Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-02-10Clinical Trial Update: You Are What You Eat: Food As a Risk Factor and a Treatment for Depression [NA]
This completed University of Michigan clinical trial investigates whether diet influences depression risk and whether dietary interventions …
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CLINICAL_TRIALS trial_result · 2025-02-10Clinical Trial Update: Efficacy and Safety Study of NeuroStar TMS Therapy in Patients With Major Depressive Disorder With Postpartum Onset [NA]
A clinical trial evaluating NeuroStar TMS Therapy for major depressive disorder with postpartum onset was terminated, with results subsequen…
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CLINICAL_TRIALS trial_result · 2025-02-07Clinical Trial Update: Alpha-Amino-3-Hydroxy-5-Methyl-4- Isoxazole Propionic Acid Receptor Components of the Anti-Depressant Ketamine Response, Pilot Trial [Phase 1]
This update reports the completion of a Phase 1 pilot trial investigating AMPA receptor components in the antidepressant response to ketamin…
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CLINICAL_TRIALS trial_result · 2025-02-05Clinical Trial Update: Healthy Expectations - a Program for Pregnant Women Experiencing Depressive Symptoms [NA]
The Healthy Expectations trial, a program for pregnant women experiencing depressive symptoms, has completed.
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CLINICAL_TRIALS trial_result · 2025-02-05Clinical Trial Update: A Personalized Approach to Effects of Affective Bias Modification on Symptom Change and Rumination [NA]
This clinical trial update reports completed results for a study exploring personalized effects of affective bias modification on symptoms a…
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CLINICAL_TRIALS trial_result · 2025-02-04Clinical Trial Update: RTMS Feasibility Study on Adolescent Depression Stimulation [NA]
A completed feasibility study evaluating repetitive transcranial magnetic stimulation (RTMS) for adolescent depression.
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CLINICAL_TRIALS trial_result · 2025-02-04Clinical Trial Update: A Systems-Level Intervention for Rural Adults With Depression [NA]
University of Michigan completed a systems-level intervention trial for rural adults with depressive symptoms; results have been posted.
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CLINICAL_TRIALS trial_result · 2025-02-03Clinical Trial Update: rTMS for MDD: 5.5cm Rule vs. F3 Targeting [NA]
Completed study comparing 5.5 cm rule versus F3 targeting for repetitive transcranial magnetic stimulation (rTMS) in major depressive disord…
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CLINICAL_TRIALS trial_result · 2025-02-03Clinical Trial Update: Reducing Depression and Anxiety Among Teens [NA]
A completed clinical trial update from Aga Khan University investigating approaches to reduce depression and anxiety among teenagers; the do…
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CLINICAL_TRIALS trial_result · 2025-02-03Clinical Trial Update: The Effects of Videogames on Depression Symptoms and Brain Dynamics [NA]
The study by Aalto University has completed evaluating the effects of videogames on depressive symptoms and brain dynamics in individuals wi…
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CLINICAL_TRIALS trial_result · 2025-02-03Clinical Trial Update: Clinical Investigation of Wysa [NA]
Completed clinical trial evaluating Wysa for mental health issues including anxiety and depressive symptoms. Results were posted on 2025-02-…
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CLINICAL_TRIALS trial_result · 2025-02-03Clinical Trial Update: Study to Evaluate Potential Predictors of Relapse in Participants With Major Depressive Disorder (MDD)
This clinical trial update reports that the Janssen-sponsored study examining potential predictors of relapse in adults with major depressiv…
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CLINICAL_TRIALS trial_result · 2025-01-31Clinical Trial Update: Mechanisms of Mindfulness-based Interventions
This Vanderbilt University Medical Center clinical trial explored the mechanisms of mindfulness-based interventions in depression, anxiety, …
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CLINICAL_TRIALS trial_result · 2025-01-31Clinical Trial Update: A Transdiagnostic Course for Common Mental Health Problems in Primary Care [NA]
Completed trial evaluating a transdiagnostic course for depression and anxiety in primary care; results were posted on 2025-01-31.
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CLINICAL_TRIALS trial_result · 2025-01-30Clinical Trial Update: Implementing and Evaluating an Internet-based Cognitive Behavior Therapy Intervention in School Settings [NA]
A Montana State University–led clinical trial evaluated an internet-based cognitive behavior therapy program implemented in school settings …
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CLINICAL_TRIALS trial_result · 2025-01-30Clinical Trial Update: Pharmacogenomic Testing to Personalize Supportive Oncology [NA]
This completed clinical trial from Wake Forest University Health Sciences evaluated pharmacogenomic testing to personalize supportive oncolo…
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CLINICAL_TRIALS trial_result · 2025-01-30Clinical Trial Update: Adverse Drug Reactions to Cancer Therapies in Patients with Depression: Insights from VigiBase
This clinical trial update summarizes adverse drug reactions observed with cancer therapies in patients who have depression, using insights …
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CLINICAL_TRIALS trial_result · 2025-01-30Clinical Trial Update: Exploration of Differences in Metabolite Concentrations by NMR Spectroscopy in the Ventral Striatum, Anterior Cingulate Cortex and Prefrontal Cortex in Euthymic Patients With Unipolar and Bipolar Type II Mood Disorders, as Well as in Healthy Subjects [NA]
A completed clinical trial comparing brain metabolite patterns among euthymic individuals with bipolar disorder type II, major depressive di…
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CLINICAL_TRIALS trial_result · 2025-01-30Clinical Trial Update: Investigating LIFUP in Anhedonic Depression [NA]
A UCLA-sponsored clinical trial evaluating low-intensity focused ultrasound (LIFUP) for anhedonic depression has completed.
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CLINICAL_TRIALS trial_result · 2025-01-29Clinical Trial Update: MBCT Via Group Videoconferencing for Acute Coronary Syndrome Patients With Depressive Symptoms: A Pilot RCT [NA]
A pilot randomized controlled trial evaluating mindfulness-based cognitive therapy delivered via group videoconferencing for depressive symp…
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CLINICAL_TRIALS trial_result · 2025-01-29Clinical Trial Update: High Dose Accelerated iTBS for Depression [NA]
Completed clinical trial evaluating high-dose accelerated intermittent theta-burst stimulation (iTBS) for major depressive disorder.
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CLINICAL_TRIALS trial_result · 2025-01-29Clinical Trial Update: Single-dose Ketamine Treatment to Improve Depression in Mild Cognitive Impairment [Phase 2]
A Phase 2 clinical trial evaluating a single-dose ketamine treatment to improve depressive symptoms in individuals with mild cognitive impai…
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CLINICAL_TRIALS trial_result · 2025-01-28Clinical Trial Update: The Relationship Between Diaphragm Muscle Thickness and Fibromyalgia
The completed clinical trial investigated the relationship between diaphragm muscle thickness and fibromyalgia, including associated anxiety…
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CLINICAL_TRIALS trial_result · 2025-01-27Clinical Trial Update: Supportive and Supportive-Expressive Treatment for Depression [NA]
The clinical trial evaluating supportive and supportive-expressive therapy for major depressive disorder has completed. Results have been po…
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CLINICAL_TRIALS trial_result · 2025-01-24Clinical Trial Update: Preventing Internalizing in Preadolescents Exposed to Chronic Stress [NA]
This clinical trial update reports a completed study by Penn State University focusing on preventing internalizing symptoms (anxiety and dep…