Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-05-16Clinical Trial Update: Trauma-Focused Cognitive Behavioral Therapy in Unaccompanied Refugee Minors With PTSD in Greece: An RCT [NA]
An ongoing randomized trial in Greece is evaluating trauma-focused cognitive behavioral therapy for post-traumatic stress disorder and relat…
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CLINICAL_TRIALS research · 2025-05-16Clinical Trial Update: Ketogenic Metabolic Therapy in Schizophrenia, Bipolar Disorder, Major Depressive Disorder: Deep Omic Profiling [NA]
A Stanford University-sponsored trial investigates ketogenic metabolic therapy (ketogenic dieting) for schizophrenia, bipolar disorder, and …
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CLINICAL_TRIALS research · 2025-05-15Clinical Trial Update: Patient- and Family-centred Care in the Adult Intensive Care Unit: a Feasibility Study [NA]
A feasibility study investigating patient- and family-centered care in the adult intensive care unit, sponsored by Herlev Hospital; the tria…
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CLINICAL_TRIALS research · 2025-05-15Clinical Trial Update: SKY Breath Intervention
A UCSF-sponsored study of the SKY Breath Intervention is currently active but not recruiting, evaluating its effects on depression and anxie…
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CLINICAL_TRIALS research · 2025-05-14Clinical Trial Update: Psilocybin With Pimavanserin Compared to Psilocybin Alone for the Treatment of Major Depressive Disorder [Phase 2]
Phase 2 clinical trial update comparing psilocybin with pimavanserin versus psilocybin alone for major depressive disorder; recruitment is o…
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CLINICAL_TRIALS research · 2025-05-14Clinical Trial Update: Skills for Wellness [NA]
This is a clinical trial update for the Skills for Wellness study. It is currently recruiting participants with schizophrenia, bipolar disor…
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CLINICAL_TRIALS research · 2025-05-14Clinical Trial Update: Exercise to Augment TMS in Those With Treatment Resistant Depression [NA]
A clinical trial update describes a study evaluating exercise as an adjunct to transcranial magnetic stimulation for treatment-resistant dep…
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CLINICAL_TRIALS research · 2025-05-14Clinical Trial Update: Personalized Indications for CBT and Antidepressants in Treating Depression [Phase 4]
This clinical trial update outlines a Phase 4 study exploring personalized indications for cognitive behavioral therapy (CBT) and antidepres…
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CLINICAL_TRIALS research · 2025-05-14Clinical Trial Update: The Canadian Depression Research and Intervention Network (CDRIN) Maritimes Registry
Clinical trial update announcing the CDRIN Maritimes Registry, a prospective registry for depression and trauma-related disorders, currently…
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CLINICAL_TRIALS research · 2025-05-14Clinical Trial Update: Genetic Counselling in the Prevention of Mental Health Consequences of Cannabis Use [NA]
A clinical trial evaluating whether genetic counselling can prevent mental health problems associated with cannabis use; the study is curren…
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CLINICAL_TRIALS research · 2025-05-14Clinical Trial Update: Accelerated iTBS for Depression: Monitoring Brain Hemodynamics With Simultaneous iTBS/fNIRS [NA]
A clinical trial evaluating accelerated intermittent theta-burst stimulation (iTBS) for depression with concurrent fNIRS-based monitoring of…
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CLINICAL_TRIALS research · 2025-05-14Clinical Trial Update: DBS for Depression [NA]
A Baylor College of Medicine study is recruiting participants for a deep brain stimulation trial to treat major depressive disorder. The ent…
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CLINICAL_TRIALS research · 2025-05-13Clinical Trial Update: Psilocybin Therapy for Depression in Parkinson's Disease [Phase 2]
Phase 2 clinical trial evaluating psilocybin therapy for depression in Parkinson's disease is currently recruiting. The study investigates p…
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CLINICAL_TRIALS research · 2025-05-13Clinical Trial Update: Adjuvant Accelerated piTBS for Reducing Suicidal Ideation in TRD Patients [NA]
Clinical trial update on an adjuvant accelerated piTBS approach to reduce suicidal ideation in patients with treatment-resistant major depre…
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CLINICAL_TRIALS research · 2025-05-13Clinical Trial Update: Taiwan Post-Stroke Disability Study
Taiwan-based post-stroke disability study led by National Taiwan University Hospital is currently recruiting participants.
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CLINICAL_TRIALS research · 2025-05-11Clinical Trial Update: Reducing Suicide Risk Among Aging Caregivers of Persons With AD/ADRD [NA]
This clinical trial update shows ongoing recruitment for a study to reduce suicide risk and depressive symptoms among aging caregivers of pe…
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CLINICAL_TRIALS research · 2025-05-08Clinical Trial Update: Comparison of Esketamine/Propofol and Methohexital Anesthesia for ECT [Phase 4]
Phase 4 clinical trial evaluating esketamine/propofol anesthesia versus methohexital anesthesia for electroconvulsive therapy in depression;…
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CLINICAL_TRIALS research · 2025-05-08Clinical Trial Update: Effects of Low-intensity Transcranial Magnetic Stimulation on Major Depressive Disorder, and on 5-hydroxyindoleacetic Acid and Brain-derived Neurotrophic Factor Levels [Phase 1, Phase 2]
An ongoing Phase 1/2 clinical trial from Universidad de Guanajuato is evaluating the effects of low-intensity transcranial magnetic stimulat…
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CLINICAL_TRIALS research · 2025-05-07Clinical Trial Update: Neural Correlates of Stress and Perceived Control in Adolescent Depression [NA]
A McLean Hospital clinical trial investigating neural correlates of stress and perceived control in adolescents with major depressive disord…
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CLINICAL_TRIALS research · 2025-05-07Clinical Trial Update: Cognitive Dysfunction and Inflammation in Depression: Experimental Inhibition Via Infliximab [Phase 2]
Phase 2 clinical trial from Massachusetts General Hospital evaluating infliximab to address cognitive dysfunction and inflammation in major …
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CLINICAL_TRIALS research · 2025-05-06Clinical Trial Update: The Effects of Psilocybin on Self-Focus and Self-Related Processing in Major Depressive Disorder [Phase 3]
Phase 3 clinical trial evaluating the effects of psilocybin on self-focus and self-related processing in Major Depressive Disorder; currentl…
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CLINICAL_TRIALS research · 2025-05-06Clinical Trial Update: Resilience in Adolescent Development
A University of Texas Southwestern Medical Center–sponsored clinical trial is recruiting adolescents to study resilience development and its…
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CLINICAL_TRIALS research · 2025-05-06Clinical Trial Update: The OBSERVE Protocol
Clinical trial update announcing the OBSERVE protocol for major depressive disorder, with recruitment ongoing at Yale University.
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CLINICAL_TRIALS research · 2025-05-06Clinical Trial Update: Modified Interactive Screening Program Plus MINDBODYSTRONG: A Mental Health Resiliency Intervention for Nurses [NA]
This clinical trial update describes a mental health resiliency intervention for nurses that combines a Modified Interactive Screening Progr…
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CLINICAL_TRIALS research · 2025-05-06Clinical Trial Update: A Trial of Dextromethorphan and Bupropion Sustained-Release Tablets in Patients With Major Depressive Disorder [Phase 3]
Phase 3 study evaluating a dextromethorphan and bupropion sustained-release tablet for major depressive disorder; currently recruiting.