Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-07-18Clinical Trial Update: Deep Brain Stimulation for Treatment Resistant Depression With the Medtronic Activa PC+S [NA]
Clinical trial update for deep brain stimulation using the Medtronic Activa PC+S in treatment-resistant depression; the study is currently a…
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CLINICAL_TRIALS research · 2025-07-18Clinical Trial Update: Amplification of Positivity for Alcohol Use [NA]
An ongoing clinical trial sponsored by the Laureate Institute for Brain Research evaluating a therapy for alcohol use disorder with comorbid…
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CLINICAL_TRIALS research · 2025-07-18Clinical Trial Update: Clinical Trial for Integrated Care to Help At Risk Teen (iCHART) Intervention [NA]
The University of Pittsburgh is recruiting adolescents for a clinical trial evaluating the Integrated Care iCHART intervention to reduce sui…
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CLINICAL_TRIALS research · 2025-07-17Clinical Trial Update: Effectiveness and Cost-Effectiveness of Depression Treatment for Individuals With TB in South Africa [NA]
This clinical trial update describes a study evaluating the effectiveness and cost-effectiveness of depression treatment among individuals w…
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CLINICAL_TRIALS research · 2025-07-17Clinical Trial Update: Evaluation Study of Medical-Social Collaboration Model for Middle-aged and Older Adults With Depressive Symptoms [NA]
An evaluation study by The University of Hong Kong is examining a medical-social collaboration model for depressive symptoms in middle-aged …
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CLINICAL_TRIALS research · 2025-07-17Clinical Trial Update: Benefits of Exergames on Neurocognitive Functions in Adults Suffering From Depression [NA]
MAP Institute is sponsoring a clinical trial to evaluate whether exergames improve neurocognitive function in adults with depression; the st…
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CLINICAL_TRIALS research · 2025-07-17Clinical Trial Update: Just-In-Time Adaptive Interventions (JITAIs) in a Digital Mental Health Intervention for Middle-Aged and Older Adults With Chronic Pain [NA]
This is an update on an ongoing clinical trial evaluating Just-In-Time Adaptive Interventions (JITAIs) in a digital mental health program fo…
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CLINICAL_TRIALS research · 2025-07-16Clinical Trial Update: Evaluating a Personalised Online Program With Human Support for Women With Depression and Its Impact on Mental Health and Biological Changes [NA]
A clinical trial evaluating a personalised online program with human support for women with depression and its impact on mental health and b…
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CLINICAL_TRIALS research · 2025-07-15Clinical Trial Update: Ketamine-Assisted Psychotherapy (KAP) Compared to Ketamine Alone for the Treatment of Depression [Phase 2]
This clinical trial update describes a Phase 2 study comparing Ketamine-Assisted Psychotherapy (KAP) to ketamine alone for Major Depressive …
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CLINICAL_TRIALS research · 2025-07-14Clinical Trial Update: Combining rTMS & Aerobic Exercise to Treat Depression and Improve Post-Stroke Walking [NA]
This clinical trial is recruiting to test combining repetitive transcranial magnetic stimulation (rTMS) with aerobic exercise to treat depre…
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CLINICAL_TRIALS research · 2025-07-14Clinical Trial Update: A Multicentre Clinical Study
A multicenter clinical study sponsored by Zhongda Hospital on objective diagnosis of depression; the trial is not yet recruiting.
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CLINICAL_TRIALS research · 2025-07-14Clinical Trial Update: Impact of Exercise Groups on Patient Mental Health and Wellbeing in an Acute Psychiatric Inpatient Unit [NA]
Johns Hopkins University reports an ongoing enrollment-by-invitation study evaluating the impact of structured exercise groups on mental hea…
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CLINICAL_TRIALS research · 2025-07-14Clinical Trial Update: Change My Story Task Shifted Mental Health Intervention [NA]
This clinical trial update notes a task-shifted mental health intervention called 'Change My Story' for people with HIV and depression, and …
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CLINICAL_TRIALS research · 2025-07-14Clinical Trial Update: A Computerized Depression Intervention in Veterans [NA]
A VA-sponsored clinical trial is testing a computerized depression intervention in veterans and is currently recruiting.
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CLINICAL_TRIALS research · 2025-07-11Clinical Trial Update: Neural-Derived Plasma Exosomal MicroRNAs As Promising Novel Biomarkers for Suicidality and Treatment Outcome in Adolescents [NA]
A University of Alabama at Birmingham study is evaluating neural-derived plasma exosomal microRNAs as biomarkers for suicidality and treatme…
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CLINICAL_TRIALS research · 2025-07-11Clinical Trial Update: Long Term Follow Up KET-PD
An ongoing Yale-sponsored long-term follow-up study (KET-PD) for Parkinson's disease, including depressive symptoms, is currently enrolling …
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CLINICAL_TRIALS research · 2025-07-10Clinical Trial Update: Predictors of Cognitive Outcomes in Geriatric Depression [Phase 4]
Phase 4 clinical trial update examining predictors of cognitive outcomes in older adults with major depressive disorder; the study is curren…
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CLINICAL_TRIALS research · 2025-07-10Clinical Trial Update: Evaluating Procedures for a Study of the AYA Survivors Coping and Emotional Needs Toolkit [NA]
Completed clinical trial evaluating procedures for a study of the AYA Survivors Coping and Emotional Needs Toolkit. The trial addressed depr…
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CLINICAL_TRIALS research · 2025-07-10Clinical Trial Update: Digital Mood-enhanced CBT-I to Improve Depressive Symptoms in Adolescents [NA]
A clinical trial is recruiting to evaluate a digital mood-enhanced CBT-I program designed to improve depressive symptoms in adolescents with…
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CLINICAL_TRIALS research · 2025-07-10Clinical Trial Update: 6 Weeks Right-Amygdala TIS for Depression [NA]
A clinical trial update indicates a study of right-amygdala TIS therapy for major depressive disorder is currently enrolling by invitation.
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CLINICAL_TRIALS research · 2025-07-10Clinical Trial Update: Caregiver Stress and Sleep Study [NA]
A University of Pittsburgh–led clinical trial is recruiting to study caregiver stress and sleep, assessing depressive symptoms and caregiver…
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CLINICAL_TRIALS research · 2025-07-09Clinical Trial Update: Music Interventions for Dementia and Depression in Elderly Care [NA]
A completed clinical trial evaluating music interventions for dementia and depression in elderly care settings. The sponsor is NORCE Norwegi…
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CLINICAL_TRIALS research · 2025-07-08Clinical Trial Update: Real-life Assessment of Brexpiprazole (Rexulti) in Schizophrenia and in Depressive Disorders
This clinical trial update reports a real-world assessment of brexpiprazole (Rexulti) for schizophrenia and depressive disorders, currently …
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CLINICAL_TRIALS research · 2025-07-08Clinical Trial Update: StratCare Trial 2: Evaluating the Clinical and Cost-effectiveness of AI-driven Stratified Care for Depression [NA]
This update covers StratCare Trial 2, which is evaluating the clinical and cost-effectiveness of AI-driven stratified care for depression. T…
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CLINICAL_TRIALS research · 2025-07-08Clinical Trial Update: Effectiveness of a Guided Mental Health Chatbot for Youth Living in Lithuania [NA]
A clinical trial in Lithuania is evaluating the effectiveness of a guided mental health chatbot for youth with symptoms of depression and an…