Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-10-29Clinical Trial Update: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD) [Phase 3]
A Phase 3 clinical trial to evaluate the efficacy and safety of NBI-1065845 as adjunctive therapy for adults with Major Depressive Disorder …
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CLINICAL_TRIALS research · 2025-10-29Clinical Trial Update: Cannabis, Neuroinflammation, and Suicidal Ideation: A Supplemental Brain Imaging Study
A supplemental brain imaging study is investigating how cannabis use, neuroinflammation, and suicidal ideation relate to PTSD and depressive…
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CLINICAL_TRIALS research · 2025-10-29Clinical Trial Update: WellPATH-PREVENT: A Mobile Intervention for Middle-Aged and Older Adults Hospitalized for Suicidal Ideation or Attempt [NA]
This update indicates WellPATH-PREVENT, a mobile intervention trial, is currently recruiting middle-aged and older adults hospitalized for s…
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CLINICAL_TRIALS research · 2025-10-29Clinical Trial Update: A Mobile Health Intervention to Improve Psychosocial Functioning in Veterans With Posttraumatic Stress Disorder and Depression Symptoms [NA]
A clinical trial evaluating a mobile health intervention aimed at improving psychosocial functioning in veterans with post-traumatic stress …
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CLINICAL_TRIALS research · 2025-10-29Clinical Trial Update: Ovarian Hormone Withdrawal, Anhedonia, and Reward Sensitivity in Women With Premenstrual Exacerbations of Depression [Phase 4]
Phase 4 clinical trial evaluating how ovarian hormone withdrawal influences anhedonia and reward sensitivity in women with premenstrual exac…
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CLINICAL_TRIALS research · 2025-10-28Clinical Trial Update: Accelerated Neuromodulation of Anterior Cingulate Cortex for Depression [NA]
A clinical trial is currently recruiting to test accelerated neuromodulation of the anterior cingulate cortex for major depressive disorder.
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CLINICAL_TRIALS research · 2025-10-27Clinical Trial Update: Deep TMS for Comorbid Depression and Cognitive Impairment in Older Adults [NA]
Ongoing study evaluating Deep Transcranial Magnetic Stimulation (Deep TMS) for comorbid depression and cognitive impairment in older adults;…
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CLINICAL_TRIALS research · 2025-10-24Clinical Trial Update: Slow Wave Induction by Propofol to Eliminate Depression (SWIPED) Stage II [Phase 2]
A Phase 2 trial called SWIPED Stage II is testing whether propofol-induced slow-wave sleep can treat depression; the study is currently recr…
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CLINICAL_TRIALS research · 2025-10-23Clinical Trial Update: RESISTance Exercise for Depression Trial [NA]
Clinical trial update for the RESISTance Exercise for Depression trial investigating exercise as a treatment for Major Depressive Disorder. …
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CLINICAL_TRIALS research · 2025-10-23Clinical Trial Update: Stress Dynamics and Familial Risk for Depression in Female Adolescents [NA]
This clinical trial update shows the study 'Stress Dynamics and Familial Risk for Depression in Female Adolescents' is currently recruiting …
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CLINICAL_TRIALS research · 2025-10-22Clinical Trial Update: South Asians With Type 2 Diabetes at Risk for Depression [NA]
This clinical trial update notes a study examining depression risk among South Asian individuals with Type 2 diabetes. The trial is currentl…
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CLINICAL_TRIALS research · 2025-10-22Clinical Trial Update: Targeting Network Dysfunction in Apathy of Late-life Depression Using Digital Therapeutics [NA]
A clinical trial is investigating digital therapeutics to target network dysfunction in apathy associated with late-life depression and is c…
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CLINICAL_TRIALS research · 2025-10-22Clinical Trial Update: Assessing an EEG Biomarker of Response to TMS for Major Depression
An ongoing clinical trial is evaluating an EEG biomarker to predict which patients with major depressive disorder respond to transcranial ma…
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CLINICAL_TRIALS research · 2025-10-22Clinical Trial Update: Training Reward Responsiveness Through Virtual Reality [Phase 2]
A Phase 2 clinical trial sponsored by the University of California, Los Angeles is evaluating training reward responsiveness using virtual r…
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CLINICAL_TRIALS research · 2025-10-22Clinical Trial Update: Mindful Moms Randomized Control Trial [NA]
Mindful Moms is an ongoing randomized controlled trial at Virginia Commonwealth University. It tests a mindfulness-based intervention for de…
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CLINICAL_TRIALS research · 2025-10-21Clinical Trial Update: Beyond Monoamines: The Role of the Nociceptin/Orphanin FQ Receptor in Major Depression
This clinical trial update describes research into the nociceptin/orphanin FQ receptor as a potential target for major depressive disorder a…
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CLINICAL_TRIALS research · 2025-10-21Clinical Trial Update: Sexual and Gender Minority Youth (SGMY) and Online Interventions to Increase Help-seeking for Anxiety and/or Depression [NA]
This completed clinical trial evaluated online interventions to increase help-seeking for anxiety and depression among sexual and gender min…
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CLINICAL_TRIALS research · 2025-10-21Clinical Trial Update: Mental Health CPR for Cancer Survivors [NA]
Recruitment is open for a clinical trial evaluating mental health CPR for cancer survivors, focusing on depression and anxiety disorders in …
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CLINICAL_TRIALS research · 2025-10-20Clinical Trial Update: Assessment of Music Experiences in Navigating Depression Part 2 [NA]
This clinical trial update indicates a recruiting study by Icahn School of Medicine at Mount Sinai exploring how music experiences can help …
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CLINICAL_TRIALS research · 2025-10-16Clinical Trial Update: fMRI Accelerated TMS Depression
An ongoing clinical trial at Medical University of South Carolina is evaluating accelerated, fMRI-guided transcranial magnetic stimulation f…
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CLINICAL_TRIALS research · 2025-10-15Clinical Trial Update: Using rTMS to Treat Depression
This entry notes an ongoing clinical trial at Florida International University evaluating repetitive transcranial magnetic stimulation (rTMS…
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CLINICAL_TRIALS research · 2025-10-14Clinical Trial Update: Psilocybin in Chronic Low Back Pain and Depression [Phase 1]
A Phase 1 clinical trial at Johns Hopkins is evaluating the safety and potential effects of psilocybin for chronic low back pain and depress…
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CLINICAL_TRIALS research · 2025-10-14Clinical Trial Update: Effect of Vagal Nerve Stimulation on Gastric Motor Functions [NA]
A Mayo Clinic study is currently recruiting to evaluate the effect of vagus nerve stimulation on gastric motor function in people with depre…
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CLINICAL_TRIALS research · 2025-10-14Clinical Trial Update: Intravenous Ketamine for Treatment-Resistant Depression [Phase 2]
Phase 2 clinical trial evaluating intravenous ketamine for treatment-resistant depression is currently recruiting.
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CLINICAL_TRIALS research · 2025-10-09Clinical Trial Update: Acceptability and Feasibility of Work-Oriented Social-Cognitive Skills Training for Veterans With Serious Mental Illness [NA]
A clinical trial record describing a study on the acceptability and feasibility of a work-oriented social-cognitive skills training for vete…