Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-05-04Clinical Trial Update: Imaging to Improve Brain Stimulation
A VA-sponsored clinical trial titled Imaging to Improve Brain Stimulation is studying Major depressive disorder and is currently active but …
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CLINICAL_TRIALS research · 2025-05-04Clinical Trial Update: Evaluation of the Efficacy and Safety of Subcutaneous Ketamine in the Treatment of Depressive Episode With Suicidal Ideation and/or Behavior in Adolescents [Phase 3]
Phase 3 trial evaluating the efficacy and safety of subcutaneous ketamine for depressive episodes with suicidal ideation/behavior in adolesc…
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CLINICAL_TRIALS research · 2025-05-04Clinical Trial Update: Dallas 2K: A Natural History Study of Depression
Dallas 2K is a natural history study of depression sponsored by the University of Texas Southwestern Medical Center, currently recruiting.
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CLINICAL_TRIALS research · 2025-05-04Clinical Trial Update: Teen Brain Online II: Understanding How Social Media Affects the Teen Brain [NA]
A ClinicalTrials.gov update shows the Teen Brain Online II study, examining how social media affects the teen brain, is currently recruiting…
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CLINICAL_TRIALS research · 2025-05-02Clinical Trial Update: RCT Protocol for 'OverThinking': A Mobile EMI for Reducing Experiential Avoidance [NA]
A protocol for a mobile ecological momentary intervention to reduce experiential avoidance in people with depression and anxiety, with study…
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CLINICAL_TRIALS research · 2025-05-02Clinical Trial Update: Relief From Stress Via Social Protection in Senegal [NA]
Georgetown University-sponsored clinical trial in Senegal is studying relief from stress via social protection for distress, major depressiv…
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CLINICAL_TRIALS research · 2025-05-01Clinical Trial Update: Substance Consumption, Personality, and Cognitive Functioning of Chess Players
A completed clinical trial evaluating substance use, personality traits, and cognitive functioning in chess players.
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CLINICAL_TRIALS research · 2025-05-01Clinical Trial Update: Deciphering Principles of Network Dynamics Underlying Depression Symptom Severity From Multi-day Intracranial Recordings in Patients With Major Depression
This completed clinical trial studies how brain network dynamics, measured via multi-day intracranial recordings, relate to depression sympt…
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CLINICAL_TRIALS research · 2025-05-01Clinical Trial Update: Ambulatory Electrodermal Activity Measurements as Part of Identification and Prevention of Job Burnout
A Tampere University Hospital-led clinical trial is evaluating ambulatory electrodermal activity measurements to help identify and prevent j…
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CLINICAL_TRIALS research · 2025-05-01Clinical Trial Update: Effects of Intranasal Ketamine on Depression and Anxiety in Palliative Care Cancer Patients [EARLY_Phase 1]
This is an early Phase 1 clinical trial evaluating intranasal ketamine for depressive symptoms and anxiety in cancer patients receiving pall…
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CLINICAL_TRIALS research · 2025-05-01Clinical Trial Update: Home-based Non-invasive Brain Stimulation for Treatment-resistant Depression Feasibility, Efficacy and Biomarker of Treatment Response [NA]
This clinical trial update describes a feasibility and efficacy study of home-based non-invasive brain stimulation for treatment-resistant m…
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CLINICAL_TRIALS research · 2025-04-30Clinical Trial Update: Kintsugi Voice Device Pivotal Study
Recruitment is underway for a pivotal study evaluating the Kintsugi Voice Device for depression across multiple severities. The trial is cur…
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CLINICAL_TRIALS research · 2025-04-30Clinical Trial Update: Physical Activity Program for TRD [NA]
Clinical trial investigating a physical activity program for treatment-resistant depression and major depressive disorder; currently recruit…
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CLINICAL_TRIALS research · 2025-04-29Clinical Trial Update: Combining Light Therapy and CPAP in Depression [NA]
This trial investigates combining light therapy with CPAP for major depressive disorder and obstructive sleep apnea-related sleep disturbanc…
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CLINICAL_TRIALS research · 2025-04-27Clinical Trial Update: A Study to Investigate the Antidepressant Mechanism-of-action of JNJ-42847922 in Participants With Major Depressive Disorder [Phase 1]
This entry reports the completion of a Phase 1 study investigating the antidepressant mechanism-of-action of Janssen's JNJ-42847922 in adult…
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CLINICAL_TRIALS research · 2025-04-27Clinical Trial Update: Pharmacogenetic-Guided Antidepressant Prescribing in Adolescents With Anxiety and Depression [NA]
This clinical trial investigates pharmacogenetic-guided prescribing of antidepressants for adolescents with anxiety and depression and is cu…
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CLINICAL_TRIALS research · 2025-04-27Clinical Trial Update: A Study to Describe Routine Treatment Pathways in Participants With Major Depression and Active Suicidal Ideation With Intent in Italy
A completed clinical trial update describing a study conducted in Italy to describe routine treatment pathways for adults with major depress…
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CLINICAL_TRIALS research · 2025-04-25Clinical Trial Update: Mental Health and PreP [NA]
A clinical trial is planned to study Major Depressive Disorder in individuals taking PrEP, sponsored by Assistance Publique - Hôpitaux de Pa…
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CLINICAL_TRIALS research · 2025-04-25Clinical Trial Update: Treatment With Psilocybin for Chronic Neuropathic Pain and Depression (TRANSCEND) [Phase 2]
A Phase 2 clinical trial investigating psilocybin for treatment-resistant depression and chronic pain is currently recruiting.
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CLINICAL_TRIALS research · 2025-04-25Clinical Trial Update: Does Psilocybin Require Psychedelic Effects to Treat Depression? [Phase 2]
A Phase 2 clinical trial is exploring whether psilocybin's psychedelic effects are necessary to treat treatment-resistant depression, and th…
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CLINICAL_TRIALS research · 2025-04-24Clinical Trial Update: Leucine in Midlife Depression [Phase 2]
A Phase 2 trial from Emory University is evaluating leucine for midlife depression and is currently recruiting.
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CLINICAL_TRIALS research · 2025-04-24Clinical Trial Update: Dose-Finding Clinical Trial to Evaluate the Efficacy and Safety of LV232 Capsules in the Treatment of MDD [Phase 2]
A Phase 2 dose-finding trial is evaluating the efficacy and safety of LV232 capsules for major depressive disorder. The study is currently r…
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CLINICAL_TRIALS research · 2025-04-24Clinical Trial Update: Youth Depression and Suicide Research Network
This update indicates that the Youth Depression and Suicide Research Network is currently enrolling by invitation to study depression and su…
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CLINICAL_TRIALS research · 2025-04-24Clinical Trial Update: Sensory Synchronized Imaging and Neuromodulation [NA]
A new clinical trial investigating sensory synchronized imaging and neuromodulation for major depressive disorder is currently recruiting.
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CLINICAL_TRIALS research · 2025-04-24Clinical Trial Update: Temporal Interference and Depression [NA]
This clinical trial update shows that a study on Temporal Interference for Major depressive disorder is currently recruiting. The phase is n…