Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-08-11Clinical Trial Update: Biobank and Brain Health in Bordeaux.
A Bordeaux-based clinical trial is recruiting participants for a biobank study focused on brain health and aging, including cognitive aging …
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CLINICAL_TRIALS research · 2025-08-11Clinical Trial Update: Mechanisms of Rumination Change in Adolescent Depression [NA]
A clinical trial update from Ohio State University on mechanisms underlying rumination changes in adolescents with major depressive disorder…
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CLINICAL_TRIALS research · 2025-08-11Clinical Trial Update: Accelerated TMS for Treatment-Resistant ECT [NA]
A clinical trial is evaluating accelerated transcranial magnetic stimulation for treatment-resistant major depressive disorder and is curren…
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CLINICAL_TRIALS research · 2025-08-11Clinical Trial Update: Multimodal Identification of Depressive Symptoms in the Elderly
A clinical trial update about a study aimed at multimodal identification of depressive symptoms in the elderly, currently not yet recruiting…
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CLINICAL_TRIALS research · 2025-08-11Clinical Trial Update: Neuro-affective Response to Light in Depressed Adolescents and Young Adults [NA]
This clinical trial update indicates that the study investigating neuro-affective responses to light in depressed adolescents and young adul…
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CLINICAL_TRIALS research · 2025-08-08Clinical Trial Update: Disposition Kinetics of Dolutegravir Among People Living With HIV With Major Depression in Nigeria [Phase 4]
Phase 4 clinical trial update on disposition kinetics of dolutegravir in people living with HIV who have major depression in Nigeria; the st…
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CLINICAL_TRIALS research · 2025-08-08Clinical Trial Update: Avatar Therapy in Virtual Reality for Treatment-Resistant Major Depressive Disorder: A Pilot Study [NA]
This document provides an update on a pilot study of avatar therapy in virtual reality for treatment-resistant major depressive disorder, wi…
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CLINICAL_TRIALS research · 2025-08-08Clinical Trial Update: A Study of Ketamine Infusions to Treat Clinically-depressed ICU Patients [Phase 2]
This clinical trial update reports that a Phase 2 study is evaluating ketamine infusions to treat depression in ICU patients, with recruitme…
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CLINICAL_TRIALS research · 2025-08-08Clinical Trial Update: 5-HTP and Creatine for Depression R33 Phase [Phase 2]
Clinical trial update for a Phase 2 study (R33) evaluating 5-HTP and creatine for major depressive disorder; recruitment is ongoing.
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CLINICAL_TRIALS research · 2025-08-08Clinical Trial Update: Neuromodulation and Attention Deficits in MDD [NA]
A neuromodulation study from the University of Electronic Science and Technology of China is recruiting to address attention deficits in ind…
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CLINICAL_TRIALS research · 2025-08-06Clinical Trial Update: COMpassion for Psychiatric Disorders And Self-Stigma [NA]
A clinical trial update for the COMpassion for Psychiatric Disorders And Self-Stigma study conducted by University Hospital Strasbourg, curr…
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CLINICAL_TRIALS research · 2025-08-06Clinical Trial Update: Mental Health in Primary Care [NA]
Ongoing University of Miami clinical trial in primary care assessing depression, anxiety, suicidality, and substance use; currently recruiti…
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CLINICAL_TRIALS research · 2025-08-05Clinical Trial Update: taVNS or TMS or Both for Depression [NA]
This update indicates that a study is recruiting to assess taVNS or transcranial magnetic stimulation (TMS), alone or in combination, for de…
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CLINICAL_TRIALS research · 2025-08-03Clinical Trial Update: Fixed Order, Open-Label, Dose-Escalation Study of DMT in Humans [Phase 1]
Yale University is conducting a fixed-order, open-label, dose-escalation Phase 1 trial of dimethyltryptamine (DMT). The study targets indivi…
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CLINICAL_TRIALS research · 2025-08-03Clinical Trial Update: Augmentation of EMDR With tDCS in the Treatment of Fibromyalgia [NA]
This is a clinical trial update describing a study that combines EMDR therapy with transcranial direct current stimulation (tDCS) for fibrom…
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CLINICAL_TRIALS research · 2025-08-03Clinical Trial Update: Multi-Omic, Clinomic and Digitomic Attributes of Major Depression for Integrative Analytics
Mayo Clinic is conducting a multi-omic, clinomic, and digitomic study of major depressive disorder to enable integrative analytics; the tria…
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CLINICAL_TRIALS research · 2025-08-03Clinical Trial Update: A Phase 2 Study to Evaluate Efficacy and Safety of KH607 Tablets in Adult Participents With Major Depressive Disorder [Phase 2]
A Phase 2 clinical trial is evaluating the efficacy and safety of KH607 tablets for adults with Major Depressive Disorder, with the study cu…
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CLINICAL_TRIALS research · 2025-08-01Clinical Trial Update: Chart Review of Patients Undergoing Ketamine Treatments for Depression
A completed chart-review study examining outcomes for patients with major depressive disorder who underwent ketamine treatments for depressi…
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CLINICAL_TRIALS research · 2025-07-31Clinical Trial Update: PET Imaging Using the Tracer [18F]VAT to Assess the Antidepressant Effect of Nicotine. [Phase 4]
A Phase 4 trial at Stony Brook University is recruiting to assess the antidepressant effects of nicotine in Major Depressive Disorder using …
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CLINICAL_TRIALS research · 2025-07-31Clinical Trial Update: Suicide Specific Rumination in Veterans [NA]
The update describes a recruiting clinical trial evaluating suicide-specific rumination in veterans with depression and mood disorders.
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CLINICAL_TRIALS research · 2025-07-31Clinical Trial Update: A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease
A non-interventional pilot study by ProgenaBiome exploring the role of the gut microbiome across multiple diseases; the study is currently s…
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CLINICAL_TRIALS research · 2025-07-31Clinical Trial Update: Accelerated rTMS for Substance Use Disorder and Depression [NA]
A clinical trial is evaluating accelerated repetitive transcranial magnetic stimulation (rTMS) for stimulant use disorder and depression, cu…
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CLINICAL_TRIALS research · 2025-07-31Clinical Trial Update: Project 2: Optimizing Engagement and Outcomes in STAND Digital Therapy [NA]
This clinical trial update indicates that the STAND Digital Therapy project is currently recruiting for a study on depression and anxiety sp…
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CLINICAL_TRIALS research · 2025-07-31Clinical Trial Update: Nitrous Oxide and EMOtional Cognition [NA]
A clinical trial update shows a nitrous oxide study recruiting for depression, sponsored by the University of Oxford.
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CLINICAL_TRIALS research · 2025-07-30Clinical Trial Update: Type I Hybrid Effectiveness-Implementation Trial of Primary Care Brief Mindfulness Training for Veterans [NA]
This Type I hybrid effectiveness-implementation trial evaluates a brief mindfulness training delivered in primary care for veterans with PTS…