Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-12-23Clinical Trial Update: Electroacupuncture on Treating Cancer-related Depression [NA]
A clinical trial is ongoing to evaluate electroacupuncture for cancer-related depression; recruitment is currently open.
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CLINICAL_TRIALS research · 2025-12-22Clinical Trial Update: Nitrous Oxide- Suicidal Ideation [Phase 1]
A Phase 1 clinical trial at Washington University School of Medicine investigates nitrous oxide for suicidal ideation in individuals with ma…
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CLINICAL_TRIALS research · 2025-12-22Clinical Trial Update: Lifestyle Intervention for Symptoms of Depression wIth App Support in General Practice [NA]
A clinical trial evaluating a lifestyle intervention for depressive and anxiety symptoms with app support in general practice is currently r…
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CLINICAL_TRIALS research · 2025-12-22Clinical Trial Update: Depression, Aging, Stress and Heart Health Study [NA]
University of North Carolina, Chapel Hill is conducting a recruiting clinical study to investigate depression, aging, stress, menopause, and…
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CLINICAL_TRIALS research · 2025-12-22Clinical Trial Update: Ultra-brief Psychological Treatments for Emotional Symptoms and Disorders [NA]
Clinical trial NCT06909669 from Universidad de Córdoba studies ultra-brief psychological treatments for emotional symptoms and disorders. Th…
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CLINICAL_TRIALS research · 2025-12-22Clinical Trial Update: Escitalopram Plasma Concentrations in Premenopausal and Postmenopausal Women
A ClinicalTrials.gov update describes a study evaluating escitalopram plasma concentrations in premenopausal versus postmenopausal women, wi…
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CLINICAL_TRIALS research · 2025-12-19Clinical Trial Update: Investigation of the Effect of Massage Application on Functional Status and Depression in Postpartum Mothers
Completed clinical trial investigating whether massage affects functional status and depressive symptoms in postpartum mothers.
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CLINICAL_TRIALS research · 2025-12-19Clinical Trial Update: Prediction of REsponse to Depression Interventions (Accelerated rTMS) Using Clinical and TD-fNIRS Measurements
A Kernel-sponsored clinical trial is recruiting to predict response to depression interventions using accelerated rTMS. It combines clinical…
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: Parcel-guided rTMS for Major Depressive Disorder [Phase 2]
Phase 2 clinical trial update on parcel-guided rTMS by Soterix Medical for major depressive disorder with treatment-resistant depression; th…
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: Psychological State, Immunotherapy Response, and Multi-Omics Signatures in TNBC
An ongoing clinical trial at Fudan University investigates how psychological state influences immunotherapy response in triple-negative brea…
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: Ketamine-assisted Integrative Treatment for Veterans With Chronic Low Back Pain and Comorbid Depression [Phase 2]
Phase 2 clinical trial investigating ketamine-assisted integrative treatment for veterans with chronic low back pain and comorbid depression…
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: Evaluating Process of Change in Cognitive Behavioral Therapy and Acceptance and Commitment Therapy for Depression [NA]
A clinical trial update from the University of Southern California evaluating processes of change in Cognitive Behavioral Therapy and Accept…
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: Pharmaco-Neuroimaging Studies of Approach/Avoidance Behaviors and Post-Mortem Studies: Pharmacological Manipulation [Phase 2]
Phase 2 pharmacological neuroimaging trial investigating approach/avoidance behaviors in Major depressive disorder and anxiety disorders; re…
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: Teachers Leading the Front Lines - Adolescent [NA]
A University of North Carolina study is recruiting adolescents to address behavioral and emotional problems, including depression and anxiet…
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: CBT-I vs. MBTI for Traumatic Brain Injury (TBI)-Related Insomnia and Post-Traumatic Stress Symptoms [NA]
Johns Hopkins University is conducting a study comparing Cognitive Behavioral Therapy for Insomnia (CBT-I) and MBTI for insomnia and PTSD-re…
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: Impact of Nut Consumption on Mental Health in Young Adults [NA]
A clinical trial update announcing ongoing recruitment to study the effects of nut consumption on mental health in young adults, focusing on…
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: The Effects of Chiropractic on Adults With Depression [NA]
Clinical trial evaluating the effects of chiropractic on adults with depression; currently not recruiting.
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: Neuroscience of Psychotherapy for Depression [NA]
This entry notes an ongoing clinical trial investigating the neuroscience behind psychotherapy for depression, currently recruiting particip…
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: Promoting Positive Emotions in Adolescents Using Positive Events Training: An Indicated Approach [NA]
A KU Leuven clinical trial is evaluating Positive Events Training to promote positive emotions in adolescents with emotional distress and an…
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: Validating an Autonomous Interactive Internet-Based Delivery of an Empirically Supported Cognitive Behavioral Therapy for Comorbidity [NA]
This clinical trial update notes ongoing recruitment for a study validating an autonomous internet-based delivery of empirically supported c…
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: A Trial of a Positive Psychology Intervention for Older Adults (RESET) [NA]
A University of Michigan–led trial (RESET) is evaluating a positive psychology intervention for older adults with depressive symptoms and an…
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: Bilateral Prefrontal and Insular TMS for Depression in Schizophrenia [NA]
This clinical trial update describes a study evaluating bilateral prefrontal and insular transcranial magnetic stimulation for depression in…
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: Feasibility Trial of Exercise as a Priming Strategy for rTMS Treatment in Difficult-to-Treat Depression [NA]
ClinicalTrials.gov update describing a feasibility study evaluating whether exercise can prime response to repetitive transcranial magnetic …
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: Meditation Accelerated Brain Stimulation for Depression [NA]
A clinical trial update describes a study on meditation-accelerated brain stimulation for depression; the study is currently active but not …
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: Attenuating DEPression With Internet CBT to Slow Cognitive Decline in Older ICU Survivors(ADEPT-ICU) [NA]
A clinical trial (ADEPT-ICU) is evaluating internet-delivered cognitive behavioral therapy to treat depression and slow cognitive decline in…