Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-05-14Clinical Trial Update: Depression and Anxiety Among Chronic Pain Patients in the Netherlands
A clinical trial conducted at Amsterdam UMC (VUmc) evaluating chronic pain with comorbid depression and anxiety has completed.
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CLINICAL_TRIALS trial_result · 2025-05-14Clinical Trial Update: IM Ketamine vs Midazolam for Suicidal ER Patients [Phase 4]
A Phase 4 randomized trial comparing intramuscular ketamine to midazolam for emergency department patients with depression and suicidal idea…
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CLINICAL_TRIALS trial_result · 2025-05-14Clinical Trial Update: Decision Making Tool for Firearm Storage [NA]
This clinical trial update reports on a completed study evaluating a decision-making tool for firearm storage intended for individuals with …
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CLINICAL_TRIALS trial_result · 2025-05-14Clinical Trial Update: Treatment Interrupts Depression Early [Phase 2]
A Phase 2 trial evaluating treatment interruption for depression is currently recruiting in Nova Scotia.
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CLINICAL_TRIALS trial_result · 2025-05-13Clinical Trial Update: Effects of Schema Therapy vs. Cognitive Behavioral Therapy vs. Individual Supportive Therapy [NA]
A completed clinical trial compared schema therapy, cognitive behavioral therapy, and individual supportive therapy for major depressive dis…
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CLINICAL_TRIALS trial_result · 2025-05-13Clinical Trial Update: NQ TMS for MDD Therapy Using 1 Day x 3 Sessions Protocol for Adult Patient [NA]
A completed clinical trial update for NQ TMS therapy in adults with Major Depressive Disorder using a 1-day, 3-session protocol.
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CLINICAL_TRIALS trial_result · 2025-05-13Clinical Trial Update: Feasibility Trial of Tele-IPT and Tele-Pharmacotherapy for Patients With Depression and Non-Metastatic Breast Cancer [Phase 3]
A Phase 3 feasibility trial of Tele-IPT and tele-pharmacotherapy for patients with Major Depressive Disorder and non-metastatic breast cance…
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CLINICAL_TRIALS trial_result · 2025-05-11Clinical Trial Update: Affect Treatment for Depression and Anxiety (TAD Pilot) [NA]
The TAD Pilot trial (NCT06488859) investigating affect treatment for depression and anxiety has completed.
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CLINICAL_TRIALS trial_result · 2025-05-11Clinical Trial Update: A Randomized Control Trial Treating Depression With Yoga and Coherent Breathing Versus Walking in Veterans [NA]
A randomized trial comparing yoga with coherent breathing versus walking in U.S. veterans with major depressive disorder and post-traumatic …
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CLINICAL_TRIALS trial_result · 2025-05-11Clinical Trial Update: Project MATLINK: Development and Evaluation of a Screening, Brief Intervention, & Referral to Treatment (SBIRT) Program for Opioid Dependent Prisoners and Probationers Transitioning to the Community [NA]
This completed clinical trial evaluated a Screening, Brief Intervention, and Referral to Treatment (SBIRT) program for opioid-dependent pris…
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CLINICAL_TRIALS trial_result · 2025-05-09Clinical Trial Update: GW117 ODT （Orally Disintegrating Tablets） Safety and Pharmacokinetics Study in Healthy Subjects [Phase 1]
Phase 1 safety and pharmacokinetics study of GW117 orally disintegrating tablets conducted in healthy subjects; Major depressive disorder is…
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CLINICAL_TRIALS trial_result · 2025-05-09Clinical Trial Update: Preconception and Pregnancy Obesity Treatment and Prevention Among Women With a History of Depression [NA]
A clinical trial evaluating preconception and pregnancy obesity treatment and prevention in women with a history of depression has completed…
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CLINICAL_TRIALS trial_result · 2025-05-09Clinical Trial Update: Scaling Well-Being for Educators During COVID-19 [NA]
A completed clinical trial from the University of Wisconsin, Madison investigated scaling well-being interventions for educators during COVI…
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CLINICAL_TRIALS trial_result · 2025-05-09Clinical Trial Update: Deep Phenotyping for Clinical Inferring Response in Treatment Resistant Depression
A clinical trial update from Max-Planck-Institute of Psychiatry describes deep phenotyping to infer treatment response in treatment-resistan…
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CLINICAL_TRIALS trial_result · 2025-05-08Clinical Trial Update: Elucidating the Neurocircuitry of Irritability With High-Field Neuroimaging to Identify Novel Therapeutic Targets [Phase 2]
A completed Phase 2 study that uses high-field neuroimaging to map the neural circuits linked to irritability in people with major depressiv…
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CLINICAL_TRIALS trial_result · 2025-05-08Clinical Trial Update: Cross-Cultural Differences in the Network Structure of Social Anxiety and Body Dysmorphic Symptoms
A completed clinical trial update examining cross-cultural differences in the network structure of social anxiety and body dysmorphic sympto…
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CLINICAL_TRIALS trial_result · 2025-05-06Clinical Trial Update: Is Betwixt App Effective and Acceptable? [NA]
The document reports the completion of a clinical trial conducted by the University of Nottingham evaluating the Betwixt app for major depre…
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CLINICAL_TRIALS trial_result · 2025-05-06Clinical Trial Update: Emotion Focused Therapy for Competitive Athletes [NA]
This entry reports the completion of a clinical trial evaluating emotion-focused therapy for depression and anxiety in competitive athletes,…
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CLINICAL_TRIALS trial_result · 2025-05-02Clinical Trial Update: Clinical Trial of Lumateperone as Adjunctive Therapy in the Treatment of Patients With Major Depressive Disorder [Phase 3]
A Phase 3 trial evaluating lumateperone as adjunctive therapy for major depressive disorder has completed and results have been posted.
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CLINICAL_TRIALS trial_result · 2025-05-02Clinical Trial Update: Study of the Safety, Tolerability, Electrophysiological Effects and Efficacy of DMT in Humans [Phase 1]
Phase 1 study assessing safety, tolerability, electrophysiological effects, and preliminary efficacy of N,N-Dimethyltryptamine in adults wit…
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CLINICAL_TRIALS trial_result · 2025-05-02Clinical Trial Update: Behavior, Biology and Well-Being Study [NA]
The University of Wisconsin–Madison sponsored the Behavior, Biology and Well-Being Study completed with results posted in May 2025. It focus…
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CLINICAL_TRIALS trial_result · 2025-04-30Clinical Trial Update: Multiphase Optimization Trial of Incentives for Veterans to Encourage Walking [NA]
A VA-sponsored multiphase optimization trial evaluated incentives to encourage walking among veterans to reduce sedentary behavior; the stud…
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CLINICAL_TRIALS trial_result · 2025-04-29Clinical Trial Update: A Study of the Efficacy of Intravenous Esketamine in Adult Patients With Treatment-Resistant Depression [Phase 2]
This Phase 2 trial update reports on the efficacy of intravenous esketamine in adults with treatment-resistant major depressive disorder. Th…
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CLINICAL_TRIALS trial_result · 2025-04-29Clinical Trial Update: A Safety and Efficacy Study of JNJ26489112 in Patients With Treatment-Resistant Major Depressive Disorder [Phase 2]
A Phase 2 safety and efficacy study of JNJ26489112 in treatment-resistant major depressive disorder was terminated. No results are provided …
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CLINICAL_TRIALS trial_result · 2025-04-27Clinical Trial Update: A Study of Seltorexant as Adjunctive Therapy to Antidepressants in Adult and Elderly Participants With Major Depressive Disorder With Insomnia Symptoms Who Have Responded Inadequately to Antidepressant and Long-term Safety Extension Treatment With Seltorexant [Phase 3]
Phase 3 study of Seltorexant as adjunctive therapy to antidepressants for adults and elderly with major depressive disorder with insomnia sy…