Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Development of a College Student-Delivered Cognitive-Behavioral Therapy (CBT) Intervention for Rural High School Students [NA]
A study assessing a college student-delivered CBT intervention for rural high school students addressing depression, anxiety, and stress, wi…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Effects of a Salutogenic Strength-based Social Robot-assisted Intervention on the Depressive Symptoms and Sense of Coherence of Family Caregivers of Persons With Dementia [NA]
A registered clinical trial evaluating whether a salutogenic strength-based social robot-assisted intervention reduces depressive symptoms a…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Use of a Smartphone Mobile Application (App) to Enhance Smoking Cessation Treatment [NA]
A clinical trial update on using a smartphone app to enhance smoking cessation treatment, sponsored by MD Anderson, with conditions includin…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: CRISOL Mente: A Multilevel Community Intervention to Reduce Mental Health Disparities Among Latinos [NA]
Update on the CRISOL Mente trial, a multilevel community intervention to reduce mental health disparities among Latinos. The study is curren…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: NBI-1065845-MDD3026: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD) [Phase 3]
ClinicalTrials.gov update for the Phase 3 study NBI-1065845-MDD3026 evaluating NBI-1065845 as an adjunctive treatment in major depressive di…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND) [NA]
A clinical trial update indicating that Abbott Medical Devices is recruiting for TRANSCEND, a deep brain stimulation study targeting treatme…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Enhancing Veteran-Clinical Collaboration in VA PRRCs [NA]
A VA-sponsored initiative aims to enhance veteran-clinical collaboration within VA PRRCs; the study is currently not yet recruiting.
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: The Effects of Cognitive Behavioral Therapy on Insulin Resistance in People With HIV [NA]
This clinical trial update describes ongoing research into the effects of cognitive behavioral therapy on insulin resistance in adults with …
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Multi-component Family Intervention to Lower Depression and Address Intimate Partner Violence in Nepal [NA]
A clinical trial in Nepal is recruiting to test a multi-component family intervention designed to lower depression and address intimate part…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Cognitive Enhancement in Recurrent Depression (The COG-D-R Study) [NA]
A clinical trial from Vanderbilt University Medical Center seeks cognitive enhancement in recurrent depression; the study is currently not y…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Validity and Reliability of the Turkish Version of the Cardiac Depression Scale
A completed clinical trial evaluating the validity and reliability of the Turkish version of the Cardiac Depression Scale for individuals wi…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Efficacy and Safety of a Theta Burst Stimulation Protocol of Repetitive Transcranial Magnetic Stimulation in Treatment-Resistant Depression [NA]
This clinical trial update describes a theta burst stimulation protocol using repetitive transcranial magnetic stimulation for treatment-res…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Effects of Exercise and Virtual Reality on Depression [NA]
A clinical trial is evaluating whether exercise combined with virtual reality can reduce depressive symptoms in participants. The study is c…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Assessing Social Learning and Course Delivery Timing in Internet-delivered Cognitive Behaviour Therapy for Public Safety Personnel [NA]
This clinical trial update describes a study evaluating social learning and course delivery timing in internet-delivered cognitive behaviora…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Early Brainwave Biomarkers for Personalized Neuromodulation in Treatment-resistant Depression [NA]
A clinical trial registry entry describing research on early brainwave biomarkers to guide personalized neuromodulation for treatment-resist…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Phase 2 Study of Zelquistinel or Placebo for the Reduction of Symptoms of Major Depressive Disorder [Phase 2]
Phase 2 clinical trial evaluating Zelquistinel vs placebo for reducing symptoms of Major Depressive Disorder; currently recruiting.
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Dextromethorphan-Bupropion on Striatal Activity in Adults With Major Depressive Disorder [Phase 2]
Phase 2 clinical trial evaluating the dextromethorphan–bupropion combination for major depressive disorder, currently recruiting to assess s…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Phase 3 Study of Adjunctive Treatment With Seltorexant in Adult and Elderly Participants With Major Depressive Disorder and Insomnia Symptoms [Phase 3]
A Phase 3 study is underway to test adjunctive Seltorexant in adults with major depressive disorder and insomnia symptoms. The sponsor is Ja…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Digital CBT for Insomnia and Depression [NA]
A University of Rochester trial is evaluating digital cognitive-behavioral therapy for depression and insomnia. The study is currently recru…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Emotional Cognition: Establishing Constructs and Neural-Behavioral Mechanisms in Older Adults With Depression
This clinical trial update from UT Southwestern reports an ongoing study on emotional cognition and neural-behavioral mechanisms in older ad…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: IPT-based Group Intervention by Non-specialist for Improvement of Depressive Symptoms in Community Young Adults in Brazil [NA]
A Brazil-based clinical trial is evaluating an interpersonal psychotherapy (IPT) group intervention delivered by non-specialists to improve …
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: rTMS With and Without Text4Support for the Treatment of Resistant Depression. [NA]
A clinical trial update indicates recruiting for a study of repetitive transcranial magnetic stimulation (rTMS) with and without Text4Suppor…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Home-Based CR and tDCS to Enhance Cognition in Persons With Mild Cognitive Impairment and Late Life Depression [NA]
An update on a clinical trial testing home-based cognitive rehabilitation plus transcranial direct current stimulation to improve cognition …
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Esketamine for Reduction of Symptoms of Major Depressive Disorder [Phase 3]
This clinical trial update describes a Phase 3 study evaluating the efficacy and safety of esketamine for reducing symptoms of major depress…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Cancer Related Major Depression Treated With a Single Dose of Psilocybin [Phase 2]
A Phase 2 clinical trial is evaluating a single dose of psilocybin for cancer-related major depressive disorder, with recruitment ongoing.