Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Home-Based tDCS Treatment Of Major Depressive Disorder [NA]
An ongoing clinical trial is evaluating home-based transcranial direct current stimulation for major depressive disorder; recruitment is cur…
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Gamma Oscillations as a Prognostic Marker for Ketamine Therapy in Treatment Resistant Depression [Phase 1]
This Phase 1 trial investigates whether gamma oscillations can predict response to ketamine therapy in treatment-resistant depression. The s…
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Mentalizing and Epistemic Trust in Patients With Anxiety and Depression. [NA]
A clinical trial investigating mentalizing and epistemic trust in patients with anxiety disorders and depression is currently recruiting, sp…
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Dynamic Networks in Depression Treatment: Mechanisms of Change in Pharmacological, Psychological and Combined Treatment of Depression [Phase 4]
This is a Phase 4 clinical trial update from Goethe University examining mechanisms of change across pharmacological, psychological, and com…
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Technology-assisted Methods to Advance Suicide Prevention Among Youth in Colombia [NA]
A Brown University-led clinical trial in Colombia is evaluating technology-assisted methods to prevent suicide among youths. The study focus…
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Brain Imaging of Cognition Inn Schizophrenia and Depression
A recruiting clinical trial at The Royal Ottawa Mental Health Centre is studying brain imaging and cognition in individuals with schizophren…
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Co-Designing and Evaluating Additional Mothers and Babies Program Content for Expectant and New Parents of Children With Down Syndrome [NA]
Northwestern University reports a trial update on co-designing and evaluating additional Mothers and Babies program content for expectant an…
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: ICBT (Internet Based Cognitive Behavioral Therapy) for Maternal Depression: Community Implementation in Head Start [NA]
A clinical trial update indicates that an Internet-Based Cognitive Behavioral Therapy program for maternal depression is currently recruitin…
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Sham-Controlled Rapid-Acting Neuromodulation for Depression [NA]
A clinical trial update describes a sham-controlled, rapid-acting neuromodulation study for major depressive disorder. Recruitment has not y…
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CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: Zelquistinel or Placebo for the Reduction of Symptoms of Major Depressive Disorder [Phase 2]
Phase 2 clinical trial comparing Zelquistinel to placebo for reducing symptoms of Major Depressive Disorder; recruitment is ongoing.
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CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: Clinical Assessment of Response in the Treatment of Depression With Daytime Sleepiness Using Solriamfetol [Phase 3]
A Phase 3 clinical trial is ongoing to assess the response to solriamfetol for treating major depressive disorder with excessive daytime sle…
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CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: Effect of Mindfulness-based Psychoeducation in Depression [NA]
A clinical trial is evaluating mindfulness-based psychoeducation, including mindfulness-based stress reduction, for adults with major depres…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: A Clinical Trial of Add-on Oral Slow-release Ketamine Treatment in Major Depression [Phase 2]
This clinical trial update describes an ongoing Phase 2 study evaluating add-on oral slow-release ketamine for major depressive disorder.
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: Neurocognitive Effects of FMT in MDD Patients With and Without IBS [Phase 2, Phase 3]
Clinical trial update on the neurocognitive effects of fecal microbiota transplant in patients with major depressive disorder, with and with…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: rTMS for Depression in Young Adults With Autism [NA]
Clinical trial update indicating ongoing recruitment for a study assessing repetitive transcranial magnetic stimulation (rTMS) to treat depr…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: Adjunctive Bright Light Therapy in Adolescents With Depression and Eveningness [NA]
A clinical trial is evaluating adjunctive bright light therapy for adolescents with unipolar depression and eveningness; the study is curren…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: Get ActivE Study for At-risk Youth [NA]
The Get ActivE study at the University of Pittsburgh is recruiting at-risk youth with anhedonia and depression with suicidal ideation.
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: TCI-Massage Clinical Trial [NA]
The TCI-Massage clinical trial is listed as active but not recruiting, investigating effects on PTSD and comorbid conditions such as chronic…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: A Study to Evaluate the Maintenance Effect of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD) [Phase 3]
This entry describes a Phase 3 clinical trial evaluating NBI-1065845 as an adjunctive maintenance therapy for adults with major depressive d…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: Voice Analysis Technology to Detect and Manage Depression and Anxiety in Cardiac Rehabilitation [NA]
Mayo Clinic is conducting a study using voice analysis technology to detect and manage depression and anxiety among patients undergoing card…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: Cerebellar Stimulation and Cognitive Control [NA]
A clinical trial update notes that a cerebellar stimulation study assessing cognitive control is currently recruiting, with conditions inclu…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: A Randomized Controlled Trial of a VR Social Music-Movement Exergame for Depression and Anxiety in Young Adults [NA]
A randomized controlled trial protocol is described for a VR social music-movement exergame aimed at treating depression and anxiety in youn…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Moving on After Breast Cancer Trial for Depressed Breast Cancer Survivors in Pakistan [NA]
This document is a clinical trial update indicating a study evaluating interventions for major depressive disorder in breast cancer survivor…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Biomarker Research on Ultra-High-Field MRI Combined With Visual Perception Assessment in the Diagnosis and Treatment Outcomes of Severe Mental Disorders
This clinical trial update describes a study evaluating ultra-high-field MRI biomarkers combined with visual perception assessment to improv…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Efficacy and Mechanisms of Escitalopram in Drug-Naïve First-Episode Major Depressive Disorder [NA]
This clinical trial update reports on planned evaluation of escitalopram's efficacy and mechanisms in drug-naïve patients with a first episo…