Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-11-26Clinical Trial Update: Psilocybin rTMS for Treatment Resistant Depression [Phase 2]
A Phase 2 clinical trial at the University of Texas at Austin is testing psilocybin-assisted rTMS for treatment-resistant depression and is …
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CLINICAL_TRIALS research · 2025-11-25Clinical Trial Update: Multimodal Phenotyping in Adolescent Inpatient Depression: An Observational Study
This observational study aims to explore multimodal phenotyping in adolescents hospitalized with depression and is currently recruiting.
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CLINICAL_TRIALS research · 2025-11-25Clinical Trial Update: Dapagliflozin in Depression [Phase 1, Phase 2]
A clinical trial is evaluating dapagliflozin for depression in Phase 1 and Phase 2; recruitment is ongoing at Tanta University.
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CLINICAL_TRIALS research · 2025-11-25Clinical Trial Update: Two Doses of Psilocybin for the Treatment of MDD in Adults With Cancer [Phase 2]
Phase 2 clinical trial evaluating two doses of psilocybin for major depressive disorder in adults with cancer is currently recruiting.
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CLINICAL_TRIALS research · 2025-11-25Clinical Trial Update: Predictors and Process Moderators of EMDR Therapy for Depressive Symptoms
A clinical trial from the University of Turin is investigating predictors and process moderators of EMDR therapy for depressive symptoms, wi…
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CLINICAL_TRIALS research · 2025-11-25Clinical Trial Update: Characterizing Cognitive Decline in Late Life Depression: The ADNI Depression Project
This update describes the ADNI Depression Project led by the University of Southern California to study cognitive decline in individuals wit…
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CLINICAL_TRIALS research · 2025-11-25Clinical Trial Update: Ketamine-Enhanced Therapy for Individuals With Alcohol Use Disorder and Depression: A Pilot Study (KET-DUAL) [Phase 1, Phase 2]
A Phase 1/2 pilot trial evaluating ketamine-enhanced therapy for individuals with alcohol use disorder and major depressive disorder; the st…
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CLINICAL_TRIALS research · 2025-11-25Clinical Trial Update: Equipping Patients Using Interventions for Pain and Depression [NA]
Indiana University is recruiting participants for a clinical trial aimed at interventions for chronic pain and depression, including musculo…
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CLINICAL_TRIALS research · 2025-11-24Clinical Trial Update: An Individual-specific Synchrony Signature [NA]
An ongoing clinical trial is investigating an individual-specific synchrony signature for Major Depressive Disorder and is currently recruit…
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CLINICAL_TRIALS research · 2025-11-24Clinical Trial Update: The Pregnancy and Postpartum Mental Health Optimization Virtual Intervention Network [NA]
A clinical trial from Women's College Hospital evaluating a virtual intervention network to optimize mental health during pregnancy and post…
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CLINICAL_TRIALS research · 2025-11-24Clinical Trial Update: Evaluating the Effectiveness of an Online Cognitive Behavioral Therapy Program for University Students With Depression and/or Anxiety [NA]
This clinical trial update reports on the ongoing evaluation of an online cognitive behavioral therapy program for university students with …
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CLINICAL_TRIALS research · 2025-11-24Clinical Trial Update: Families With Pride ("Familias Con Orgullo"). [NA]
A clinical trial update from the University of Miami for a study titled Families With Pride (Familias Con Orgullo) investigating depression …
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CLINICAL_TRIALS research · 2025-11-21Clinical Trial Update: Accelerated TMS for MDD [NA]
A clinical trial update shows accelerated transcranial magnetic stimulation is being studied for major depressive disorder. The study (NCT07…
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CLINICAL_TRIALS research · 2025-11-21Clinical Trial Update: Empower@Home: Hybrid Effectiveness-Implementation Randomized Controlled Trial (RCT) [NA]
The Empower@Home trial is a hybrid effectiveness-implementation randomized controlled trial for depression, and it is currently recruiting.
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CLINICAL_TRIALS research · 2025-11-21Clinical Trial Update: Empower@Home: Community Implementation for Older Adults With Ambulatory Disabilities [NA]
Clinical trial update for Empower@Home, a community implementation study for older adults with ambulatory disabilities addressing depression…
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CLINICAL_TRIALS research · 2025-11-21Clinical Trial Update: Internet-Delivered Psychological Treatment for Cancer Survivors [NA]
A Karolinska Institutet-led clinical trial evaluating internet-delivered psychological treatment for cancer survivors with anxiety and depre…
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CLINICAL_TRIALS research · 2025-11-20Clinical Trial Update: Structured Group Therapy in Reducing Depression and Anxiety in Pakistan [NA]
A clinical trial update from the Pakistan Association of Cognitive Therapists on structured group therapy aimed at reducing depression and a…
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CLINICAL_TRIALS research · 2025-11-20Clinical Trial Update: A Study on the Effectiveness of Comprehensive Intervention Based on Specialized Physical Education Courses in the Prevention of Comorbidity Among Junior Middle School Students [NA]
A clinical trial update describes a study of a comprehensive physical education-based intervention to prevent comorbidity in junior middle s…
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CLINICAL_TRIALS research · 2025-11-19Clinical Trial Update: Health and Wellness After Preterm Birth [NA]
A completed clinical trial from Children's Hospital of Philadelphia studying health and wellness after preterm birth, including outcomes rel…
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CLINICAL_TRIALS research · 2025-11-19Clinical Trial Update: Pilot Testing Into the Feasibility of the Developed Cognitive Behavioral Therapy Intervention [NA]
This clinical trial update describes the feasibility pilot of a developed cognitive behavioral therapy intervention for participants with HI…
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CLINICAL_TRIALS research · 2025-11-19Clinical Trial Update: A Randomized Controlled Trial of Robotic Support for Enhanced Later Life (RoSELL) [NA]
An update on the RoSELL randomized trial evaluating robotic support to address loneliness and depressive symptoms in older adults, with the …
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: Integrating Inuit Knowledge Principles in Multi-Level Mental Health Clinical Trials [EARLY_Phase 1]
This early-phase trial focuses on integrating Inuit knowledge principles into multi-level mental health clinical trials for depression and a…
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: Building Connections [NA]
Massachusetts General Hospital is recruiting for a clinical trial covering colorectal cancer, cervical cancer, depression, anxiety, and obes…
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: Internet-Delivered Cognitive Behaviour Therapy for Depression and Anxiety in Perinatal Parents [NA]
This clinical trial is evaluating internet-delivered cognitive behavioral therapy for anxiety and depression in perinatal parents and is cur…
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: Mechanisms Of Orbitofrontal Stimulation in Depression [NA]
This clinical trial is exploring the mechanisms of orbitofrontal cortex stimulation as a treatment for Major depressive disorder and is curr…