Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-06-12Clinical Trial Update: Inhibitory Mechanisms of Negative Urgency in Adolescent Suicidal Behavior [NA]
A University of Minnesota clinical trial is recruiting to study the inhibitory mechanisms of negative urgency in adolescent suicidal behavio…
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CLINICAL_TRIALS research · 2025-06-11Clinical Trial Update: Testing a Transdiagnostic TMS Treatment Target [EARLY_Phase 1]
An early-phase Phase 1 trial evaluating a transdiagnostic TMS treatment across multiple psychiatric conditions, including major depressive d…
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CLINICAL_TRIALS research · 2025-06-11Clinical Trial Update: Exercise Training for Managing Major Depressive Disorder in Multiple Sclerosis [NA]
A recruiting clinical trial at the University of Illinois at Chicago is evaluating exercise training as a management approach for major depr…
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CLINICAL_TRIALS research · 2025-06-11Clinical Trial Update: Adapting BA for Minimally Verbal Autistic Adults [NA]
A Rutgers-sponsored clinical trial is evaluating an adaptation of behavioral activation for minimally verbal adults with autism, with comorb…
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CLINICAL_TRIALS research · 2025-06-10Clinical Trial Update: A Study to Assess Serotonin Transporter Occupancy of Healthy Adults Using 11C-DASB PET [Phase 1]
A Phase 1 study in healthy adults assessing serotonin transporter occupancy using the PET tracer 11C-DASB.
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CLINICAL_TRIALS research · 2025-06-10Clinical Trial Update: Switching Medication and Augmentation Strategies for SSRI-Resistant Adolescent Depression（SMART-I) [Phase 4]
A Phase 4 clinical trial update is evaluating switching medications and augmentation strategies for adolescents with SSRI-resistant major de…
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CLINICAL_TRIALS research · 2025-06-10Clinical Trial Update: Assessment of Whether Telehealth Family Psychoeducation for Major Depressive Disorder is Doable [NA]
This clinical trial update describes a feasibility assessment to determine whether telehealth-based family psychoeducation for Major Depress…
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CLINICAL_TRIALS research · 2025-06-08Clinical Trial Update: A Pilot Study of Synbiotics in Adults With Depressive Symptoms [NA]
A pilot study evaluating a synbiotic formulation in adults with mild-to-moderate depressive symptoms is currently recruiting.
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CLINICAL_TRIALS research · 2025-06-06Clinical Trial Update: Probiotic Administration for Adolescent Depression [EARLY_Phase 1]
This document reports an early-phase 1 clinical trial investigating probiotic administration for adolescent depression, with recruitment ong…
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CLINICAL_TRIALS research · 2025-06-06Clinical Trial Update: Effectiveness of mHealth Post-discharge Intervention for Patients With Severe Mental Illness [NA]
This clinical trial update notes that enrollment is ongoing by invitation for a study evaluating a mobile health post-discharge intervention…
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CLINICAL_TRIALS research · 2025-06-06Clinical Trial Update: Cognitive Rehabilitation for Veterans With MDD-related Cognitive Functioning Deficits [NA]
A clinical trial update indicates a study is recruiting to evaluate cognitive rehabilitation for veterans with cognitive deficits related to…
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CLINICAL_TRIALS research · 2025-06-06Clinical Trial Update: Spatiotemporal Dynamics of the Human Emotion Network [NA]
A UCSF-led clinical trial is investigating the spatiotemporal dynamics of the human emotion network and is currently enrolling by invitation…
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CLINICAL_TRIALS research · 2025-06-06Clinical Trial Update: Therapy Dog Visits for Patients Hospitalized With Traumatic Injuries [NA]
A Boston Medical Center trial is evaluating therapy dog visits for patients hospitalized with traumatic injuries to support recovery and add…
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CLINICAL_TRIALS research · 2025-06-05Clinical Trial Update: PET Biomarker Study for Antidepressant Response Prediction in Major Depressive Disorder [NA]
This clinical trial outlines a PET biomarker study aimed at predicting antidepressant response in major depressive disorder. The study is no…
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CLINICAL_TRIALS research · 2025-06-05Clinical Trial Update: Effects and Cost-effectiveness of e-Meistring - a Guided Internet-delivered Psychological Treatment
This update describes a clinical trial evaluating the effects and cost-effectiveness of e-Meistring, a guided internet-delivered psychologic…
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CLINICAL_TRIALS research · 2025-06-05Clinical Trial Update: Early Speaking Valve in Ventilator Weaning: Effects on Communication, Depression, and Quality of Life [NA]
A clinical trial update notes a study on using an early speaking valve to assist ventilator weaning, focusing on communication, depression, …
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CLINICAL_TRIALS research · 2025-06-05Clinical Trial Update: Effects of Transcranial Direct Current Stimulation (tDCS) in the Management of Suicidal Ideation [NA]
A clinical trial (NCT06009523) is evaluating the effects of transcranial direct current stimulation for managing suicidal ideation in indivi…
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CLINICAL_TRIALS research · 2025-06-04Clinical Trial Update: Cognitive and Affective Processes Online
A University of Minnesota–sponsored online study examining cognitive and affective processes in individuals with major depressive disorder i…
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CLINICAL_TRIALS research · 2025-06-03Clinical Trial Update: Facilitated Transitions From Postpartum to Primary Care Coordination for People With Chronic Conditions [NA]
Massachusetts General Hospital is testing facilitated transitions from postpartum care to primary care coordination for people with chronic …
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CLINICAL_TRIALS research · 2025-06-03Clinical Trial Update: Local Participatory Systems Dynamics to Increase Reach of Evidence Based Addiction and Mental Health Care [NA]
A clinical trial using local participatory systems dynamics to broaden reach of evidence-based addiction and mental health care and is enrol…
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CLINICAL_TRIALS research · 2025-06-03Clinical Trial Update: Metabolic Profiling of Esketamine Treatment in Depressive Disorder
A clinical trial protocol evaluates metabolic profiling during Esketamine treatment for Major Depressive Disorder and is currently recruitin…
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CLINICAL_TRIALS research · 2025-06-03Clinical Trial Update: Ketamine for Postherpetic Neuralgia With Depression [Phase 4]
Phase 4 clinical trial evaluating ketamine for individuals with depression and postherpetic neuralgia; the study is currently not recruiting…
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CLINICAL_TRIALS research · 2025-05-31Clinical Trial Update: EMDR 2.0 Group Therapy for PTSD, Depression, and Anxiety in Earthquake Survivors [NA]
A completed clinical trial evaluating EMDR 2.0 group therapy for PTSD, depression, and anxiety in earthquake survivors.
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CLINICAL_TRIALS research · 2025-05-31Clinical Trial Update: Implementation of Project YES in Ambulatory Adolescent & Young Adult Medicine [NA]
Clinical trial update for Project YES in ambulatory adolescent and young adult medicine. Enrollment by invitation is ongoing for conditions …
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CLINICAL_TRIALS research · 2025-05-31Clinical Trial Update: Income Volatility and Mental Health, Full Experiment [NA]
Cornell University is conducting a recruiting clinical trial to study how income volatility relates to depression and anxiety, with enrollme…