Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-09-19Clinical Trial Update: Neurophysiological RCT of Qigong in Elderly With Depression [NA]
Clinical trial update for a randomized, neurophysiological study of qigong in elderly individuals with depression; sponsored by The Hong Kon…
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CLINICAL_TRIALS research · 2025-09-19Clinical Trial Update: Follow-up Study With Clinical Vitamin D Supplementation Trial on Patients With Depression (DepFuD) [NA]
Follow-up study evaluating Vitamin D supplementation in patients with depression; the trial is currently active but not recruiting.
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CLINICAL_TRIALS research · 2025-09-19Clinical Trial Update: Evaluating the Impact of Focused Muscle Contraction Therapy in U.S. Veterans [NA]
A clinical study by the University of Illinois at Chicago is evaluating Focused Muscle Contraction Therapy in U.S. veterans for chronic pain…
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CLINICAL_TRIALS research · 2025-09-19Clinical Trial Update: Pain and Major Depressive Disorder [NA]
A UCLA-sponsored clinical trial is currently recruiting to study treatments impacting both major depressive disorder and chronic pain.
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CLINICAL_TRIALS research · 2025-09-19Clinical Trial Update: Efficacy of Metformin as an Adjunct to Standard Antidepressant Therapy in Treating Depression Among Obese Patients [Phase 4]
A Phase 4 clinical trial is evaluating metformin as an adjunct to standard antidepressant therapy for depression in obese adults, with recru…
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CLINICAL_TRIALS research · 2025-09-19Clinical Trial Update: The PredictPlusPrevent Study [NA]
A clinical trial update for the PredictPlusPrevent study sponsored by The Mediterranean Institute for the Advance of Biotechnology and Healt…
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CLINICAL_TRIALS research · 2025-09-19Clinical Trial Update: TrueBlue Clinical Study - Investigating the Use of a Mobile Phone App TrueBlue for Monitoring Depression and Anxiety [NA]
This update describes a clinical trial evaluating the TrueBlue mobile app for monitoring depression and anxiety; recruitment is ongoing.
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CLINICAL_TRIALS research · 2025-09-19Clinical Trial Update: Evaluating and Implementing The CONNECT Program - a Group-Based Telehealth Intervention to Reduce Social Isolation, Loneliness, and Mental Health Symptoms in Adults Ages 55+, Compared to Routine Community-Based Programming [NA]
A clinical trial update on the CONNECT program, a group-based telehealth intervention aimed at reducing loneliness, social isolation, and me…
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CLINICAL_TRIALS research · 2025-09-18Clinical Trial Update: Mechanisms Underlying Antidepressant Effects of Physical Activity [NA]
A clinical trial is investigating the mechanisms by which physical activity may produce antidepressant effects. It is currently recruiting p…
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CLINICAL_TRIALS research · 2025-09-18Clinical Trial Update: The Improvement of Low-dose Esketamine on Postoperative Depression in Patients Undergoing Bariatric Surgery With Preoperative Depression [Phase 4]
A Phase 4 clinical trial assessing whether low-dose esketamine can improve postoperative depression in patients undergoing bariatric surgery…
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CLINICAL_TRIALS research · 2025-09-18Clinical Trial Update: Comparing Cognitive-Behavioral Therapy Versus Mindfulness-Based Therapy for Autistic Adults [NA]
A clinical trial comparing Cognitive-Behavioral Therapy with Mindfulness-Based Therapy for autistic adults is currently recruiting, includin…
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CLINICAL_TRIALS research · 2025-09-18Clinical Trial Update: Digital Intervention for Physical Activity [NA]
A clinical trial is investigating a digital intervention to promote physical activity for people with major depressive disorder and anxiety;…
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CLINICAL_TRIALS research · 2025-09-17Clinical Trial Update: Treatment of Major Depressive Disorder With Bilateral Theta Burst Stimulation [NA]
Completed clinical trial evaluating bilateral theta burst stimulation for Major Depressive Disorder.
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CLINICAL_TRIALS research · 2025-09-17Clinical Trial Update: Neurobiological Investigations of Mindfulness, Depression and Sleep Disturbances in Medical Staffs and Community Elders [NA]
A study sponsored by Taipei Medical University Shuang Ho Hospital is currently recruiting to explore neurobiological aspects of mindfulness,…
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CLINICAL_TRIALS research · 2025-09-17Clinical Trial Update: Interpersonal Psychotherapy-Based Counseling for Hemodialysis Patients: Effect on Adjustment and Depression [NA]
A completed clinical trial from Baskent University assessed whether interpersonal psychotherapy-based counseling improves adjustment and red…
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CLINICAL_TRIALS research · 2025-09-17Clinical Trial Update: Screening and Referral Practices for Anxiety and Depression Among Patients With Chronic Neck, Shoulder and Low Back Pain Within Physiotherapy Practices
An ongoing clinical trial update examining how screening and referral practices for anxiety and depression are integrated into physiotherapy…
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CLINICAL_TRIALS research · 2025-09-17Clinical Trial Update: Efficacy and Safety of Bupropion Hydrobromide in Adolescents and Children With Major Depressive Disorder [Phase 4]
A Phase 4 clinical trial update evaluating the efficacy and safety of bupropion hydrobromide in adolescents and children with major depressi…
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CLINICAL_TRIALS research · 2025-09-17Clinical Trial Update: Linking Affective Dynamics in Response to Daily Stress to Peripheral Vascular Function in Working Age Adults [NA]
This clinical trial investigates how affective responses to daily stress relate to peripheral vascular function in working-age adults with M…
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CLINICAL_TRIALS research · 2025-09-16Clinical Trial Update: The Motor Activity - Subjective Energy (MASE) Project [NA]
Clinical trial update for the Motor Activity - Subjective Energy (MASE) Project investigating major depressive disorder; currently recruitin…
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CLINICAL_TRIALS research · 2025-09-16Clinical Trial Update: Low Amplitude Pulse Seizure Therapy Versus Standard Ultra-Brief Right Unilateral Electroconvulsive Therapy [Phase 2, Phase 3]
A Phase 2/3 clinical trial at Michigan State University is evaluating low amplitude pulse seizure therapy versus standard ultra-brief right …
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CLINICAL_TRIALS research · 2025-09-16Clinical Trial Update: Cognitive Enhancement in Depression (The COG-D Study) [NA]
The COG-D Study conducted by Vanderbilt University Medical Center has completed a clinical trial evaluating cognitive enhancement in depress…
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CLINICAL_TRIALS research · 2025-09-16Clinical Trial Update: Psychological Adjustment to Long-term (PAL) Physical Conditions: A Randomised Cross-over Feasibility Trial of a Self-guided App [NA]
A randomized cross-over feasibility trial evaluating a self-guided app (PAL) to help people adjust to long-term physical conditions, with re…
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CLINICAL_TRIALS research · 2025-09-16Clinical Trial Update: Developing an Immersive Virtual Reality Platform [NA]
A clinical trial update describing development of an immersive virtual reality platform to support pregnant individuals, including those wit…
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CLINICAL_TRIALS research · 2025-09-15Clinical Trial Update: Cancer Pain Management Using a Web-based Intervention [NA]
A clinical trial is evaluating a web-based intervention for cancer pain management in people with breast cancer and depression; the study is…
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CLINICAL_TRIALS research · 2025-09-15Clinical Trial Update: Implementation of Problem-Solving Treatment in Community Health Centers (PST-Aid) [NA]
A University of Washington trial update reports recruitment for PST-Aid, a problem-solving treatment, aimed at depression in community healt…