Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: Intensified Pharmacological Treatment for Schizophrenia, Major Depressive Disorder and Bipolar Depression After a First-time Treatment Failure [Phase 3]
This Phase 3 clinical trial is recruiting to test intensified pharmacological treatment for schizophrenia, major depressive disorder, and bi…
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: Effectiveness of the Safe Haven Application (App) Among Undergraduates [NA]
Clinical trial status update indicates the Safe Haven Application is currently recruiting undergraduates to evaluate its effectiveness for d…
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: Managing Hepatitis B (Hep. B) and Human Papilloma Virus (HPV) Related Cancers and Mental Health. [Phase 4]
Phase 4 clinical trial update on managing hepatitis B and HPV-related cancers and associated mental health conditions. The study is currentl…
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: AtWork: The Relation Between Cognitive Functioning, Common Mental Disorders and Work Functioning
This recruiting clinical trial from the Norwegian University of Science and Technology investigates how cognitive functioning relates to wor…
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: Validation of the French Version of the Edinburgh Postnatal Depression Scale (EPDS) Postnatally in the Father [NA]
This clinical trial validates a French version of the Edinburgh Postnatal Depression Scale for use in fathers after birth and is currently r…
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: Effectiveness, Implementation, and Cost of Cognitive Processing Therapy in Prisons [NA]
A clinical trial evaluating the effectiveness, implementation, and cost of Cognitive Processing Therapy for prisoners with PTSD, including c…
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: Psilocybin for Treatment-Resistant Depression [Phase 2]
Phase 2 clinical trial update on psilocybin for treatment-resistant major depressive disorder; the study is currently active but not recruit…
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: Study of ABX-002 for the Adjunctive Treatment of Depressive Episodes Associated With Bipolar Disorder in Adults [Phase 2]
A Phase 2 clinical trial update for ABX-002 as an adjunctive treatment for depressive episodes in adults with bipolar disorder, currently re…
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: DBS for Depression [Phase 1]
A Phase 1 clinical trial sponsored by Northwell Health evaluating deep brain stimulation for treatment-resistant depression is currently rec…
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: PCS in Severe Treatment Resistant Depression [NA]
A clinical trial evaluating PCS for severe treatment-resistant depression is currently recruiting at the University of Minnesota.
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: Study of ABX-002 for the Adjunctive Treatment of Major Depressive Disorder (AMPLIFY) [Phase 2]
ABX-002 is being studied as an adjunctive treatment for adults with major depressive disorder in the AMPLIFY trial. The Phase 2 study is cur…
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CLINICAL_TRIALS research · 2026-01-16Clinical Trial Update: Salivary Oxytocin as a Biomarker of Psychedelic Treatment
A University of Geneva-led trial is investigating whether salivary oxytocin can serve as a biomarker for psychedelic-assisted treatment in m…
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: HIV-Mental Illness Stigma Reduction and Outcomes in Malawi [NA]
A Malawi-based study sponsored by the University of Pennsylvania is evaluating HIV and mental illness stigma and related outcomes, with enro…
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: Study on Treatment Mechanisms and Efficacy Prediction of Individualized Transcranial Magnetic Stimulation in Adults With Irritable Bowel Syndrome Using Multimodal MRI and High-Throughput Sequencing [NA]
This clinical trial update describes an enrolling-by-invitation study evaluating individualized transcranial magnetic stimulation for irrita…
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: Integrated Suicide & Trauma Therapy for Suicide Risk [NA]
A clinical trial recruiting to test an integrated suicide and trauma therapy designed to reduce suicide risk in individuals with trauma expo…
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: The WeACT Program for Family Caregivers of People Living With Dementia [NA]
The WeACT Program is a clinical trial to support family caregivers of people living with dementia, with recruitment not yet started.
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: Latino Teen Depression Treatment Study
A Duke University-led clinical trial studying treatments for depression in Latino teenagers is currently recruiting participants.
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: Meditative Neurofeedback for Depression [NA]
This ClinicalTrials.gov entry documents a recruiting study evaluating meditative neurofeedback as a potential treatment for major depressive…
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: The Effect of Digital Markers in the Self-management of Depressive Symptoms [NA]
This clinical trial update reports on an enrolling-by-invitation study investigating how digital markers can aid self-management of depressi…
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: Adolescent Mood During Puberty and Testosterone [NA]
A clinical trial is recruiting to study how puberty and testosterone influence mood in adolescents with depression. The study is sponsored b…
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: Dosing rTMS for Depression Post-SCI [NA]
This clinical trial update reports ongoing recruitment for dosing parameters of repetitive transcranial magnetic stimulation (rTMS) to treat…
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CLINICAL_TRIALS research · 2026-01-13Clinical Trial Update: Effects of a Classic High-frequency rTMS Treatment Versus a Deep rTMS Treatment [NA]
A clinical trial compares classic high-frequency rTMS with deep rTMS for treatment-resistant depression and is currently recruiting.
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CLINICAL_TRIALS research · 2026-01-13Clinical Trial Update: University of North Carolina Alumni Heart Study
Clinical trial update on the University of North Carolina Alumni Heart Study, sponsored by Duke University, shows the study is active but no…
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CLINICAL_TRIALS research · 2026-01-13Clinical Trial Update: Clinical Trial to Investigate the Safety and Efficacy of Two Dexamfetamine Sulfate Formulations in Adults With ADHD and Moderate to Severe Depression [Phase 2]
Phase 2 clinical trial update evaluating two dexamfetamine sulfate formulations for safety and efficacy in adults with ADHD and major depres…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: First-In-Human (FIH), Single Ascending Dose (SAD) Study and Multiple Ascending Dose (MAD) Study of SP-101 Injection [Phase 1]
This is a first-in-human Phase 1 study evaluating single ascending dose and multiple ascending dose cohorts of SP-101 injection in adults wi…