Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-11-14Clinical Trial Update: Comorbid Obesity and Depression With an Anti-inflammatory Medication [NA]
A clinical trial at King's College London is recruiting to evaluate an anti-inflammatory medication for individuals with obesity and major d…
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CLINICAL_TRIALS research · 2025-11-14Clinical Trial Update: Understanding the Role of Doulas in Supporting People With PMADs [NA]
This clinical trial update shows that the University of Montana is recruiting participants to study how doula support affects outcomes for p…
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CLINICAL_TRIALS research · 2025-11-13Clinical Trial Update: Expansion and Evaluation of AI-generated Clinical Assessment (AI-COA®) of Depression and Anxiety Severity [NA]
This clinical trial update indicates expansion and evaluation of an AI-based Clinical Outcome Assessment (AI-COA) for measuring depression a…
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CLINICAL_TRIALS research · 2025-11-13Clinical Trial Update: Being Safe, Healthy, And Positively Empowered (BSHAPE) Intervention Study [NA]
The BSHAPE Intervention Study is currently recruiting to evaluate an intervention aimed at safety, health, and positive empowerment for indi…
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CLINICAL_TRIALS research · 2025-11-13Clinical Trial Update: Researching Heat and Yoga for Mood Enhancement [NA]
Massachusetts General Hospital is conducting a clinical trial to evaluate whether heat exposure combined with yoga can improve mood in indiv…
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CLINICAL_TRIALS research · 2025-11-13Clinical Trial Update: Comparing the Efficacy of Heated Yoga and Sauna as a Treatment for Depression [NA]
This clinical trial compares heated yoga and sauna as potential treatments for depression and is currently recruiting participants.
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CLINICAL_TRIALS research · 2025-11-13Clinical Trial Update: Cold and Heat Investigation to Lower Levels of Depression [NA]
A clinical trial is investigating whether cold and heat interventions can lower depression symptoms and mood disorders; the study is current…
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CLINICAL_TRIALS research · 2025-11-12Clinical Trial Update: Women's Health Initiative Strong and Healthy Study [NA]
The Women's Health Initiative Strong and Healthy study has completed and reports cardiovascular and other health outcomes. It tracks events …
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CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: Psilocybin Intervention for Veterans Overcoming Treatment-Resistant Depression [Phase 3]
Phase 3 clinical trial evaluating psilocybin for treatment-resistant major depression in veterans is not yet recruiting.
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CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: Behavioral Health Program for Short-Stay Nursing Facility Residents & Care Partners [NA]
Massachusetts General Hospital is conducting a clinical trial to test a behavioral health program for short-stay nursing facility residents …
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CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: Social Needs Screening and Chronic Diseases Study (WE CARE) [NA]
This clinical trial update describes the WE CARE study on social needs screening and chronic diseases, sponsored by the University of Massac…
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CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: Transcranial Direct Current Stimulation for Depression [NA]
Soterix Medical is recruiting for a clinical trial evaluating transcranial direct current stimulation as a treatment for major depressive di…
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CLINICAL_TRIALS research · 2025-11-06Clinical Trial Update: A Tailored and Digital Approach to Address Equity and Support Well-being for Healthcare Workers in the Era of COVID [NA]
This clinical trial update describes a tailored digital program aimed at promoting equity and well-being among healthcare workers during COV…
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CLINICAL_TRIALS research · 2025-11-06Clinical Trial Update: Treating Major Depression With Yoga Mono-therapy [NA]
A University of California, San Francisco trial is evaluating yoga as mono-therapy for mild-to-moderate major depressive disorder and is cur…
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CLINICAL_TRIALS research · 2025-11-06Clinical Trial Update: Developing a Digital Intervention for Adolescent Nonsuicidal Self-injury [NA]
A clinical trial update describes development of a digital intervention for adolescents with nonsuicidal self-injury, depression, and anxiet…
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CLINICAL_TRIALS research · 2025-11-05Clinical Trial Update: Improving Outcomes in Depression in Primary Care in a Low Resource Setting [Phase 3]
A Phase 3 clinical trial in primary care settings in a low-resource environment aims to improve outcomes for patients with major depressive …
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CLINICAL_TRIALS research · 2025-11-05Clinical Trial Update: Mood and Thought Process Study [NA]
A Butler Hospital-sponsored mood and thought process study is recruiting participants for depression-related conditions, including depressio…
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CLINICAL_TRIALS research · 2025-11-05Clinical Trial Update: RXWell to Decrease Post-Operative Opioid Use in Total Knee or Hip Arthroplasty [NA]
A clinical trial update indicates RXWell is recruiting to test whether it can decrease post-operative opioid use in patients undergoing tota…
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CLINICAL_TRIALS research · 2025-11-05Clinical Trial Update: Comparing Behavior Therapy and Yoga for Treating Depression Among Adults [NA]
A clinical trial comparing behavior therapy and yoga as treatments for depression in adults; the study is currently active but not recruitin…
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CLINICAL_TRIALS research · 2025-11-05Clinical Trial Update: TEAMS R34 #3: Team-Based Implementation Strategy for Pediatric Depression Screening [NA]
Update on the TEAMS R34 #3 trial evaluating a team-based implementation strategy for pediatric depression screening; the study is currently …
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CLINICAL_TRIALS research · 2025-11-04Clinical Trial Update: Aspirin in Reducing Events in the Elderly-Extension (ASPREE-XT)
ASPREE-XT is an extension study of the aspirin trial in older adults, with active but not recruiting status to continue evaluating aspirin's…
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CLINICAL_TRIALS research · 2025-11-03Clinical Trial Update: Postpartum Education Via Artificial Intelligence for Recovery and Loneliness: A Randomized Controlled Trial [NA]
A randomized controlled trial assessing an AI chatbot for postpartum education to aid recovery and reduce loneliness, with recruitment not y…
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CLINICAL_TRIALS research · 2025-10-31Clinical Trial Update: Processes and Circuitry Underlying Threat Sensitivity as a Treatment Target for Co-morbid Anxiety and Depression [Phase 4]
Phase 4 clinical trial investigating the neural processes and circuitry underlying threat sensitivity as a treatment target for co-morbid an…
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CLINICAL_TRIALS research · 2025-10-31Clinical Trial Update: Pharmacologic Augmentation of TMS for Depression With D-serine [Phase 1]
A Phase 1 trial is assessing whether D-serine can augment transcranial magnetic stimulation for depression and it is currently recruiting.
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CLINICAL_TRIALS research · 2025-10-30Clinical Trial Update: A Mechanistic Study to Assess a Single Dose of CYB003 in Participants With Depression and Anxiety [Phase 2]
A Phase 2 mechanistic study to assess a single dose of CYB003 in participants with depression and anxiety, currently not recruiting.