Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-03-28Clinical Trial Update: Treating Depression With Text Messaging [NA]
A completed clinical trial from the University of Tennessee evaluated treating moderate depression with a text messaging intervention.
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CLINICAL_TRIALS trial_result · 2025-03-27Clinical Trial Update: Vagus Nerve Stimulation: Integration of Behavior and Cardiac Modulation [NA]
Clinical trial evaluating the integration of behavioral approaches with vagus nerve stimulation for Major Depressive Disorder has completed …
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CLINICAL_TRIALS trial_result · 2025-03-27Clinical Trial Update: PERsonalized Mood Augmentation Trial for Depressed Mood [NA]
This clinical trial update indicates that the PERsonalized Mood Augmentation Trial for depressed mood has completed.
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CLINICAL_TRIALS trial_result · 2025-03-27Clinical Trial Update: Dose-Response Effect Exercise and Depression [NA]
This clinical trial update reports a completed study evaluating the dose-response effect of exercise on depression, sponsored by the Univers…
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CLINICAL_TRIALS trial_result · 2025-03-27Clinical Trial Update: Tai Chi Versus Conventional Exercise to Alleviate Depression in Insomniacs [NA]
A completed clinical trial evaluating Tai Chi versus conventional exercise for reducing depressive symptoms in adults with chronic insomnia.
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CLINICAL_TRIALS trial_result · 2025-03-27Clinical Trial Update: Adherence to Antidepressants During Pregnancy
A completed clinical trial evaluated adherence to antidepressant treatment among pregnant women. The study was conducted by Assistance Publi…
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CLINICAL_TRIALS trial_result · 2025-03-26Clinical Trial Update: Zuranolone Pharmacokinetics (PK) and Safety Study Adolescent Participants With Major Depressive Disorder (MDD) [Phase 1]
This document reports a Phase 1 pharmacokinetics and safety study of zuranolone in adolescent participants with major depressive disorder.
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CLINICAL_TRIALS trial_result · 2025-03-26Clinical Trial Update: Collaborative Stepped-Care and Productive Ageing Program for Older People With Depressive Symptoms [NA]
Completed clinical trial evaluating a collaborative stepped-care and productive ageing program for older people with depressive symptoms.
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CLINICAL_TRIALS trial_result · 2025-03-25Clinical Trial Update: Multicenter Study of Lumateperone as Adjunctive Therapy in the Treatment of Patients With Major Depressive Disorder [Phase 3]
A Phase 3 multicenter trial evaluating lumateperone as adjunctive therapy for adults with major depressive disorder has completed and result…
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CLINICAL_TRIALS trial_result · 2025-03-25Clinical Trial Update: Depressive State After Sleeve Gastrectomy
This ClinicalTrials.gov entry reports a completed study investigating depressive states following sleeve gastrectomy in individuals with mor…
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CLINICAL_TRIALS trial_result · 2025-03-25Clinical Trial Update: Psychophysiological Study of Pain Perception in Depressed Patients With Suicidal Risk [NA]
This clinical trial update concerns a psychophysiological study of pain perception in patients with major depressive disorder and suicidal r…
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CLINICAL_TRIALS trial_result · 2025-03-24Clinical Trial Update: A Scalable Psychological Intervention for Earthquake Survivors in Türkiye [NA]
A completed clinical trial evaluating a scalable psychological intervention for earthquake survivors in Türkiye, focusing on reducing psycho…
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CLINICAL_TRIALS trial_result · 2025-03-24Clinical Trial Update: Use of a Digitally Enabled App With Clinical Team Interface in the Management of Depression [NA]
This clinical trial update reports results from a completed study evaluating a digitally enabled app with a clinical team interface for mana…
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CLINICAL_TRIALS trial_result · 2025-03-24Clinical Trial Update: SAINT for MDD in an Inpatient Setting Follow-on [Phase 2, Phase 3]
A Phase 2/3 clinical trial of the SAINT approach for major depressive disorder in an inpatient setting has been terminated.
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CLINICAL_TRIALS trial_result · 2025-03-24Clinical Trial Update: The Effects of SAINT® Neuromodulation System on Explicit and Implicit Suicidal Cognition [Phase 2, Phase 3]
Phase 2 and Phase 3 trials of the SAINT Neuromodulation System for Major depressive disorder have been terminated, including consideration o…
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CLINICAL_TRIALS trial_result · 2025-03-24Clinical Trial Update: Cancer Caregiver Burden: Targeting Emotion Regulation in a Trial [NA]
Completed clinical trial from the University of Aarhus evaluating an emotion-regulation intervention to reduce caregiver burden in cancer ca…
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CLINICAL_TRIALS trial_result · 2025-03-20Clinical Trial Update: The BIomarker Guided (BIG) Study for Depression [Phase 4]
Phase 4 biomarker-guided study in major depressive disorder has completed and posted results.
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CLINICAL_TRIALS trial_result · 2025-03-20Clinical Trial Update: Group Therapy for Women Prisoners With Comorbid Substance Use and Depression [NA]
Completed clinical trial evaluating group therapy for women prisoners with co-occurring substance use disorders and depression.
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CLINICAL_TRIALS trial_result · 2025-03-19Clinical Trial Update: Clinical Trial Evaluating Lumateperone Monotherapy in the Treatment of Bipolar Depression or Major Depressive Disorder [Phase 3]
Clinical trial update reports completion of a Phase 3 study evaluating lumateperone as monotherapy in bipolar depression and major depressiv…
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CLINICAL_TRIALS trial_result · 2025-03-19Clinical Trial Update: Evaluation of a Training Course for Educational Professionals [NA]
A completed trial evaluating a training course for educational professionals aimed at addressing depression in children and adolescents.
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CLINICAL_TRIALS trial_result · 2025-03-18Clinical Trial Update: Frontline Clinician Psilocybin Study [Phase 3]
Phase 3 trial evaluating psilocybin for burnout in frontline clinicians has completed, with results posted in 2025. The study also explored …
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CLINICAL_TRIALS trial_result · 2025-03-18Clinical Trial Update: Healthy Lifestyle Intervention for High-Risk Minority Pregnant Women [NA]
A completed clinical trial evaluated a healthy lifestyle intervention for high-risk minority pregnant women; results have been posted.
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CLINICAL_TRIALS trial_result · 2025-03-17Clinical Trial Update: Efficacy of the Mobile Application for Prediction and Prevention of Mood Episode Recurrence Based on Machine Learning [NA]
A completed clinical trial evaluating the efficacy of a machine-learning-based mobile app to predict and prevent mood episode recurrence in …
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CLINICAL_TRIALS trial_result · 2025-03-17Clinical Trial Update: Providing Mental Health Precision Treatment [NA]
A completed University of Michigan mental health precision treatment trial has posted results, involving depression, addiction (substance us…
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CLINICAL_TRIALS trial_result · 2025-03-17Clinical Trial Update: Computer-assisted Cognitive-Behavior Therapy for Depression in Primary Care [NA]
This clinical trial update notes a completed study evaluating computer-assisted cognitive-behavioral therapy for depression in primary care.