Major Depressive Disorder
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CLINICAL_TRIALS trial_result · 2024-04-30Clinical Trial Update: ALTO-300 in Depression [Phase 2]
ALTO-300's Phase 2 trial for Major Depressive Disorder has completed. The update does not include results in the provided snippet.
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CLINICAL_TRIALS trial_result · 2024-04-29Clinical Trial Update: A Long-Term Study of Brexpiprazole in Patients With Major Depressive Disorder [Phase 3]
A Phase 3 long-term study of brexpiprazole in adults with major depressive disorder has completed, with results posted in April 2024.
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CLINICAL_TRIALS trial_result · 2024-04-29Clinical Trial Update: Efficacy and Safety of Toludesvenlafaxine Hydrochloride Sustained-release Tablets Versus Desvenlafaxine Succinate Sustained-release Tablets Targeting Anhedonia in Patients With Major Depression Disorder [NA]
This clinical trial compares toludesvenlafaxine hydrochloride sustained-release tablets against desvenlafaxine succinate sustained-release t…
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CLINICAL_TRIALS trial_result · 2024-04-26Clinical Trial Update: ALTO-300 in Depression (ALTO-300-004) [Phase 2]
ALTO-300-004, a Phase 2 trial in Major Depressive Disorder, has completed enrollment and its study status.
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CLINICAL_TRIALS trial_result · 2024-04-23Clinical Trial Update: Spinal Cord Stimulation for the Treatment of Major Depressive Disorder [Phase 1, Phase 2]
Completed Phase 1 and Phase 2 clinical trials evaluating spinal cord stimulation for major depressive disorder, with results posted.
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CLINICAL_TRIALS trial_result · 2024-04-19Clinical Trial Update: The Effect of Psilocybin on MDD Symptom Severity and Synaptic Density [Phase 2]
A Phase 2 clinical trial evaluating the effect of psilocybin on symptom severity and synaptic density in major depressive disorder.
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CLINICAL_TRIALS trial_result · 2024-04-18Clinical Trial Update: A Study of Xiongdan Wan Treating Depression [Phase 2]
Phase 2 clinical trial completed examining Xiongdan Wan for major depressive disorder.
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CLINICAL_TRIALS trial_result · 2024-04-18Clinical Trial Update: Middle School Success Over Stress [NA]
A completed clinical trial from the University of Oregon evaluated a program addressing parenting and parent-child relations, with results p…
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CLINICAL_TRIALS trial_result · 2024-04-17Clinical Trial Update: Study to Evaluate the Efficacy and Safety of 3 Fixed Doses of Intranasal Esketamine in Addition to Comprehensive Standard of Care for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Pediatric Participants Assessed to be at Imminent Risk for Suicide [Phase 2]
Phase 2 trial evaluating three fixed doses of intranasal esketamine added to comprehensive standard of care for rapid reduction of symptoms …
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CLINICAL_TRIALS trial_result · 2024-04-11Clinical Trial Update: Buspirone and Melatonin for Depression Following Traumatic Brain Injury [Phase 4]
Phase 4 trial evaluating buspirone and melatonin for Depression following traumatic brain injury; recruiting.
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CLINICAL_TRIALS trial_result · 2024-04-09Clinical Trial Update: OptimizeD Pilot Study [Phase 3]
Phase 3 pilot study update for OptimizeD completed, investigating depression and depressive disorder.
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CLINICAL_TRIALS trial_result · 2024-04-08Clinical Trial Update: Deep Brain Stimulation for Major Depressive Disorder [NA]
Clinical trial update indicates termination of a deep brain stimulation study for major depressive disorder with results posted.
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CLINICAL_TRIALS trial_result · 2024-04-02Clinical Trial Update: Mini Theta Burst TMS in MDD Patients [NA]
A completed clinical trial report on mini theta burst TMS in patients with Major Depressive Disorder; results posted in 2024.
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CLINICAL_TRIALS trial_result · 2024-04-01Clinical Trial Update: A Double-blind, Placebo-controlled Study of Antidepressant Augmentation With Agomelatine [Phase 4]
A Phase 4 randomized, double-blind, placebo-controlled trial evaluated augmentation with agomelatine in adults with major depressive disorde…
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CLINICAL_TRIALS trial_result · 2024-03-27Clinical Trial Update: SPL026 (DMT Fumarate) in Healthy Subjects and MDD Patients [Phase 1, Phase 2]
Clinical Trial Update reports phase 1/2 study of SPL026 (DMT Fumarate) in healthy subjects and patients with Major Depressive Disorder, with…
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CLINICAL_TRIALS trial_result · 2024-03-26Clinical Trial Update: A Study to Assess the Efficacy and Safety of REL-1017 as Adjunctive Treatment for Major Depressive Disorder (MDD) [Phase 3]
Phase 3 trial evaluating REL-1017 as adjunctive therapy for major depressive disorder; results and safety data were posted in 2024.
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CLINICAL_TRIALS trial_result · 2024-03-26Clinical Trial Update: A Study to Assess the Efficacy and Safety of REL-1017 as Monotherapy for Major Depressive Disorder (MDD) [Phase 3]
Phase 3 trial assessing REL-1017 as monotherapy for major depressive disorder has been completed with results posted.
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CLINICAL_TRIALS trial_result · 2024-03-25Clinical Trial Update: A Study of a Psilocybin Analog (CYB003) in Healthy Participants With and Without Major Depressive Disorder [Phase 1, Phase 2]
A clinical trial update for CYB003 (a psilocybin analog) in healthy participants with and without major depressive disorder, covering Phase …
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CLINICAL_TRIALS trial_result · 2024-03-25Clinical Trial Update: Self-Management of Chronic Depressive Symptoms in Pregnancy [NA]
A completed clinical trial investigating self-management of chronic depressive symptoms in pregnancy was conducted, with results posted.
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CLINICAL_TRIALS trial_result · 2024-03-20Clinical Trial Update: Altering Default Mode Network Activity With Transcranial Focused Ultrasound to Reduce Depressive Symptoms [Phase 1, Phase 2]
A Phase 1/2 clinical trial investigating focused ultrasound targeting the default mode network to reduce depressive symptoms.
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CLINICAL_TRIALS trial_result · 2024-03-19Clinical Trial Update: Personalized Treatments for Depressive Symptoms in Patients With Advanced Heart Failure [Phase 4]
Phase 4 clinical trial update on personalized treatments for depressive symptoms in patients with advanced heart failure has completed with …
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CLINICAL_TRIALS trial_result · 2024-03-19Clinical Trial Update: Theta Burst Stimulation in Young Adults With Depression [NA]
Clinical trial update reporting completion and results for theta burst stimulation in young adults with depression.
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CLINICAL_TRIALS trial_result · 2024-03-18Clinical Trial Update: Collaborative Care for Women Veterans [NA]
A completed clinical trial update on collaborative care for women veterans addressing anxiety and depression; results posted in 2024.
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CLINICAL_TRIALS trial_result · 2024-03-15Clinical Trial Update: Improving Outcomes for Older Veterans With Chronic Back Pain and Depression [NA]
A completed clinical trial investigating outcomes for older veterans with chronic back pain and depression; results posted in 2024.
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CLINICAL_TRIALS trial_result · 2024-03-15Clinical Trial Update: Effectiveness of Ketamine Treatment for Three Consecutive Days in Depression [Phase 4]
A Phase 4 clinical trial evaluating the effectiveness of ketamine treatment administered over three consecutive days in patients with depres…