Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study to Evaluate Sleep Electroencephalogram (EEG) Features (Brain Activity While Sleeping) in Participants With Major Depressive Disorder (MDD)
This ClinicalTrials.gov study is recruiting to evaluate sleep EEG features in adults with major depressive disorder, sponsored by Janssen Re…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Ganoderma Spores Modulate the Gut-Brain Axis [NA]
A not-yet-recruiting clinical trial is evaluating Ganoderma spores as a potential modulator of the gut-brain axis in depression and thyroid …
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Predictors and Clinical Outcomes of Patients With Coronary Heart Disease Co-morbid Depression Post Percutaneous Coronary Intervention
Clinical trial update evaluating predictors and clinical outcomes in patients with coronary heart disease and co-morbid depression after per…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study to Explore the Efficacy of JNJ-89495120 in the Treatment of Major Depressive Disorder [Phase 2]
A Phase 2 clinical trial assessing the efficacy of JNJ-89495120 for Major depressive disorder; the study is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: CAMH PARTNERs Integrated Care Study [NA]
The CAMH PARTNERs Integrated Care Study is currently active but not recruiting. It investigates integrated care approaches for depression, a…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Evaluation of a Collaborative Behavioral Health Program Implementation in Primary Care
Clinical trial update describing the evaluation of a collaborative behavioral health program implemented in primary care to address depressi…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Racial Disparities in Antidepressant Treatment After a Psychiatric Consultation
This clinical trial update describes ongoing research into racial disparities in antidepressant treatment after psychiatric consultation.
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Evaluation of an Online ACT and Compassion-based Intervention for Disorders of Gut-Brain Interaction [NA]
A clinical trial is evaluating an online Acceptance and Commitment Therapy (ACT) and compassion-based intervention for disorders of gut-brai…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Voice Activated Personal Assistant for Depression Among Older Adults [NA]
This ClinicalTrials.gov entry describes an active-but-not-recruiting study evaluating a voice-activated personal assistant for depression in…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Behavioral Telehealth in Low-resource Primary Care Settings for Anxiety and Depression in Youth [NA]
A study evaluating behavioral telehealth in low-resource primary care settings for anxiety and depression in youth is currently enrolling by…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Community-based Approach to Lowering Stress Through Mindfulness [NA]
Northwestern University is recruiting participants for a community-based mindfulness program aimed at lowering stress, with potential releva…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Pilot Study of Personalized Aperiodic Transcranial Alternating Current Stimulation in Antenatal Depression (PandA-tACS) [NA]
Pilot clinical trial evaluating personalized aperiodic transcranial alternating current stimulation for antenatal depression, currently recr…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: IBDminds - Mapping the Influence of aNxiety and DepreSsion on IBD
This clinical trial update indicates the IBDminds study, which investigates how anxiety and depression influence inflammatory bowel disease,…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Retrospective Analyses of the Greenbrook Database Evaluating Mental Health Treatments
A clinical trial update describes retrospective analyses of the Greenbrook Database evaluating mental health treatments, sponsored by Neuron…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Evaluating Conversational Artificial Intelligence for Depression Management [NA]
George Mason University is evaluating a conversational AI system for depression management in a clinical trial that is not yet recruiting.
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Collaborative Care Intervention for Cancer Patients and Their Family Caregivers -LITE [NA]
This NOT_YET_RECRUITING clinical trial is testing a collaborative care intervention for cancer patients and their family caregivers (LITE).
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Retrospective Analyses of TrakStar Database
A clinical trial update describing retrospective analyses of the TrakStar database in depression and obsessive-compulsive disorder, with Neu…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Resources, Inspiration, Support and Empowerment (RISE) for Black Pregnant Women [Phase 2, Phase 3]
Phase 2/Phase 3 clinical trial named RISE for Black Pregnant Women, sponsored by Cedars-Sinai, studying pregnancy-related mental health (dep…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Pharmacogenetic-Guided Antidepressant Treatment in Depression [NA]
A clinical trial update for pharmacogenetic-guided antidepressant treatment in major depressive disorder, with the study currently not yet r…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: SER Familia: A Family-Based Intervention Addressing Syndemic Conditions Among Latino Immigrant Families [NA]
Duke University is conducting a family-based intervention (SER Familia) to address syndemic conditions—including substance use, intimate par…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Prevention of Alzheimer's Disease With CR Plus tDCS in Mild Cognitive Impairment and Depression (PACt-MD) [NA]
The PACt-MD clinical trial investigates whether CR Plus transcranial direct current stimulation can help prevent Alzheimer's disease in indi…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Youth Emotional and Behavioral Treatment Study [NA]
Clinical trial update for a youth emotional and behavioral treatment study sponsored by Florida State University. The study investigates dep…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Anesthesia-Masked Psilocybin Therapy for Major Depression [Phase 2]
Stanford University's Phase 2 trial of anesthesia-masked psilocybin therapy for major depressive disorder is currently not recruiting.
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: A Study of the Effectiveness and Safety of JS1-1-01 Tablet in Patients With Moderate to Severe Depression [Phase 2, Phase 3]
A phase 2/3 clinical trial is evaluating the effectiveness and safety of JS1-1-01 Tablet for moderate-to-severe depression; the study is not…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: An Evaluation of the Impact of Pharmacist Comprehensive Medication Management With Pharmacogenomic Results to Improve Depression Outcomes in Community Pharmacies. [NA]
This clinical trial update investigates whether pharmacist comprehensive medication management guided by pharmacogenomic results can improve…