Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-12-18Clinical Trial Update: rTMS in Alleviating Pain and Co-Morbid Symptoms in Gulf War Veterans Illness (GWVI) [NA]
A completed clinical trial evaluating repetitive transcranial magnetic stimulation (rTMS) for pain and co-morbid symptoms in Gulf War Illnes…
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CLINICAL_TRIALS trial_result · 2025-12-16Clinical Trial Update: A Clinical Study to Evaluate of Single and Multiple Oral Doses of GM-1020 in Patients With MDD [Phase 2]
Phase 2 trial of GM-1020 for major depressive disorder has completed. The study evaluated single and multiple oral doses.
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CLINICAL_TRIALS trial_result · 2025-12-16Clinical Trial Update: Exploring the Effects of Corticosteroids on the Human Hippocampus [Phase 4]
Phase 4 clinical trial evaluating the effects of hydrocortisone on the hippocampus in depression; results have been completed and posted.
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CLINICAL_TRIALS trial_result · 2025-12-16Clinical Trial Update: Evaluation of the Initial Prescription of Ketamine and Milnacipran in Depression in Patients With a Progressive Disease [Phase 2, Phase 3]
This report updates on a completed Phase 2/3 clinical trial evaluating the initial prescription of ketamine and milnacipran for depression i…
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CLINICAL_TRIALS trial_result · 2025-12-16Clinical Trial Update: OMT as an Adjunctive Treatment in MDD [NA]
This entry reports the completion of a clinical trial evaluating OMT as an adjunctive treatment for Major Depressive Disorder.
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CLINICAL_TRIALS trial_result · 2025-12-15Clinical Trial Update: ABSORB (Amount of Blueberries So Older Adults Reap Benefits) [NA]
A completed clinical trial evaluating whether blueberry consumption benefits depressive symptoms in older adults; results have been posted.
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CLINICAL_TRIALS trial_result · 2025-12-15Clinical Trial Update: Cognitive Behavioral Immersion: A Randomized Control Trial of Peer-Based Coaching in the Metaverse [NA]
A completed randomized trial assessing a peer-based coaching intervention delivered in a metaverse setting for depression and anxiety.
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CLINICAL_TRIALS trial_result · 2025-12-12Clinical Trial Update: Pramipexole to Target "Anhedonic Depression" [Phase 2]
Phase 2 trial of pramipexole for anhedonic depression has been completed, evaluating its effects in bipolar and unipolar depression. Results…
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CLINICAL_TRIALS trial_result · 2025-12-12Clinical Trial Update: Psilocybin-assisted CBT for Depression [Phase 1]
Phase 1 study evaluating psilocybin-assisted cognitive-behavioral therapy for Major Depressive Disorder has been completed.
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CLINICAL_TRIALS trial_result · 2025-12-12Clinical Trial Update: Comparison of Propofol and Ketofol as Induction Agents for Electroconvulsive Therapy [NA]
A completed clinical trial comparing propofol and ketofol as induction agents for electroconvulsive therapy in adults with major depressive …
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CLINICAL_TRIALS trial_result · 2025-12-12Clinical Trial Update: The Effects of Exercise and Music Combination on Drug Cravings, Depression and Self-Efficacy Among Drug Addicts [NA]
This completed clinical trial evaluated whether a combination of exercise and music could reduce drug cravings and depression and improve se…
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CLINICAL_TRIALS trial_result · 2025-12-11Clinical Trial Update: Brain Markers of Depression Vulnerability: the Case of Prefrontal Haemodynamic Response
The clinical trial investigating brain markers of depression vulnerability using prefrontal haemodynamic response has completed.
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CLINICAL_TRIALS trial_result · 2025-12-11Clinical Trial Update: Aging and Reward System Response to Inflammation and Anxiety Study [Phase 1]
Phase 1 clinical trial from UCLA evaluating how aging and inflammation interact with anxiety to affect reward system response; the study has…
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CLINICAL_TRIALS trial_result · 2025-12-10Clinical Trial Update: Effectiveness of Traditional Chinese Metacognitive Training (MCT) in Patients With Schizophrenia, Depression, or Bipolar Disorder Attending a Psychiatric Day Hospital in Taiwan [NA]
A completed clinical trial in Taiwan evaluated the effectiveness of Traditional Chinese Metacognitive Training for schizophrenia, major depr…
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CLINICAL_TRIALS trial_result · 2025-12-10Clinical Trial Update: Research on Three-level Prevention and Intervention for Elderly Depression in Urban Community [NA]
A clinical trial evaluating a three-level prevention and intervention approach for depression in elderly urban residents has completed.
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CLINICAL_TRIALS trial_result · 2025-12-10Clinical Trial Update: Mood Lifters for Undergraduates [NA]
A completed University of Michigan clinical trial studying mood-related interventions for undergraduates with depression and anxiety.
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CLINICAL_TRIALS trial_result · 2025-12-09Clinical Trial Update: Personalized Integrated Chronotherapy for Perinatal Depression [NA]
Rhode Island Hospital-sponsored trial investigating personalized integrated chronotherapy for perinatal depression has completed and posted …
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CLINICAL_TRIALS trial_result · 2025-12-09Clinical Trial Update: Multimodal Intervention for Older Adults After an Earthquake [NA]
A completed clinical trial evaluated a multimodal intervention for frailty, PTSD, depression, malnutrition, and falls in older adults after …
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CLINICAL_TRIALS trial_result · 2025-12-08Clinical Trial Update: Ketamine for the Treatment of Depression in Parkinson's Disease [Phase 2]
Phase 2 clinical trial of ketamine for depression in Parkinson's disease has completed.
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CLINICAL_TRIALS trial_result · 2025-12-08Clinical Trial Update: BIOMARKERS FOR DRUG SELECTION IN DEPRESSION
A clinical trial investigating biomarkers to guide drug selection for major depressive disorder has completed, sponsored by Neomente SAS.
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CLINICAL_TRIALS trial_result · 2025-12-04Clinical Trial Update: D-Cycloserine Augmentation of Intermittent Theta Burst Stimulation (iTBS) in Depression (COGENT) [Phase 2]
This document provides an update on a Phase 2 trial evaluating D-Cycloserine augmentation of intermittent theta burst stimulation (iTBS) for…
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CLINICAL_TRIALS trial_result · 2025-12-04Clinical Trial Update: College Student Stress: Transitions Over Time [NA]
A completed clinical trial evaluating college student stress and depressive symptoms has posted results (NCT06583096).
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CLINICAL_TRIALS trial_result · 2025-12-04Clinical Trial Update: Post-traumatic Stress, Signs of Depression and Burnout Syndrome Among Nursing Home Staff in Occitanie During the COVID-19 Pandemic
A completed clinical study evaluating post-traumatic stress, anxiety, depressive symptoms, and burnout among nursing home staff in Occitanie…
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CLINICAL_TRIALS trial_result · 2025-12-04Clinical Trial Update: Enhancing Depression Literacy and Reducing Stigma in Adolescents Through Social Media [NA]
A clinical trial at Ludwig-Maximilians-Universität München evaluating a social media–based intervention to enhance depression literacy and r…
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CLINICAL_TRIALS trial_result · 2025-12-02Clinical Trial Update: SMART-DAPPER: Leveraging the Depression And Primary-care Partnership for Effectiveness-implementation Research Project [NA]
The SMART-DAPPER study on depression and posttraumatic stress disorder in primary care has completed, with results posted on 2025-12-02.