Major Depressive Disorder
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CLINICAL_TRIALS trial_result · 2026-04-22Clinical Trial Update: Empower: tDCS for Major Depressive Disorder at Home [NA]
A completed clinical trial evaluating the Empower tDCS device for home use in adults with Major Depressive Disorder, with results posted on …
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CLINICAL_TRIALS trial_result · 2026-04-22Clinical Trial Update: MOCHA: Embedded Inpatient Mental Health Care for High-Risk Perinatal Patients
ClinicalTrials.gov entry for the MOCHA study describes an embedded inpatient mental health program for high-risk perinatal patients. The tri…
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CLINICAL_TRIALS trial_result · 2026-04-21Clinical Trial Update: Attachment and Biobehavioral Catch-up and Depression Treatment [NA]
Clinical trial update for Attachment and Biobehavioral Catch-up and Depression Treatment conducted by University of California, San Francisc…
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CLINICAL_TRIALS trial_result · 2026-04-21Clinical Trial Update: PRISM for Depression and Anxiety in Young Adults With Cancer [NA]
PRISM is a trial evaluating depression and anxiety in young adults with cancer; the study has completed.
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CLINICAL_TRIALS trial_result · 2026-04-21Clinical Trial Update: ANTIVIRAL TREATMENT OF CYTOMEGALOVIRUS IN DEPRESSION [Phase 1, Phase 2]
A Phase 1/2 clinical trial testing an antiviral treatment for cytomegalovirus in Major Depressive Disorder has completed.
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CLINICAL_TRIALS trial_result · 2026-04-21Clinical Trial Update: IPT for Major Depression Following Perinatal Loss: Healing After Loss (HeAL) [NA]
A completed clinical trial evaluating interpersonal psychotherapy for major depressive disorder following perinatal loss (HeAL).
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CLINICAL_TRIALS trial_result · 2026-04-21Clinical Trial Update: Oral Aspirin + Ketamine as Adjunct to Oral Antidepressant Therapy for Depression [Phase 4]
Phase 4 clinical trial assessing oral aspirin plus ketamine as an adjunct to standard antidepressant therapy for treatment-resistant depress…
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CLINICAL_TRIALS trial_result · 2026-04-20Clinical Trial Update: HIV Engagement and Adolescent Depression Support (HEADS-UP) [NA]
A completed UNC-led clinical trial evaluating HIV engagement and support for adolescents with depression and anxiety.
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CLINICAL_TRIALS trial_result · 2026-04-20Clinical Trial Update: Pharmacokinetics, Safety, Tolerability and Efficacy of a Subcutaneous Long-Acting Injection of Cariprazine (Cariprazine Depot) in Subjects Eligible for Treatment With Oral Cariprazine [Phase 1, Phase 2]
The update covers a subcutaneous long-acting cariprazine depot studied in Phase 1/2 for pharmacokinetics, safety, tolerability, and efficacy…
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CLINICAL_TRIALS trial_result · 2026-04-20Clinical Trial Update: Therapeutic Touch and Acupressure on Depressive Symptoms [NA]
Completed clinical trial evaluating therapeutic touch and acupressure for depressive symptoms; the update does not provide efficacy or safet…
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CLINICAL_TRIALS trial_result · 2026-04-20Clinical Trial Update: Mobile Mental Health Stigma Reduction Intervention Among Black Adults [NA]
This entry reports the status of a clinical trial evaluating a mobile intervention aimed at reducing mental health stigma among Black adults…
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CLINICAL_TRIALS trial_result · 2026-04-20Clinical Trial Update: A Phase I/II Study of PDC-1421 for Treating Depression in Cancer Patients [Phase 1, Phase 2]
A Phase I/II clinical trial evaluating PDC-1421 for major depressive disorder in cancer patients; recruitment status is not yet recruiting.
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CLINICAL_TRIALS trial_result · 2026-04-20Clinical Trial Update: Dyadic Interactions in Depressed and Non-Depressed Mothers and Their Infants
A completed NICHD clinical trial examined mother-infant dyadic interactions in the context of maternal depression.
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CLINICAL_TRIALS trial_result · 2026-04-17Clinical Trial Update: PD, PK, and Safety of ALTO-203 in Patients With MDD [Phase 2]
Phase 2 study evaluating pharmacodynamics, pharmacokinetics, and safety of ALTO-203 in patients with Major Depressive Disorder has completed…
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CLINICAL_TRIALS trial_result · 2026-04-17Clinical Trial Update: A Multiple Case Study of Schema Therapy for Difficult-to-treat Depression- DEPRE-ST*Case [NA]
A completed clinical trial using a multiple case study design to examine schema therapy for difficult-to-treat depression. The study status …
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CLINICAL_TRIALS trial_result · 2026-04-17Clinical Trial Update: Effectiveness of Behavioral Activation Group Therapy for Patients With Depression at the Community in Thanh Hoa [NA]
Clinical trial update indicating completion of a study assessing the effectiveness of Behavioral Activation Group Therapy for patients with …
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CLINICAL_TRIALS trial_result · 2026-04-16Clinical Trial Update: Using Technology to Optimize Collaborative Care Management of Depression in Urban and Rural Cancer Centers, SCOPE [NA]
This terminated University of Washington clinical trial tested technology-driven collaborative care for depression among cancer patients in …
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CLINICAL_TRIALS trial_result · 2026-04-15Clinical Trial Update: Trial of Transcranial Photobiomodulation for Depression With PET and EEG Outcomes [NA]
A completed clinical trial evaluating transcranial photobiomodulation for depression, with PET and EEG outcomes.
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CLINICAL_TRIALS trial_result · 2026-04-15Clinical Trial Update: Postoperative Anxiety and Depression Among Chinese Elderly Patients
A completed clinical trial conducted at Chinese PLA General Hospital investigated postoperative anxiety and depression in elderly Chinese pa…
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CLINICAL_TRIALS trial_result · 2026-04-15Clinical Trial Update: A Study of Aticaprant in Adult and Elderly Participants With Major Depressive Disorder (MDD) [Phase 3]
Phase 3 study of Aticaprant for major depressive disorder has been terminated, according to the trial record.
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CLINICAL_TRIALS trial_result · 2026-04-15Clinical Trial Update: Green VR for Depression [NA]
A completed clinical trial evaluating the Green VR intervention for depression of mild to moderate severity.
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CLINICAL_TRIALS trial_result · 2026-04-14Clinical Trial Update: VR-Moodboost; an Innovative Virtual Reality Treatment for Adolescents With Depression [NA]
A completed clinical trial evaluating VR-Moodboost, a virtual reality treatment for adolescents with major depressive disorder.
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Reducing Suicide Risk in Adolescents and Young Adults Via a Psychobehavioral Intervention to Regularize Daily Rhythms [NA]
A completed clinical trial evaluated a psychobehavioral intervention aimed at regularizing daily rhythms to reduce suicide risk in adolescen…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Closed-loop Optimized rTMS for Depression [Phase 1]
A Phase 1 trial evaluating a closed-loop optimized repetitive transcranial magnetic stimulation (rTMS) approach for major depressive disorde…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Electroconvulsive Therapy Versus Intravenous Ketamine in Treatment-Resistant Major Depressive Disorder [NA]
A completed clinical trial compared electroconvulsive therapy with intravenous ketamine for treatment-resistant major depressive disorder.