Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-12-31Clinical Trial Update: ENX-104 MAD Study for Participants With Major Depressive Disorder With Anhedonia (aMDD) [Phase 1]
The document reports the completion of a Phase 1 MAD study of ENX-104 in adults with major depressive disorder with anhedonia (aMDD), sponso…
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CLINICAL_TRIALS trial_result · 2025-12-31Clinical Trial Update: Comorbidity Screening and Referral by Prosthetists [NA]
This completed clinical trial studied comorbidity screening and referral practices by prosthetists. It examined conditions such as limb isch…
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CLINICAL_TRIALS trial_result · 2025-12-30Clinical Trial Update: Microdosing Psychedelics to Improve Mood [Phase 2]
A Phase 2 clinical trial investigating microdosing psychedelics to improve mood in adults with Major Depressive Disorder has completed.
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CLINICAL_TRIALS trial_result · 2025-12-30Clinical Trial Update: Olfactory Training and Emotional State [NA]
This clinical trial update reports the completion of a study evaluating whether olfactory training can improve emotional state in people wit…
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CLINICAL_TRIALS trial_result · 2025-12-30Clinical Trial Update: Examination of Glutamate and mGluR5 in Psychiatric Disorders [NA]
The Yale University–sponsored trial examining glutamate signaling and mGluR5 involvement in major depressive disorder, post-traumatic stress…
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CLINICAL_TRIALS trial_result · 2025-12-30Clinical Trial Update: A Study of Pregnant and Postpartum Women With and Without Mood Disorders
Completed clinical trial NCT03615794 sponsored by Johns Hopkins University studying mood disorders in pregnant and postpartum women.
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CLINICAL_TRIALS trial_result · 2025-12-29Clinical Trial Update: Ayahuasca and Esketamine for Major Depression [Phase 2]
Phase 2 trial evaluating ayahuasca and esketamine for severe major depressive disorder has completed.
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CLINICAL_TRIALS trial_result · 2025-12-26Clinical Trial Update: Dance-movement Therapy in the Treatment of Adolescent Depression [NA]
This clinical trial evaluates dance-movement therapy for adolescent depression. The study is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-12-24Clinical Trial Update: Transcranial Pulse Stimulation for Depression [NA]
The clinical trial evaluating transcranial pulse stimulation for major depressive disorder has completed.
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CLINICAL_TRIALS trial_result · 2025-12-24Clinical Trial Update: Cardiac Markers in Depressed Patients With Coronary Heart Disease - R01HL147862
A completed clinical trial evaluating cardiac markers in patients with both depression and coronary artery disease.
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CLINICAL_TRIALS trial_result · 2025-12-24Clinical Trial Update: Strengthening Families Living With HIV in Kenya [NA]
This is a completed clinical trial in Kenya evaluating a program to support families living with HIV, with a focus on ART adherence and asso…
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CLINICAL_TRIALS trial_result · 2025-12-23Clinical Trial Update: Psilocybin in Co-occuring Major Depressive Disorder and Borderline Personality Disorder [Phase 2]
Phase 2 clinical trial evaluating psilocybin for co-occurring major depressive disorder and borderline personality disorder has completed.
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CLINICAL_TRIALS trial_result · 2025-12-23Clinical Trial Update: Behavioral Activation Teletherapy to Increase Physical Activity [NA]
A completed clinical trial evaluating behavioral activation teletherapy aimed at increasing physical activity in people with depression-rela…
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CLINICAL_TRIALS trial_result · 2025-12-23Clinical Trial Update: BDNF Gene Polymorphism and Antidepressants Treatment [Phase 4]
Phase 4 clinical trial update on whether BDNF gene polymorphism influences treatment with antidepressants in depression; the study has been …
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CLINICAL_TRIALS trial_result · 2025-12-23Clinical Trial Update: Biomarkers of Antidepressant Resistance [NA]
A completed clinical trial investigating biomarkers associated with antidepressant resistance in depression.
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CLINICAL_TRIALS trial_result · 2025-12-23Clinical Trial Update: Stingless Bee Honey Augmentation in Major Depressive Disorders [NA]
A clinical trial investigating stingless bee honey as an adjunct to standard care for major depressive disorder has completed.
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CLINICAL_TRIALS trial_result · 2025-12-22Clinical Trial Update: Effects of Ghrelin Administration on Dopamine and Effort [Phase 1, Phase 2]
A Phase 1/2 clinical trial assessing the effects of ghrelin administration on dopamine signaling and effort-related processes in individuals…
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CLINICAL_TRIALS trial_result · 2025-12-22Clinical Trial Update: Effects of Ghrelin Administration on Motivation [NA]
A completed clinical trial examined whether ghrelin administration affects motivation in individuals with major depressive disorder.
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CLINICAL_TRIALS trial_result · 2025-12-22Clinical Trial Update: Physiologic Monitoring of Antidepressant Response [Phase 4]
Phase 4 clinical trial from UCLA on physiologic monitoring to assess antidepressant response in major depressive disorder has completed.
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CLINICAL_TRIALS trial_result · 2025-12-22Clinical Trial Update: Evaluation of a Home-based Community Health Worker Program in Rural Eastern Cape, South Africa
A completed clinical trial evaluating a home-based community health worker program in rural Eastern Cape, South Africa, assessing outcomes r…
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CLINICAL_TRIALS trial_result · 2025-12-19Clinical Trial Update: Characterizing Inflammatory Profiles and Suicidal Behavior in Adolescents
The University of Texas Southwestern Medical Center completed a clinical trial investigating inflammatory profiles and suicidal behavior in …
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CLINICAL_TRIALS trial_result · 2025-12-19Clinical Trial Update: Qigong Relaxation Exercise [NA]
A clinical trial evaluating a Qigong relaxation exercise for anxiety and depressive symptoms has completed.
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CLINICAL_TRIALS trial_result · 2025-12-19Clinical Trial Update: Neuropsychological Impact of Hospitalization on Intubated, Ventilated and Sedated ICU Patients [NA]
This clinical trial update reports the completion of a study evaluating the neuropsychological impact of ICU hospitalization in patients who…
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CLINICAL_TRIALS trial_result · 2025-12-18Clinical Trial Update: Spanish Intervention for Caregivers of Veterans With Stroke [NA]
Completed clinical trial evaluating a Spanish-language intervention for caregivers of veterans with stroke to address depression, with resul…
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CLINICAL_TRIALS trial_result · 2025-12-18Clinical Trial Update: Depression Screening in Black Churches [NA]
A completed clinical trial sponsored by Columbia University studied depression screening in Black churches. The study status is completed an…