Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-09-12Clinical Trial Update: Vegetarian Diet and Chronic Degenerative Diseases
Completed clinical trial evaluating the impact of a vegetarian diet on dementia, depression, and other chronic diseases.
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CLINICAL_TRIALS trial_result · 2025-09-12Clinical Trial Update: Cultural Arts Programme for Older Chinese [NA]
This clinical trial update notes completion of a cultural arts programme for older Chinese adults aimed at addressing depressive symptoms an…
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CLINICAL_TRIALS trial_result · 2025-09-11Clinical Trial Update: Transcranial Direct Current Stimulation Treatment for Warriors Experiencing Chronic Pain [NA]
A completed clinical trial evaluated transcranial direct current stimulation for veterans with chronic pain, including co-occurring PTSD and…
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CLINICAL_TRIALS trial_result · 2025-09-11Clinical Trial Update: Demonstration Study of the Effect of the Transcranial Direct Current Stimulation (tDCS) on Depressed Patients [NA]
Completed clinical trial from Yonsei University evaluating transcranial direct current stimulation for depression; results were posted on 20…
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CLINICAL_TRIALS trial_result · 2025-09-11Clinical Trial Update: Smart Light Therapy Glasses for Sleep and Mental Wellness [NA]
A completed clinical trial from the University of Waterloo evaluated smart light therapy glasses for improving depressive symptoms and sleep…
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CLINICAL_TRIALS trial_result · 2025-09-09Clinical Trial Update: JoyPop Mobile Mental Health App With Post-Secondary Students [NA]
A completed clinical trial evaluating the JoyPop mobile mental health app for post-secondary students focusing on emotion regulation and dep…
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CLINICAL_TRIALS trial_result · 2025-09-08Clinical Trial Update: Phase 2b Study of ALTO-100 in MDD [Phase 2]
Alto Neuroscience's Phase 2b trial of ALTO-100 for Major Depressive Disorder has completed.
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CLINICAL_TRIALS trial_result · 2025-09-08Clinical Trial Update: Neurofeedback to Treat Depression [NA]
A completed clinical trial evaluating neurofeedback as a treatment for major depressive disorder.
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CLINICAL_TRIALS trial_result · 2025-09-08Clinical Trial Update: Youth to Text or Telehealth for Engagement in HIV Care [NA]
A completed clinical trial evaluating whether text-based or telehealth interventions improve engagement in HIV care among youth, including p…
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CLINICAL_TRIALS trial_result · 2025-09-08Clinical Trial Update: SMART Trial to Predict Anhedonia Response to Antidepressant Treatment [Phase 4]
Phase 4 SMART trial to predict anhedonia response to antidepressant treatment in Major Depressive Disorder has completed.
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CLINICAL_TRIALS trial_result · 2025-09-05Clinical Trial Update: Esketamine vs ECT for Acute Suicidality [NA]
A completed clinical trial comparing esketamine with electroconvulsive therapy for acute suicidality in mood disorders has finished.
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CLINICAL_TRIALS trial_result · 2025-09-05Clinical Trial Update: Low-dose Ketamine Infusion Among Adolescents With Treatment-resistant Depression [Phase 4]
A Phase 4 trial evaluated low-dose ketamine infusions in adolescents with treatment-resistant depression and major depressive disorder. The …
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CLINICAL_TRIALS trial_result · 2025-09-05Clinical Trial Update: PRISM Neurofeedback Training for MDD Anhedonic Patients [NA]
The clinical trial evaluating PRISM neurofeedback training for patients with major depressive disorder and anhedonia has completed; sponsor …
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CLINICAL_TRIALS trial_result · 2025-09-05Clinical Trial Update: Adaptation and Evaluation of the KEEP Model [NA]
The KEEP Model study has completed its adaptation and evaluation for depression, anxiety, and post-traumatic stress disorder.
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CLINICAL_TRIALS trial_result · 2025-09-04Clinical Trial Update: Depression and Facial Identity Recognition Abilities in Patients With Multiple Sclerosis
This completed clinical trial studied depression and facial identity recognition abilities in patients with multiple sclerosis.
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CLINICAL_TRIALS trial_result · 2025-09-04Clinical Trial Update: Feasibility of a Culturally Adapted Emotional-Behavioral Prevention Program for American Indian Children [NA]
The trial evaluates the feasibility of a culturally adapted emotional-behavioral prevention program for American Indian children, focusing o…
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CLINICAL_TRIALS trial_result · 2025-09-03Clinical Trial Update: Electroencephalographic Study of the Mechanisms of Inhibition of Emotional Memories in Young Healthy Subjects [NA]
A completed EEG study investigating neural mechanisms of inhibiting emotional memories in young healthy subjects, with related conditions in…
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CLINICAL_TRIALS trial_result · 2025-09-02Clinical Trial Update: Effect of Psilocybin Only and Psilocybin Assisted Cognitive Behavioral Therapy in the Management of Major Depressive Disorder and Associated Metabolic, Immune, Inflammatory, Neuroplasticity and Electrical Activity Markers [Phase 2]
Phase 2 clinical trial evaluating psilocybin alone and psilocybin-assisted cognitive behavioral therapy for major depressive disorder; the s…
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CLINICAL_TRIALS trial_result · 2025-09-02Clinical Trial Update: Beta-arrestins and Response to Venlafaxine in Major Depressive Disorder (MDD) (DEPARRESTCLIN) [Phase 4]
Phase 4 clinical trial updates beta-arrestins’ relationship with venlafaxine response in adults with major depressive disorder. The study (D…
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CLINICAL_TRIALS trial_result · 2025-08-29Clinical Trial Update: Treatment of Depression and/or Anxiety - the Tree Theme Method® (TTM) as an Intervention [NA]
The trial evaluating the Tree Theme Method as an intervention for depression and/or anxiety has completed; no results are provided in the sn…
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CLINICAL_TRIALS trial_result · 2025-08-26Clinical Trial Update: Reducing Adolescent Suicide Risk: Safety, Efficacy, and Connectome Phenotypes of Intravenous Ketamine [Phase 2]
Phase 2 trial evaluating intravenous ketamine for reducing suicide risk in adolescents was terminated, with results posted.
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CLINICAL_TRIALS trial_result · 2025-08-26Clinical Trial Update: Efficacy of Metacognitive Training in Older Adults With Depression [NA]
Clinical trial investigating the efficacy of metacognitive training in older adults with depression has completed.
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CLINICAL_TRIALS trial_result · 2025-08-22Clinical Trial Update: Berries, Bugs, and the Blues [NA]
This entry reports the completion of a clinical trial assessing depressive symptoms, with results posted on 2025-08-22.
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CLINICAL_TRIALS trial_result · 2025-08-22Clinical Trial Update: Cognitive Behavioural Therapy for Complicated Grief Reactions in Old Age [NA]
The University of Aarhus completed a clinical trial evaluating Cognitive Behavioural Therapy for complicated grief reactions in older adults…
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CLINICAL_TRIALS trial_result · 2025-08-22Clinical Trial Update: Intradermal Acupuncture Based on Changes in Biological Specificity of Acupoints for Major Depressive Disorder [NA]
This clinical trial update indicates that a study assessing intradermal acupuncture guided by acupoint biology for major depressive disorder…