Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: Behavioral Activation for Depression and Habitual Rumination [NA]
A clinical trial update indicates a study evaluating Behavioral Activation for Depression and Habitual Rumination in individuals with major …
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: Training in Evidence-based Treatments in Psycho-Oncology [NA]
This ClinicalTrials.gov entry describes a Massachusetts General Hospital study focused on training in evidence-based treatments for psycho-o…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: Antidepressant Effects of Nitrous Oxide [Phase 2]
Phase 2 clinical trial evaluating the antidepressant effects of nitrous oxide in major depressive disorder and treatment-resistant depressio…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: Investigating the Brain's Physiological Responses in Depression and Autism, Using Transcranial Magnetic Stimulation and Electroencephalography
A clinical trial from National Taiwan University Hospital is enrolling individuals with autism and major depressive disorder to study brain …
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: Adapted Visual Safety Plan for Autistic Youth (VSP-AY) to Address Self-harm, Suicidal Ideation, and Suicide Behaviors [NA]
Clinical trial update describes the Adapted Visual Safety Plan for Autistic Youth (VSP-AY) aimed at addressing self-harm, suicidal ideation,…
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CLINICAL_TRIALS research · 2026-01-09Clinical Trial Update: Physical Therapy for Depression Quality of Life (Pilot Study Protocol) [NA]
A pilot study protocol evaluating physical therapy to improve quality of life for adults with major depressive disorder; sponsor is Universi…
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CLINICAL_TRIALS research · 2026-01-09Clinical Trial Update: Spaced Transcranial Direct Current Stimulation for Treatment-Resistant Depression: A Home-Based Feasibility and Safety Study [NA]
This clinical trial update reports a home-based feasibility and safety study of spaced transcranial direct current stimulation for treatment…
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CLINICAL_TRIALS research · 2026-01-09Clinical Trial Update: Behavioral Activation Delivered Via Home-based Telehealth to Improve Functioning in Cardiovascular Disease Patients Recently Discharged From Inpatient Care [Phase 3]
Phase 3 clinical trial evaluating home-based telehealth-delivered Behavioral Activation therapy. It aims to improve functioning in patients …
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CLINICAL_TRIALS research · 2026-01-09Clinical Trial Update: Personalized Ultrasonic Brain Stimulation for Depression (R61) [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating personalized ultrasonic brain stimulation for major depressive disorder, currently recruiting.
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CLINICAL_TRIALS research · 2026-01-09Clinical Trial Update: Integrating Treatment for Mental Disorders in Methadone Clinics in Ukraine [NA]
The study aims to integrate treatment for mental disorders, including depression and opioid use disorder, within methadone clinics in Ukrain…
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CLINICAL_TRIALS research · 2026-01-09Clinical Trial Update: Neurobiological and Genomic Predictors of Relapse in Depression
A recruiting clinical study examining neurobiological and genomic predictors of relapse in major depressive disorder, with healthy volunteer…
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CLINICAL_TRIALS research · 2026-01-09Clinical Trial Update: A Clinical Study Evaluating the Efficacy and Safety of CreNeuriS CNS Herbal Nutrition Capsules for Participants With Mild Depressive Disorder Comorbid With Anxiety Disorder [NA]
A clinical study evaluating the efficacy and safety of CreNeuriS CNS Herbal Nutrition Capsules for individuals with mild depressive disorder…
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CLINICAL_TRIALS research · 2026-01-09Clinical Trial Update: An Examination of the Performance of QbMobile in Differential Diagnosis Associated With ADHD Symptoms
This clinical trial update reviews the performance of QbMobile in aiding differential diagnosis for ADHD symptoms across multiple psychiatri…
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CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: The PATHway Study: Primary Care Based Depression Prevention in Adolescents [NA]
The PATHway Study is a primary care-based program aimed at preventing depression in adolescents; the trial is currently active but not recru…
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CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: Text -Based Depression Screening Among Cancer Survivors [NA]
A recruiting clinical trial evaluating a text-based approach to screen for depression among cancer survivors to identify depressive symptoms…
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CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: Individualized Targeting and Neuromodulation of Late-Life Depression [NA]
Clinical trial update on individualized targeting and neuromodulation for late-life depression (major depressive disorder), sponsored by the…
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CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: Machine Learning-based Classification of Symptom Clusters and Online CBT [NA]
A Wuhan Mental Health Centre study tests machine learning classification of depression and anxiety symptom clusters and online cognitive-beh…
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Well-being Training for Adolescent Depressive Symptoms (TeenWell Study) [NA]
This entry describes a clinical trial investigating well-being training to address depressive symptoms in adolescents. Recruitment is ongoin…
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Subanesthetic Esketamine in Modified ECT for Severe Depression in Adolescents: Clinical and Mechanistic Study [EARLY_Phase 1]
An early-phase study is evaluating subanesthetic esketamine as an adjunct to modified electroconvulsive therapy for severe depression in ado…
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Accelerated High-Dose tDCS for Depression [NA]
A clinical trial is evaluating accelerated high-dose transcranial direct current stimulation for major depressive disorder. The study is cur…
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Rapid Antidepressant Dynamics in Acute Neuromodulation Treatments [NA]
This clinical trial update notes a not-yet-recruiting study exploring rapid antidepressant dynamics with acute neuromodulation, sponsored by…
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Electroconvulsive Therapy Augmented With Transcranial Magnetic Stimulation for Treatment Resistant Depression [NA]
A clinical trial evaluating whether adding transcranial magnetic stimulation to electroconvulsive therapy for treatment-resistant depression…
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Optimizing the AYA Survivors' Coping and Emotional Needs Toolkit [NA]
East Carolina University is recruiting for a trial testing a coping and emotional needs toolkit to support adolescent and young adult cancer…
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Interactive Technological Intervention to Improve Mental Health Symptoms in Primary Health Care [NA]
This is a clinical trial update describing an interactive technological intervention designed to improve depression, anxiety, and insomnia s…
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CLINICAL_TRIALS research · 2026-01-06Clinical Trial Update: Cerebral and Anti-inflammatory Response Through Exercise - Mechanisms In Depressive Disorders [NA]
An ongoing study investigating how exercise influences cerebral and systemic inflammatory responses to elucidate mechanisms in Major depress…