Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-06-23Clinical Trial Results: Transdiagnostic Brain-Behavior Profiling to Enhance Cognitive Behavioral Therapy Response [NA]
Clinical trial results on transdiagnostic brain-behavior profiling to enhance CBT response, completed with results posted in 2026.
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CLINICAL_TRIALS trial_result · 2026-06-17Clinical Trial Results: Neuromodulation for Comorbid Hoarding Disorder and Depression [NA]
Clinical trial results on neuromodulation for comorbid hoarding disorder and depression have been completed with results posted.
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CLINICAL_TRIALS trial_result · 2026-06-17Clinical Trial Results: Modulating Repetitive Negative Thinking Related Brain Networks in Young Adults With Depression [NA]
Clinical trial results on modulating repetitive negative thinking related brain networks in young adults with depression; study TERMINATED w…
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CLINICAL_TRIALS trial_result · 2026-06-09Clinical Trial Update: Study to Assess the Safety and Effectiveness of NMRA-335140-501 [Phase 3]
Phase 3 clinical trial update for NMRA-335140-501 assessing safety and effectiveness in Major Depressive Disorder.
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CLINICAL_TRIALS trial_result · 2026-06-08Clinical Trial Results: A Study of Aticaprant Plus an Antidepressant to Prevent Return of Depression Symptoms in Participants With Major Depressive Disorder Who Experience a Loss of Interest and Pleasure [Phase 3]
Phase 3 trial evaluating aticaprant plus antidepressant to prevent return of depressive symptoms in adults with Major Depressive Disorder an…
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CLINICAL_TRIALS trial_result · 2026-06-05Clinical Trial Results: Feasibility & Acceptability of a Virtual Sister Circle Intervention for Black Women With Depressive Symptoms [NA]
A completed clinical trial evaluating the feasibility and acceptability of a virtual sister circle intervention for Black women with depress…
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CLINICAL_TRIALS trial_result · 2026-04-29Clinical Trial Results: Cognitive Fitness for Depression in Older Adults [NA]
Completed clinical trial results for a cognitive fitness intervention targeting depression in older adults; results posted.
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CLINICAL_TRIALS trial_result · 2026-04-29Clinical Trial Results: The Effects of Videogames on Depression Symptoms and Brain Dynamics [NA]
Completed clinical trial assessing the effects of videogames on depression symptoms and brain dynamics in adults with Major Depressive Disor…
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CLINICAL_TRIALS trial_result · 2026-04-28Clinical Trial Update: Pramipexole for Anhedonic Depression [Phase 3]
Phase 3 trial update for pramipexole in anhedonic depression has completed enrollment and status is completed.
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CLINICAL_TRIALS trial_result · 2026-04-28Clinical Trial Update: Long-term Efficacy of Pramipexole in Anhedonic Depression [Phase 3]
Phase 3 trial assessing long-term efficacy of pramipexole in anhedonic depression has completed.
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CLINICAL_TRIALS trial_result · 2026-04-28Clinical Trial Results: Decision Making Tool for Firearm Storage [NA]
The study report for a decision-making tool on firearm storage in adults with mild dementia and depression has been terminated, with results…
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CLINICAL_TRIALS trial_result · 2026-04-27Clinical Trial Update: Comparing Acupuncture With Medication to Reduce Anxiety and Depression in China [Phase 4]
A Phase 4 clinical trial comparing acupuncture with medication to reduce anxiety and depression in China.
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CLINICAL_TRIALS trial_result · 2026-04-27Clinical Trial Update: Neuronavigation Guided iTBS With Personalized Target for Depression [Phase 2]
Phase 2 clinical trial update evaluating neuronavigation-guided intermittent theta-burst stimulation with personalized target for depression…
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: The Effect of Celecoxib on Neuroinflammation in MDD [Phase 4]
A Phase 4 clinical trial evaluating celecoxib for reducing neuroinflammation in patients with major depressive disorder has completed.
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: Sedation and Guided Education for Depression Study [NA]
Clinical trial update for a Sedation and Guided Education for Depression study focused on Major Depressive Disorder; the study status is NOT…
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: A Study of SEP-380135 in Adults With Schizophrenia or Major Depressive Episode [Phase 1]
Phase 1 clinical trial update shows the SEP-380135 study in adults with schizophrenia or major depressive episode has completed. The trial s…
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: Online Self-healing Program [NA]
Clinical trial update for an online self-healing program addressing mild to moderate depressive symptoms; the study is not yet recruiting.
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CLINICAL_TRIALS trial_result · 2026-04-23Clinical Trial Update: Defining and Treating Depression-related Asthma [EARLY_Phase 1]
An early-phase clinical trial update evaluating the definition and treatment of depression-related asthma. Results from the Phase 1 study ha…
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CLINICAL_TRIALS trial_result · 2026-04-23Clinical Trial Update: Neuroimaging Study for Decoding Emotional States and Identifying Neural Circuits to Disengage From Negative Thinking
This completed study from the Laureate Institute for Brain Research used neuroimaging to decode emotional states and identify neural circuit…
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CLINICAL_TRIALS trial_result · 2026-04-23Clinical Trial Update: Effect of Individualized Precise TMS on Emotional Blunting in Depression and Its Brain Imaging Mechanism [NA]
A completed clinical trial evaluates whether individualized precise transcranial magnetic stimulation reduces emotional blunting in depressi…
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CLINICAL_TRIALS trial_result · 2026-04-23Clinical Trial Update: Computerized Cognitive Behavioral Therapy-Depression (cCBT-D) for Caregivers of Veterans [Phase 2]
Phase 2 clinical trial update for Computerized Cognitive Behavioral Therapy for Depression tailored to caregivers of veterans; the study is …
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CLINICAL_TRIALS trial_result · 2026-04-23Clinical Trial Update: Clinical Study of Compound Ciwujia Granules in the Treatment of Depression [Phase 4]
The document reports a Phase 4 clinical study of Compound Ciwujia Granules for depression, sponsored by Shanghai Mental Health Center; the t…
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CLINICAL_TRIALS trial_result · 2026-04-22Clinical Trial Update: A Study of Psilocybin for Major Depressive Disorder (MDD) [Phase 2]
Phase 2 trial of psilocybin for major depressive disorder has completed and results have been posted.
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CLINICAL_TRIALS trial_result · 2026-04-22Clinical Trial Update: Using a Mentoring Afterschool Program to Improve Adolescent Mental Health and Physical Activity: A Pilot Study [NA]
This update reports the completion of a pilot clinical trial evaluating a mentoring afterschool program to improve depressive symptoms and p…
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CLINICAL_TRIALS trial_result · 2026-04-22Clinical Trial Update: Development and Evaluation of an e-Mental Health Program for Depressive Symptoms [NA]
Completed clinical trial evaluating an electronic mental health program for depressive symptoms.