-12-15Clinical Trial Update: Brain Insulin Resistance in Mood Disorders [Phase 1, Phase 2]
Clinical trial update on intranasal insulin targeting brain insulin resistance in mood disorders, spanning Phase 1 and Phase 2 for major dep…
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CLINICAL_TRIALS trial_result · 2023-12-14Clinical Trial Update: Depression Treatment and Risk for Cardiovascular Disease [Phase 1, Phase 2]
A completed Phase 1/2 clinical trial evaluating a depression treatment and its impact on cardiovascular risk.
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CLINICAL_TRIALS trial_result · 2023-12-14Clinical Trial Update: Stay Connected: Testing an Intervention to Combat Coronavirus-related Social Isolation Among Older Adults [NA]
A completed clinical trial studying an intervention to reduce social isolation in older adults facing coronavirus-related loneliness, with r…
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CLINICAL_TRIALS trial_result · 2023-12-12Clinical Trial Update: iTBS in Refractory Pediatric Depression [NA]
Clinical trial update for iTBS in refractory pediatric depression; study terminated with results posted.
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CLINICAL_TRIALS trial_result · 2023-12-12Clinical Trial Update: Opioid Treatment and Recovery Through a Safe Pain Management Program [NA]
ClinicalTrials.gov update shows the study 'Opioid Treatment and Recovery Through a Safe Pain Management Program' has completed and posted re…
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CLINICAL_TRIALS trial_result · 2023-12-08Clinical Trial Update: COMRADE: Collaborative Care Management for Distress and Depression in Rural Diabetes [NA]
Completed clinical trial evaluating collaborative care management for distress and depression in rural diabetes patients; results posted.
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CLINICAL_TRIALS trial_result · 2023-12-05Clinical Trial Update: A Study to Evaluate the Efficacy of Sage-217 in the Treatment of Adult Participants With Major Depressive Disorder (MDD) [Phase 3]
Phase 3 trial assessing the efficacy of Sage-217 in adults with major depressive disorder completed with results posted in 2023.
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CLINICAL_TRIALS trial_result · 2023-12-01Clinical Trial Update: ALTO-100 in MDD and/or PTSD [Phase 2]
A Phase 2 clinical trial update for ALTO-100 in major depressive disorder and post-traumatic stress disorder has completed.
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CLINICAL_TRIALS trial_result · 2023-11-29Clinical Trial Update: Evaluation of Psilocybin-Assisted Psychotherapy in Treating Severe Depression in Patients With PTSD [Phase 2]
Phase 2 trial evaluating psilocybin-assisted psychotherapy for severe depression in patients with PTSD is in progress with status not disclo…
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CLINICAL_TRIALS trial_result · 2023-11-28Clinical Trial Update: Placebo-Controlled Study of ONO-2333Ms in Patients With Recurrent Major Depressive Disorder [Phase 2]
A Phase 2 placebo-controlled trial of ONO-2333Ms in patients with recurrent major depressive disorder has completed.
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CLINICAL_TRIALS trial_result · 2023-11-28Clinical Trial Update: The Safety and Efficacy of Fecal Microbiota Transplantation in a Population With Major Depressive Disorder [Phase 2, Phase 3]
Phase 2/3 clinical trial investigating the safety and efficacy of fecal microbiota transplantation in individuals with major depressive diso…
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CLINICAL_TRIALS trial_result · 2023-11-24Clinical Trial Update: THRIVE Feasibility Trial [Phase 3]
A Phase 3 feasibility trial called THRIVE completed, investigating surgical and anesthesia-related outcomes.
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CLINICAL_TRIALS trial_result · 2023-11-22Clinical Trial Update: Collaborative Depression Care Management in Treating Depressed Low-income Hispanics With Diabetes [Phase 4]
Phase 4 clinical trial update evaluating collaborative depression care management in depressed low-income Hispanic individuals with diabetes…
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CLINICAL_TRIALS trial_result · 2023-11-18Clinical Trial Update: Measuring Blood Flow in the Brain After Epileptic Activity [Phase 2]
Phase 2 clinical trial update evaluating blood flow measurement in the brain following epileptic activity.
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CLINICAL_TRIALS trial_result · 2023-11-15Clinical Trial Update: Rapid Improvement of Depression of Fluoxetine Combined With ATP [Phase 2]
Phase 2 clinical trial investigating rapid improvement of depression with fluoxetine combined with ATP.
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CLINICAL_TRIALS trial_result · 2023-11-15Clinical Trial Update: Effect of Medical Marijuana on Neurocognition and Escalation of Use [NA]
Clinical trial update on the effects of medical marijuana on neurocognition and escalation of use; study completed with results posted in 20…
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CLINICAL_TRIALS trial_result · 2023-11-14Clinical Trial Update: The Role of Negr1 In Modulating Neuroplasticity in Major Depression (RONIN) [Phase 4]
Phase 4 clinical trial update investigating Negr1's role in neuroplasticity for major depressive disorder and bipolar depression, status cur…