Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2015-10-14Clinical Trial Update: Major Depressive Disorder With Mixed Features - Extension [Phase 3]
Extension of a Phase 3 trial in major depressive disorder with mixed features; results were posted in 2015.
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CLINICAL_TRIALS trial_result · 2015-10-12Clinical Trial Update: Efficacy and Safety of Fixed Doses of BMS 820836 in the Treatment of Patients With Treatment Resistant Major Depression [Phase 2]
This Phase 2 trial evaluated the efficacy and safety of fixed doses of BMS 820836 in patients with treatment-resistant major depression. The…
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CLINICAL_TRIALS trial_result · 2015-10-12Clinical Trial Update: Efficacy and Safety of Flexibly Dosed BMS-820836 in the Treatment of Patients With Treatment Resistant Major Depression [Phase 2]
A Phase 2 trial evaluating the efficacy and safety of flexibly dosed BMS-820836 in patients with treatment-resistant major depressive disord…
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CLINICAL_TRIALS trial_result · 2015-10-12Clinical Trial Update: Cognitive and Drug Therapy for Drug-Resistant Depression [NA]
A completed clinical trial evaluating cognitive and pharmacologic therapies for treatment-resistant depression.
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CLINICAL_TRIALS trial_result · 2015-10-12Clinical Trial Update: Long-term Safety and Tolerability of BMS-820836 in the Treatment of Patients With Treatment Resistant Major Depression [Phase 2]
Phase 2 long-term safety and tolerability study of BMS-820836 in treatment-resistant major depression was terminated; the update provides sa…
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CLINICAL_TRIALS trial_result · 2015-10-09Clinical Trial Update: Major Depressive Disorder (MDD) With Mixed Features - Flexible Dose [Phase 3]
A Phase 3 trial evaluating a flexible-dose regimen for Major Depressive Disorder with mixed features has completed and results were posted i…
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CLINICAL_TRIALS trial_result · 2015-10-08Clinical Trial Update: Brexpiprazole as Adjunctive Therapy With Major Depressive Disorder and an Inadequate Response to Previous Adjunctive Therapy [Phase 3]
Phase 3 trial results for brexpiprazole as adjunctive therapy in adults with major depressive disorder with inadequate response to prior adj…
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CLINICAL_TRIALS trial_result · 2015-10-06Clinical Trial Update: Relapse Prevention for Bipolar Type-II Disorder [Phase 4]
Phase 4 relapse-prevention clinical trial in bipolar disorder (including Bipolar Type II) with co-occurring depression has completed.
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CLINICAL_TRIALS trial_result · 2015-10-06Clinical Trial Update: Sertraline for Alcohol Dependence and Depression [Phase 4]
This document reports the completion of a Phase 4 clinical trial evaluating sertraline for alcohol use disorder and depression. The study wa…
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CLINICAL_TRIALS trial_result · 2015-10-06Clinical Trial Update: Multicenter Comparative Study of the Activity of the Medial Prefrontal Cortex in Vulnerability to Depression
A multicenter study assessing medial prefrontal cortex activity as a predictor of vulnerability to major depressive disorder; the trial stat…
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CLINICAL_TRIALS trial_result · 2015-10-05Clinical Trial Update: Comparative Trial of Antidepressant Treatment Models in HIV Care in Uganda [Phase 4]
Phase 4 trial in Uganda evaluating antidepressant treatment models for people with HIV has completed.
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CLINICAL_TRIALS trial_result · 2015-10-02Clinical Trial Update: Feasibility and Tolerability of Adjunct Chronotherapy in Depressed Inpatients [NA]
ClinicalTrials.gov update on a feasibility and tolerability study of adjunct chronotherapy (light therapy) in hospitalized patients with maj…
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CLINICAL_TRIALS trial_result · 2015-10-01Clinical Trial Update: Efficacy of Nepeta Menthoides Extract on Anxiety of Patients With Depression: a Double-blind Randomized Controlled Clinical Trial [Phase 2, Phase 3]
A double-blind randomized trial (Phase 2/3) assessed the efficacy of Nepeta menthoides extract for anxiety in patients with depression, with…
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CLINICAL_TRIALS trial_result · 2015-10-01Clinical Trial Update: Antidepressant Plus Asenapine Versus Antidepressant Plus Placebo for Depression [Phase 4]
Phase 4 trial comparing an antidepressant plus asenapine to an antidepressant plus placebo in adults with major depressive disorder without …
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CLINICAL_TRIALS trial_result · 2015-09-17Clinical Trial Update: Improving Depression Outcome by Enhancing Memory for Cognitive Therapy [Phase 2]
This update notes the completion of a Phase 2 trial evaluating whether enhancing memory can improve outcomes of cognitive therapy for major …
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CLINICAL_TRIALS trial_result · 2015-09-17Clinical Trial Update: Trial of Transcranial Direct Current Stimulation (tDCS) for Depression [Phase 2]
A Phase 2 clinical trial evaluating transcranial direct current stimulation (tDCS) for major depressive disorder has completed.
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CLINICAL_TRIALS trial_result · 2015-09-17Clinical Trial Update: Trial of Bilateral tDCS for Depression [Phase 1, Phase 2]
A clinical trial update indicates the Phase 1 and Phase 2 trials of bilateral transcranial direct current stimulation for major depressive d…
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CLINICAL_TRIALS trial_result · 2015-09-17Clinical Trial Update: Brief Behavioral Intervention for Comorbid Migraine and Depression [NA]
Completed clinical trial evaluating a brief behavioral intervention for comorbid migraine and depression; results posted in 2015.
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CLINICAL_TRIALS trial_result · 2015-09-10Clinical Trial Update: Effectiveness of School-Based Cognitive Behavioral Therapy in Preventing Depression in Young Adolescents [Phase 3]
Phase 3 trial evaluating school-based cognitive behavioral therapy shows effectiveness in preventing depression among young adolescents, wit…
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CLINICAL_TRIALS trial_result · 2015-09-02Clinical Trial Update: Effect of Antidepressants on the Treatment for Korean Major Depressive Disorder Patients [Phase 4]
Phase 4 clinical trial in Korea evaluating the effect of antidepressants on treatment outcomes for patients with Major Depressive Disorder; …
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CLINICAL_TRIALS trial_result · 2015-09-01Clinical Trial Update: Kinetics of Fluvoxamine and Digoxin in Subjects With Different MDR1 Genotypes [Phase 1]
Phase 1 pharmacokinetic study evaluating how fluvoxamine and digoxin are affected by different MDR1 genotypes; the study has completed in su…
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CLINICAL_TRIALS trial_result · 2015-08-31Clinical Trial Update: Neurocognitive Enhancement in Major Depressive Disorder [NA]
The clinical trial investigating neurocognitive enhancement in Major Depressive Disorder has completed.
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CLINICAL_TRIALS trial_result · 2015-08-31Clinical Trial Update: Concurrent Treatment for Depressed Parents and DepressedAdolescents [NA]
A completed clinical trial from Brown University studied concurrent treatment for depressed parents and depressed adolescents; results were …
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CLINICAL_TRIALS trial_result · 2015-08-31Clinical Trial Update: Continuation Electroconvulsive Therapy (C-ECT) for Relapse Prevention in Major Depression [Phase 4]
A Phase 4 trial examining continuation electroconvulsive therapy for relapse prevention in major depression has been terminated.
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CLINICAL_TRIALS trial_result · 2015-08-19Clinical Trial Update: Desipramine for Improving Cellular Signaling and Decreasing Symptoms of Major Depression [Phase 4]
This document reports a Phase 4 clinical trial evaluating desipramine for improving cellular signaling and reducing symptoms in major depres…