Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2012-07-04Clinical Trial Update: Oral Tyramine Pressor Response Study of CX157 Tablets in Healthy Male Volunteers [Phase 1]
This clinical trial update reports the completion of a Phase 1 study evaluating the oral tyramine pressor response of CX157 tablets in healt…
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CLINICAL_TRIALS trial_result · 2012-06-29Clinical Trial Update: The Effects of Eszopiclone and Lexapro on Prefrontal Glutamate and GABA in Depression With Anxiety and Insomnia [Phase 4]
A Phase 4 trial evaluated the effects of eszopiclone and escitalopram (Lexapro) on prefrontal glutamate and GABA in adults with depression w…
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CLINICAL_TRIALS trial_result · 2012-06-27Clinical Trial Update: Relapse Prevention Study Of Desvenlafaxine Succinate Sustained Release In Outpatients With Major Depressive Disorder [Phase 3]
Phase 3 relapse-prevention trial of desvenlafaxine sustained release in outpatients with major depressive disorder has completed with result…
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CLINICAL_TRIALS trial_result · 2012-06-27Clinical Trial Update: A Study of CX157 (TriRima) for the Treatment of Depression [Phase 2]
This Phase 2 trial of CX157 (TriRima) for Major Depressive Disorder has completed and its results have been posted.
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CLINICAL_TRIALS trial_result · 2012-06-27Clinical Trial Update: Sequence Towards Remission in Depression [Phase 4]
This clinical trial update concerns a Phase 4 study titled 'Sequence Towards Remission in Depression,' with the current status not disclosed…
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CLINICAL_TRIALS trial_result · 2012-06-25Clinical Trial Update: Building Recovery By Improving Goals, Habits, and Thoughts [NA]
A completed clinical trial sponsored by RAND addressing Depression and Substance Use; results posted in 2012.
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CLINICAL_TRIALS trial_result · 2012-06-22Clinical Trial Update: Randomised Controlled Trial of Electroconvulsive Therapy (ECT) in Relapse Prevention of Depression [Phase 4]
A Phase 4 randomized trial evaluating electroconvulsive therapy for relapse prevention in major depressive disorder has completed.
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CLINICAL_TRIALS trial_result · 2012-06-20Clinical Trial Update: Bupropion For Reducing High-Risk Behaviors in Depressed Men Who Have Sex With Men (MSM) [Phase 1]
Phase 1 clinical trial update evaluating whether bupropion can reduce high-risk behaviors in depressed men who have sex with men (MSM). The …
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CLINICAL_TRIALS trial_result · 2012-06-19Clinical Trial Update: Quetiapine Extended Release Depression Symptoms [Phase 3]
A Phase 3 trial evaluating quetiapine extended-release for schizophrenia and depressive symptoms has completed and results have been posted.
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CLINICAL_TRIALS trial_result · 2012-06-14Clinical Trial Update: Deep Brain Stimulation for Treatment-Refractory Major Depression [Phase 1]
Phase 1 clinical trial evaluating deep brain stimulation for treatment-refractory major depression, conducted at University Hospital Bonn; t…
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CLINICAL_TRIALS trial_result · 2012-06-11Clinical Trial Update: Disseminating Evidence-based Mood Disorder Chronic Care Models [NA]
The University of Michigan-sponsored trial has completed and focused on disseminating evidence-based chronic care models for mood disorders,…
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CLINICAL_TRIALS trial_result · 2012-06-04Clinical Trial Update: A Local Register Study For Major Depression Of Paroxetine Controlled Release [Phase 3]
A Phase 3 local register study evaluating paroxetine controlled release for major depressive disorder has completed.
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CLINICAL_TRIALS trial_result · 2012-06-01Clinical Trial Update: Feasibility of Depression Care Management by E-mail [NA]
A completed Kaiser Permanente trial evaluating the feasibility of managing depression care via email, with results posted in 2012.
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CLINICAL_TRIALS trial_result · 2012-05-31Clinical Trial Update: A Trial of Inflammatory Markers, Depressive Symptoms, and Heart Disease [Phase 1]
Phase 1 clinical trial investigating the relationship between inflammatory markers, depressive symptoms, and heart disease, which has been t…
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CLINICAL_TRIALS trial_result · 2012-05-25Clinical Trial Update: Evaluation of the Potential Effects of SSR149415 on the Hypothalamic-pituitary-adrenal Axis in Outpatients With Major Depressive Disorder [Phase 2]
Phase 2 clinical trial evaluating the potential effects of SSR149415 on the hypothalamic-pituitary-adrenal axis in outpatients with major de…
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CLINICAL_TRIALS trial_result · 2012-05-25Clinical Trial Update: An Intervention Study to Increase Physical Activity and Maternal Well-being During Pregnancy [EARLY_Phase 1]
An early-phase trial evaluating an intervention to increase physical activity and maternal well-being during pregnancy has completed.
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CLINICAL_TRIALS trial_result · 2012-05-23Clinical Trial Update: Comparing Quetiapine XR Monotherapy and Augmentation With Lithium Augmentation in TRD Patients [Phase 3]
Phase 3 clinical trial comparing quetiapine XR as monotherapy versus augmentation with lithium in treatment-resistant depression. Results we…
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CLINICAL_TRIALS trial_result · 2012-05-21Clinical Trial Update: Phase IV Trial With Pramipexole to Evaluate Safety and Efficacy in Patients With RLS Associated With Mood Disturbances [Phase 4]
This Phase IV trial update reports the completion of a study evaluating the safety and efficacy of pramipexole for restless legs syndrome as…
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CLINICAL_TRIALS trial_result · 2012-05-11Clinical Trial Update: Acceleration and Relapse Prevention With Triiodothyronine (T3) as an Adjunct to Electroconvulsive Therapy (ECT)
A completed trial assessed whether adding tri-iodothyronine (T3) to electroconvulsive therapy accelerates antidepressant response. The study…
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CLINICAL_TRIALS trial_result · 2012-05-09Clinical Trial Update: Safety and Efficacy Study of Vilazodone and Discovering Genetic Markers Associated With Response in Patients With Major Depressive Disorder [Phase 2]
A Phase 2 safety and efficacy study of vilazodone in patients with Major depressive disorder, including exploration of genetic markers assoc…
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CLINICAL_TRIALS trial_result · 2012-05-09Clinical Trial Update: Pioglitazone as an Adjunct for Moderate to Severe Depressive Disorder [Phase 2, Phase 3]
Pioglitazone is being studied as an adjunctive treatment for moderate to severe major depressive disorder in Phase 2 and Phase 3 trials. The…
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CLINICAL_TRIALS trial_result · 2012-05-09Clinical Trial Update: The WORKER Study: Escitalopram and Telephone-based Cognitive Behaviour Therapy (CBT) for Depressed Working People [NA]
A completed clinical trial evaluating escitalopram in combination with telephone-based CBT for depressed working adults.
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CLINICAL_TRIALS trial_result · 2012-05-07Clinical Trial Update: Study Evaluating Desvenlafaxine Succinate Sustained Release (DVS SR) Versus Placebo in Peri- and Postmenopausal Women [Phase 3]
Phase 3 study evaluating Desvenlafaxine succinate sustained release (DVS SR) versus placebo in peri- and postmenopausal women with depressio…
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CLINICAL_TRIALS trial_result · 2012-05-07Clinical Trial Update: Vocal Acoustic Biomarkers in Depression
Completed clinical trial evaluating vocal acoustic biomarkers in major depressive disorder.
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CLINICAL_TRIALS trial_result · 2012-05-04Clinical Trial Update: Tailored Internet-delivered Cognitive Behaviour Therapy in Primary Care [NA]
This clinical trial update reports on a tailored internet-delivered cognitive behaviour therapy program tested in primary care for depressio…